Results 91 to 100 of about 4,154 (224)

Schiff Base–Derived Colorimetric Chemosensor for Fe3+ Detection: Synthesis, Mechanistic Insights, and Real‐World Applications in Water Quality Monitoring

International Journal of Analytical Chemistry, Volume 2026, Issue 1, 2026.
A Schiff base colorimetric chemosensor (H2L), synthesized from 2‐hydroxy‐1‐naphthaldehyde and anthranilic acid, was developed for selective Fe3+ detection. In a DMF:H2O (9:1, v/v) medium, H2L exhibited a distinct and selective response to Fe3+ among common competing cations, producing a visible color change from yellow to black and a new broad ...
Shahad Ayed Alahmady, Syed Nazreen, Ali Q. Alorabi, Bewketu Mehari   +3 more
wiley   +1 more source

Rational Design of Pyrazole–Chalcone Congeners via Enumeration: Insights From Molecular Docking, MM‐GBSA, Pharmacophore Modelling, MD Simulations and DFT Calculations

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Background Monoamine oxidase‐B (MAO‐B) is a pivotal enzyme in the pathophysiology of Parkinson’s disease (PD), where its elevated activity accelerates dopamine catabolism, increases oxidative stress and contributes to the progressive loss of dopaminergic neurons.
Zakiya Fathima C., Jainey P. James, Srinivas Ganjipete, Parasuraman Pavadai, Sindhu T. J., Sohini Basu Roy   +5 more
wiley   +1 more source

Cytotoxic potential of novel N-formyl pyrazolines derived from vanillin [PDF]

Kragujevac Journal of Science
In the reaction of vanillin and acetone under Claisen-Schmidt conditions, dehydrozingerone, a very attractive biologically active compound, is obtained.
Muškinja Jovana M., Marković Violeta R., Todorović Tamara Lj, Luković Jovan D., Nikolić Ivana S., Mitrović Marina M., Ratković Zoran R.   +6 more
doaj   +1 more source

Metal-catalyzed cyclopropanation on the 8-oxabicyclo[3.2.1]oct-6-ene template [PDF]

, 2005
Cyclopropanations of an 8-oxabicyclo[3.2.1]octene substrate using diazocarbonyl compounds provided exo, exo-cyclopropanated products as the sole or major diastereomeric oxatricyclic products.
Chiu, P, Leung, SK
core   +1 more source

Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives

Journal of Chemistry, Volume 2026, Issue 1, 2026.
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal, Elvira Hermawati, Ace Tatang Hidayat, Dadan Sumiarsa, Ika Wiani Hidayat, Jamaludin Al-Anshori, Tulika Banerjee   +6 more
wiley   +1 more source

SYNTHESIS AND CHARACTERIZATION OF [(5-MERCAPTO-1,3,4-OXADIAZOL-2-YL)ARYL]-3,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011
The synthesis and characterization of [(5-mercapto-1,3,4-oxadiazol-2-yl)aryl]-3,5-diaryl-4,5-dihydro-1Hpyrazole-1-carbothioamides - derivatives of pyrazolines and 5-[4(3)-isothiocyanatophenyl]-2-thio-1,3,4-oxadiazoles were realized.
Zinaida Ribkovskaia, Serghei Pogrebnoi, Alic Barba, Fliur Macaev   +3 more
doaj  

Asymmetric organocascades involving the formation of two C-heteroatom bonds from two distinct heteroatoms [PDF]

, 2012
International audienceIn the vast and expanding world of enantioselective organocascades, the ones in which two C-heteroatom bonds are created from two distinct heteroatoms are rare.
Bonne, Damien, Constantieux, Thierry, Coquerel, Yoann, Rodriguez, Jean   +3 more
core   +3 more sources

Synthetic Strategies to Access Fluorinated Azoles

European Journal of Organic Chemistry, Volume 28, Issue 47, December 15, 2025.
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
Mohammed K. Abd El‐Gaber, Mario Djugovski, Tzu‐Yu Huang, Sweta Adhikari, Sudeshna Roy   +4 more
wiley   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source