Results 71 to 80 of about 950 (182)

Development of novel antimicrobial agents: investigating the efficacy of 1,3,5-Triphenyl-2-pyrazoline derivatives [PDF]

Health Science Monitor
Background & Aims: In this research, a novel series of heterocyclic compounds containing pyrazoline nuclei was synthesized in two steps. Materials & Methods: In the first step, chalcones were prepared using the Claisen-Schmidt reaction between ...
Sevda Afzal-Ahangaran, Yaeghob Sharifi, Maryam Allahyari-Devin   +2 more
doaj  

Design, synthesis and biological evaluation of pyrazoline derivatives for antidepressant activity

Current Issues in Pharmacy and Medical Sciences
Pyrazolines constitute a class of privileged scaffolds in modern medicinal chemistry, particularly as central nervous system-active agents, and several pyrazoline-based drugs are used to treat various neurological disorders.
Dinesh Rishipathak, Komal Ushir, Pavan Udavant, Rahul Sable, Tushar Lokhande   +4 more
doaj   +1 more source

Assessing the effect of N-oxidation on the mutagenicity of 1-pyrazolines using the Ames assay. [PDF]

Toxicol Res (Camb), 2023
Inami K, Miura M, Yoshida M, Mochizuki M.   +3 more
europepmc   +1 more source

Syntheses of New Pyrazoline Derivatives

Chemical and Pharmaceutical Bulletin, 1968
HAYASHI, SEIGORO, FURUKAWA, MITSURU, YAMAMOTO, JUNKO, NISHIZIMA, YOKO, INOUE, KENGO   +4 more
openaire   +3 more sources

Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing. [PDF]

RSC Med Chem
Ciupa A.
europepmc   +1 more source

(3+2)-Cycloadditions of Levoglucosenone (LGO) with Fluorinated Nitrile Imines Derived from Trifluoroacetonitrile: An Experimental and Computational Study. [PDF]

Molecules, 2023
Mlostoń G, Urbaniak K, Palusiak M, Witczak ZJ, Würthwein EU.   +4 more
europepmc   +1 more source

Electricity-Controlled Divergent Synthesis of CF₃‑Tethered Pyrazolines and Pyrazoles via Tandem Radical Trifluoromethylation and Annulation. [PDF]

JACS Au
Pattanayak P, Girase YK, Chatterjee T.
europepmc   +1 more source

Visible-light-induced [3+2] cycloadditions of donor/donor diazo intermediates with alkenes to achieve (spiro)-pyrazolines and pyrazoles. [PDF]

Chem Sci, 2023
Zhang Y, Li Y, Ni SF, Li JP, Xia D, Han X, Lin J, Wang J, Das S, Zhang WD.   +9 more
europepmc   +1 more source

Synthesis of Some Novel Chalcone and 3,5-Disubstituted Pyrazoline Derivatives: Evaluation of Their α-Amylase and α-Glucosidase Inhibitory Activities In Vitro and In Silico. [PDF]

Arch Pharm (Weinheim)
Erbay F, Akatin MY, Demir F, Kahriman N, Colak A, Ertunga NS, Küçük M.   +6 more
europepmc   +1 more source

Novel <i>N</i>-chloroacetyl-2-pyrazoline analogs with 2-naphthyl and ferrocenyl groups: targeting histamine receptor H1 to overcome colorectal cancer drug resistance. [PDF]

Cancer Drug Resist
Veeragoni D, Ghosh H, Ansari A, Bhattacharyya S, Azaz A, Ommi O, Covarrubias-Zambrano O, Köhler LHF, Ködel JF, Hamza A, Kasi A, Bossmann SH, Schobert R, Biersack B, Dandawate P.   +14 more
europepmc   +1 more source