Results 71 to 80 of about 4,154 (224)

SASH: Student Academic Showcase and Honors 2018 [PDF]

, 2017
A celebration of scholarship and creative activities for undergraduate and graduate students held in April, 2018 at the Roger Williams University campus in Bristol, Rhode ...
Roger Williams University
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N1-benzenesulfonyl-2-pyrazoline hybrids in neurological disorders [PDF]

A novel series of 1,3,5-trisubstituted-2-pyrazolines (5a-5t) was prepared via Claisen Schmidt condensation, followed by heterocyclization with hydrazine hydrate, substitution of N1 hydrogen of 2-pyrazoline nucleus with 4-chlorobenzenesulfonylchloride ...
Paliwal, Sarvesh, Saraf, Shailendra K., Tripathi, Avinash C., Upadhyay, Savita   +3 more
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Pyrazoline Derivatives: Synthesis, In Silico, Enzyme Kinetics Studies and Biological Activity against Cholinesterase, Lipoxygenase, and α‐Amylase

ChemistrySelect, Volume 11, Issue 9, 5 March 2026.
ABSTRACT Nucleophilic cyclization of the α, β‐unsaturated carbonyl framework of the prepared (E)‐4‐(3‐bromo‐4‐hydroxy‐5‐methoxyphenyl)but‐3‐en‐2‐one with various hydrazine derivatives to afford their corresponding pyrazolines has been achieved. The enzyme assays conducted showed significant α‐amylase inhibitory activity for 4b with IC50 value of 2.7 µM.
Redolf S. Segodi, E. N. Agbo, Leoma B. Mofeli, K. W. Poopedi, O. O. Oderinlo, W. Nxumalo   +5 more
wiley   +1 more source

2-пиразолины с 8-гидроксихинолиновым заместителем [PDF]

, 2008
Осуществлен синтез 2-пиразолинов на основе халконов 8-гидроксихинолинового ряда и фенилгидразина, строение пиразолинов подтверждено данными элементного анализа, ИК. .1Н ЯМР и электронной спектроскопии.
Марруго Гонсалес, А.Х., Мацаков, А.Ю., Орлов, В.Д.   +2 more
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Easier, Safer, and Greener: Unlocking the Power of Solid Reagents in Organic Reactions by Mechanochemistry

ChemistryEurope, Volume 4, Issue 2, February 2026.
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego, Nicolas Pétry, Julien Pinaud, Olivia Giani, Frédéric Lamaty   +4 more
wiley   +1 more source

Multifaceted Anticancer Activity of Flavanone/Chromanone Intermediates for Five-Membered Heterocyclic Derivatives: Targeting Oxidative Stress, Apoptosis, and MAPK Signaling in Colorectal Cancer

Molecules
This study explores the multifaceted anticancer mechanisms of flavanone analogues and spiropyrazoline condensed with flavanone ring against colorectal cancer (CRC) cell lines.
Pawel Hikisz, Angelika A. Adamus-Grabicka, Elzbieta Budzisz   +2 more
doaj   +1 more source

Reactivity of 4-tert-Butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with Hydrazines

Molecules, 2006
The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described.
Manuel Medarde, Fernando Tomé, Pilar Puebla, Esther Caballero, Javier Figueroa   +4 more
doaj   +1 more source

An overview of 2-Styrylchromones: natural occurrence, synthesis, reactivity and biological properties [PDF]

, 2017
2-Styrylchromones are a small class of oxygen-containing heterocycles. Despite their sparse occurrence in nature, several synthetic approaches have been developed in order to synthesize a large variety of derivatives, possessing different substituents ...
Alonso, Ayyangar, Aziz, Baker, Baptista, Barros, Barros, Bennett, Berar, Bhattacharyya, Cavaleiro, Chaniad, Cheema, Clarke, Conti, Dean, Desideri, Desideri, Dhoubhadel, Doria, Elkashef, Fernandes, Fernandes, Ferreira, Filipe, Fuchigami, Fuchigami, Gaggad, Gaspar, Gerwick, Gerwick, Goel, Gomes, Gomes, Gomes, Gomes, Gomes, Gulati, Gupta, Gupta, Helibron, Hercouet, Jain, Jung, Karton, Kelkar, Keri, Kumar, Kumar, Königs, Lee, Letcher, Letcher, Letcher, Lin, Mahal, Makrandi, Makrandi, Marinho, Marini-Bettòlo, Marona, McGarry, Momin, Momin, Momoi, Mustafa, Nam, Nikam, Obrecht, Ono, Paparao, Patoilo, Patoilo, Pawar, Peixoto, Pereira, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Price, Reddy, Reddy, Robinson, Santos, Santos, Santos, Santos, Santos, Saraf, Schonberg, Sharma, Sharma, Shaw, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Singhi, Sousa, Sousa, Takamatsu, Talhi, Tawfik, Yang, Yang, Yokoe, Yoon, Zammattio, Zammattio, Zammattio   +122 more
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Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel, Cardona G, Wilson I, Coa, Juan Carlos, Conesa Milián, Laura, Robledo, Sara M., Upegui Zapata, Yulieth Alexandra, Yepes, Andrés   +6 more
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Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents

Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar, Magdi E. A. Zaki, Zeinab A. Muhammad, Dahlia A. Awwad, Sami A. Al‐Hussain, Chérif F. Matta, Refaie M. Kassab   +6 more
wiley   +1 more source