Synthesis and Crystal Structures of 4,5-Dihydroimidazo[1,5-b]pyrazol-6-ones
SynOpen, 2020 The synthesis of previously unattainable 2,5-disubstituted 4,5-dihydroimidazo[1,5-b]pyrazol-6-ones has been developed. Electrochemical reductions of readily available 2,2,2-trichloroethylideneacetophenones were followed by reaction with hydrazine ...
Antonio Guirado +6 more
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X-ray Structure of a (o-ga/acto-Pentaacetoxypentyl)pyrazoline [PDF]
, 1989 1-(3,5-Dimethyl-3-nitro-1-pyrazolin-4-yl) penta-0-acetyl-o-galacto-pentitol, e20H29N 3012, Mr= 503·5, orthorhombic, P21212¡, a= 14·471 (9), b = 14·518 (3), e= 12·028 (2) A, V= 2527·0 (1·7) A3, z = 4, Dx = 1·323 Mg m- 3, .A(Mo Ka)= 0·7107 A, J.
Conde Amiano, Alejandro +1 more
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 4, February 2026.ABSTRACT This research explored the potential of a synthesised pyrazoline derivative 5‐ethoxy 5‐hydroxy 3‐methyls 4, 5‐dihydro 1Hpyrazol 1 yl (pyridine 4 yl) methanone [5‐E‐5‐H‐PD], against arthritis using a Complete Freund's Adjuvant (CFA)‐induced arthritis in a rat model.
Jian Li +8 more
wiley +1 more source
Ferrocén-szubsztituált heterociklusok és származékaik szintézise, szerkezetigazolása és komplex spektroszkópiai vizsgálata = Synthesis, structure determination and complex spectroscopic study of ferrocene-substituted heterocycles and their derivatives [PDF]
, 2007 Új, mono- és poliheterociklusokkal egyszeresen és többszörösen szubsztituált ferrocénszármazékokat állítottunk elő. Szerkezetüket komplex nagyműszeres vizsgálatokkal (IR, MS, röntgendiffrakció, multinukleáris NMR) derítettük fel.
Csámpai, Antal +4 more
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Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.Dieser Mini‐Review behandelt die neuesten Fortschritte bei der Synthese, Reaktivität und metallfreien katalytischen Verwendung von mesoionischen N‐heterocyclischen Olefinen (mNHOs), Iminen (mNHIs), Thionen (mNHTs) und Phosphinidenen (mNHPs). Kurzzusammenfassung Übergangsmetallverbindungen sind allgemein für ihre Fähigkeit bekannt, kleine Moleküle zu ...
Subir Maji +3 more
wiley +1 more source
A Study of Antioxidant Properties and a Pharmacokinetic Investigation of Chalcones and Pyrazolines
Orbital: The Electronic Journal of ChemistryAntioxidant compounds are widely studied in the literature because they minimize oxidative damage in biological processes. In this context, chalcones and pyrazolines are considered prototype compounds for this purpose. This study describes the synthesis
André Luis Kerek +6 more
doaj +1 more source
2-Pyrazoline derivatives in neuropharmacology [PDF]
A novel series of 1,3,5-trisubstituted-2-pyrazoline derivatives (PFC-1 to PFC-16) were synthesized in a three step reaction using conventional and microwave assisted green chemistry approach.
Paliwal, Sarvesh +3 more
core +1 more source
Matrix Metalloproteinase Inhibition in Melanoma
Experimental Dermatology, Volume 35, Issue 1, January 2026.ABSTRACT Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix (ECM) and are found to participate in all stages of tumour progression including modifying signalling pathways, regulating cytokines and promoting tumour growth, particularly by inducing angiogenesis and facilitating cancer spread.
Ellie Zhang +2 more
wiley +1 more source
Synthesis, quantitative structure–property relationship study of novel fluorescence active 2-pyrazolines and application [PDF]
Royal Society Open Science, 2018 A variety of fluorescence-active fluorinated pyrazolines 13–33 was synthesized in good yields through cyclocondensation reaction of propenones 1–9 with aryl hydrazines 10–12.
Adel S. Girgis +5 more
doaj +1 more source
Sintesis Pirazolin dari Kalkon 3-kloro Inti Naftalen dan Uji Aktivitasnya sebagai Antibakteri [PDF]
, 2014 Pyrazolines have been reported to possess many of interesting biological activities such as antimicrobial, antidepressant, antitumor, antioxidant, antiinflammatory, anticancer and anticonvulsant activity .
Jasril, J. (Jasril) +2 more
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