Results 61 to 70 of about 4,154 (224)

Sintesis Analog 4-bromo Pirazolin dari Kalkon Inti Naftalen dengan Katalis Asam dan Uji Aktivitas Nya sebagai Antibakteri [PDF]

, 2014
Pyrazolines have been reported to possess various biological activities such as antimicrobial, antidepressant, antidiabetic, anti-inflammatory, antipyretic, anticancer, and anticonvulsant activity. In this research, a halogenated pirazoline 5-(4-
Hariyanti, D. (Desy), Jasril, J. (Jasril), Teruna, H. Y. (Hilwan)   +2 more
core  

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source

Acetylcholinesterase inhibitory potencies of new pyrazoline derivatives [PDF]

Journal of Research in Pharmacy, 2020
Alzheimer's disease (AD) has no current cure and its mechanism is not fully known, but treatments for symptoms are available. Acetylcholinesterase (AChE) has been reported to be an applicable therapeutic target in patient with AD. Acetylcholinesterase inhibitors (AChEIs) are commonly used for it.
Tuğrak Sakarya, Mehtap, Gül, Halise İnci, Gülçin, İlhami   +2 more
openaire   +4 more sources

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Recent Advances in Carbonyl–Olefin and Carbonyl–Alkyne Metathesis Reactions

ChemistryEurope, Volume 4, Issue 4, April 2026.
Carbonyl–olefin and carbonyl–alkyne metathesis enable atom‐economic C–C bond formation beyond classical olefin metathesis. This review highlights recent advances in photochemical, Lewis‐acid, Brønsted‐acid, and organocatalytic strategies, mechanistic insights, and synthetic applications, showcasing carbonyl metathesis as a versatile platform for modern
Komal Kalonia, Ramees Komath, Martin Breugst   +2 more
wiley   +1 more source

Synthesis of a novel series of chalcones and pyrazolines, possessing indole with 4-(2,2,2-trifluroethoxy) pyridine moiety

Orbital: The Electronic Journal of Chemistry, 2012
A new method for the construction of novel fluorine-containing indole ring system has been reported. These indoles were converted into a new series of fluorine-containing indolyl chalcones (1a-g) and pyrazolines (2a-g). All the newly synthesized
Mazahar Farooqui, Nasir Ali Shafakat Ali, Afzal Yosuf Khan   +2 more
doaj   +1 more source

Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides [PDF]

, 2014
A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium.
Anbazhagan, S., Mathew, Bijo, Suresh, Jerad   +2 more
core  

Respirometric study of optical brighteners in textile wastewater [PDF]

, 2019
Optical brighteners (OBs) are colorless fluorescent dyes, widely used in industry to improve whiteness in materials. Nearly 80% of all OBs in the market are derivatives of stilbene.
Gutiérrez Bouzán, María Carmen, López Grimau, Víctor, Salas Olivares, Héctor Manuel, Vilaseca Vallvé, M. Mercedes   +3 more
core   +2 more sources

Unveiling the Anticancer Properties of New Synthesized Alkoxy‐ and Methyl Thio‐Chalcone Derivatives

Natural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Breast and cervical cancers are a serious problem and the leading cause of death in women in this decade. Chalcone is a promising compound with great potential for anticancer use. In this work, we synthesized six chalcone derivatives with alkoxy‐ and methylthio‐substituents through Claisen–Schmidt condensation at room temperature.
Nurcahyo Iman Prakoso, Taiki Umezawa, Dwiarso Rubiyanto, Azizah Zelia Kusumo, Fanny Septianingtyas, Muhamad Ikhsan Nurochman, Laras Kristianti, Salmahaminati, Pinus Jumaryatno, Minori Abe   +9 more
wiley   +1 more source

Synthesis of Some New Pyrazolines [PDF]

مجلة التربية والعلم, 2006
The present work includes the preparation of a series of substituted chalcones ( NO2 , Me , OMe , Cl ) and condensation of these chalcone with a series of prepared aromatic and aliphatic acid hydrazides in a basic medium to afford the new pyrazolines ...
A.J. AL-Hamdany, A.M. Hamdy
doaj   +1 more source