Results 51 to 60 of about 4,154 (224)

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Региоселективный синтез и свойства ацетильных производных фенолгликозидов [PDF]

, 2008
Региоселективный синтез и свойства ацетильных производных фенолгликозидов. Работа посвящена выявлению реакционной способности при кислотном дезацетилировании с использованием HCl / EtOH в CHCl3, которая приводит к дезацетилированию на O-3, O-4 и O-6 ...
Auguste, Bamber, Beadling, Behrmann, Bonifati, Brown, Cross, Damen, Derouet, Dillon, Dreuw, Fujitani, Gatsios, Gearing, Gerhartz, Gobert, Grant, Grenier, Gupta, Guschin, Haan, Heinrich, Heinrich, Hermanns, Hermanns, Hibi, Hui, Ichihara, Kuropatwinski, Lacronique, Langdon, Li, May, Miles, Mosley, Nair, Nakamura, Nakamura, Peeters, Pezet, Pflanz, Quelle, Radtke, Richards, Schwaller, Smit, Sotiropoulos, Stahl, Stevenson, Stross, Tanaka, Vernallis, Wang, Wang   +53 more
core   +2 more sources

1,3-Dipolar cycloadditions of azomethine imines [PDF]

, 2015
Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen, Sansano, Jose M., Yus, Miguel   +2 more
core   +3 more sources

Synthesis and Anti‐Inflammatory Activity of Pyrazolines [PDF]

Journal of Chemistry, 2009
Some new pyrazoline derivatives were synthesized by reacting chalcones of 2‐acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti‐inflammatory activity. Some of these compounds showed moderate to considerable anti‐inflammatory activity.
B. Ramesh, T. Sumana
openaire   +2 more sources

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

European Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives

Applied Sciences, 2013
A series of new 1,3-diaryl-5-(1-phenyl-3-methyl-5-chloropyrazol-4-yl)-4,5-dihydropyrazole derivatives have been synthesized under sonication conditions in ethanol or methanol/glacial acetic acid mixture (5/1 ratio) with two equivalents of hydrazines and ...
Manuel Nogueras, Jairo Quiroga, Justo Cobo, Efraín Polo, Jorge Trilleras   +4 more
doaj   +1 more source

Recent advances in the synthesis and application of fluorescent α-amino acids [PDF]

, 2016
Fluorescence spectroscopy has become a powerful technique for probing a range of complex biological processes including enzyme mechanisms and protein-protein interactions. While the application of this technique uses a number of strategies, many of these
Harkiss, Alexander, Sutherland, Andrew
core   +1 more source

Quantification of Specific Urinary Oligosaccharide Biomarkers for Diagnosis and Treatment Monitoring of Alpha‐Mannosidosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Alpha‐mannosidosis (AM, OMIM# 248500), an ultra‐rare lysosomal storage disorder (LSD), is caused by insufficient activity of alpha‐mannosidase, an enzyme involved in degradation of N‐glycan oligosaccharides. Hence, specific oligosaccharides accumulate in tissues, resulting in a progressive multi‐organ disease.
Dominik Dörfel, Benjamin Dreyer, Mona Lindschau, Antonio Barbato, Nadia Altavilla, Giancarlo la Marca, Lara Maleen Marten, Friederike Bürger, Mara Botti, Lina Verena Sevenich, Ronen Spiegel, Anke Schumann, Melanie Herrmann, Davor Fielitz, Nicole Muschol, René Santer, Simona Murko   +16 more
wiley   +1 more source

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents

Molecules, 2018
The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole ring has been performed through a 1,3-dipolar cycloaddition reaction of N-thiocarbamoylpyrazoline and different hydrazonoyl halides or α-haloketones in the
Mastoura M. Edrees, Sraa Abu- Melha, Amirah M. Saad, Nabila A. Kheder, Sobhi M. Gomha, Zeinab A. Muhammad   +5 more
doaj   +1 more source

Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow

SynOpen, 2023
Pyrazolines and their pyrazole congeners are important heterocyclic building blocks with numerous applications in the fine chemical industries. However, traditional routes towards these entities are based on multistep syntheses generating substantial ...
Adam Burke, Silvia Spiccio, Mara Di Filippo, Marcus Baumann   +3 more
doaj   +1 more source