Results 21 to 30 of about 5,173 (205)
A study on synthesis and antimicrobial activity of 4-acyl-pyrazoles
Journal of Saudi Chemical Society, 2018 4-Acyl-pyrazole-3-carboxylic acids (1) were synthesized via the reaction of 4-acyl-2,3-furandiones (F) with hydrazone (1-benzylidene-2-(2,5-dimethyl-phenyl)-hydrazine) by heating under solid phase and their acid chlorides (2) were obtained.
Adnan Çetin, İshak Bildirici
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Functionalization of diazines and benzo derivatives through deprotonated intermediates. [PDF]
, 2008 International audienceThis critical review targets as a readership researchers generally oriented toward organic synthesis and in particular those active in heterocyclic chemistry.
Chevallier, Floris, Mongin, Florence
core +2 more sources
Safe Synthesis of 4,7-Dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine and Its SNAr Reactions
Molecules, 2018 A safe and efficient synthesis of 4,7-dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine from the commercial diaminomaleonitrile is reported. Conditions for selective aromatic nucleophilic substitution of one or two bromine atoms by oxygen and nitrogen ...
Timofey N. Chmovzh +4 more
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Angewandte Chemie, EarlyView.Photocatalytic cross‐coupling: A redox‐neutral photochemical method enables direct C(sp2)─C(sp2) bond formation between phenols and heteroaryl halides using an organic dye and base. Complementary radical generation allows efficient cross‐coupling in up to 91% yield. Mechanistic studies, DFT, HTE, and machine learning rationalize and predict reactivity,
Matthew C. Carson +4 more
wiley +2 more sources
Construction of Unusual Indole-Based Heterocycles from Tetrahydro-1H-pyridazino[3,4-b]indoles
Molecules, 2020 Herein, we report the successful syntheses of scarcely represented indole-based heterocycles which have a structural connection with biologically active natural-like molecules.
Cecilia Ciccolini +5 more
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Single crystal X-ray structure of 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile [PDF]
, 2013 The title compound 3-amino-5-(4-chlorophenyl)pyridazine-4-carbonitrile was prepared by a one-pot three-component reaction of malononitrile with corresponding arylglyoxal in the presence of hydrazine hydrate at room temperature in water and ethanol.
Ahmad Poursattar Marjani +3 more
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Microdroplet Stabilization Enabled Direct Mass Spectrometric Identification of Electrogenerated Transient Carbocation Intermediates. [PDF]
Adv Sci (Weinh)The in situ mass spectrometric identification of the electrogenerated benzylic and phenylic carbocations, whose half‐lives in bulk solutions are on the nanosecond scale, is achieved by taking advantage of the unique stabilization effect of the electrosprayed microdroplets.
Zhu GS, Hui RJ, Hu J.
europepmc +2 more sources
Tandem mass spectrometric study of annelation isomers of the novel thieno[3',2':4,5]pyrido[2,3-d]pyridazine ring system [PDF]
, 2014 In the present communication, we describe tandem combinations of Suzuki - condensation ring closure reactions to obtain a novel thieno[3 -,2 -:4,5]pyrido[2,3-d]pyridazine ring system. These compounds were studied by tandem mass spectrometry in detail and
Krajsovszky, Gábor +2 more
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International Journal of Electrochemical Science, 2020 The present study theoretically investigates the molecular properties of two pyridazine derivatives (5-benzyl-6-methyl pyridazine-3-one, PO and 5-benzyl-6-methyl pyridazine-3-thione, PS) using quantum chemical technique (Parameterization Method 3). It is
Ubong Eduok
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Novel Ring Systems: Spiro[Cycloalkane] Derivatives of Triazolo- and Tetrazolo-Pyridazines
Molecules, 2021 In orderto synthesize new pyridazine derivatives anellated with different nitrogen heterocyclic moieties, spiro[cycloalkane]pyridazinones were transformed into the corresponding thioxo derivatives via a reaction with phosphorus pentasulfide. The reaction
Csilla Sepsey Für +6 more
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