Results 41 to 50 of about 5,173 (205)

2-Methyl-6-(4-aminophenyl)-4,5-dihydro-3(2H)-pyridazinone Synthon for Some New Annelated 1,2,3-Selena/Thiadiazoles and 2H-Diazaphospholes with Anticipated Biological Activity and Quantum Chemical Calculations

Molecules, 2023
A convenient and efficient synthetic protocol for the new selenadiazole. Thiadiazole and diazaphosphole derivatives incorporating a pyridazine moiety originating from 4-(4-aminophenyl)-4-oxobutanoic acid (1) were described.
I. E. El-Shamy, E. Hleli, M. A. El-Hashash, I. Kelnar, A. M. Abdel-Mohsen   +4 more
doaj   +1 more source

A Hyperpolarizable 1H Magnetic Resonance Probe for Signal Detection 15 Minutes after Spin Polarization Storage [PDF]

, 2016
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are two extremely important techniques with applications ranging from molecular structure determination to human imaging.
Adams, Ardenkjaer-Larsen, Ardenkjaer-Larsen, Asif, Bhattacharya, Bhattacharya, Bowers, Carravetta, Day, Eisenberg, Eshuis, Feiweier, Franzoni, Golman, Heinisch, Hovener, Kurhanewicz, Levitt, Marco-Rius, Mewis, Natterer, Olaru, Roy, Salvi, Stevanato, Tayler, Theis, Theis, Warren, Zeng, Zhang   +30 more
core   +1 more source

Effect of New Synthesised Pyridazine Derivatives on the Electrochemical Behaviour of Mild Steel in 1M HCl Solution: Part-1

International Journal of Electrochemical Science, 2012
The effect of adding new pyridazine derivatives, ethyl [4-(2-chlorobenzyl)-3-methyl-6-oxopyridazin-1(6H)-yl]acetate (P1), ethyl [4-(2-chlorobenzyl)-3-methyl-6-thioxopyridazin-1(6H)-yl]acetate (P2), 5-(2-chlorobenzyl)-2-(2-hydroxyethyl)-6-methylpyridazin ...
B. Zerga, R. Saddik, B. Hammouti, M. Taleb, M. Sfaira, M. Ebn Touhami, S.S. Al-Deyab, N. Benchat   +7 more
doaj   +1 more source

Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties

Molecules, 2023
Synthetic unnatural base pairs have been proven to be attractive tools for the development of DNA-based biotechnology. Our group has very recently reported on alkynylated purine–pyridazine pairs, which exhibit selective and stable base-pairing via ...
Hidenori Okamura, Giang Hoang Trinh, Zhuoxin Dong, Wenjue Fan, Fumi Nagatsugi   +4 more
doaj   +1 more source

Transforming LiTMP lithiation of challenging diazines via gallium alkyl trans-metal-trapping [PDF]

, 2016
This study establishes a new trans-metal-trapping (TMT) protocol based on a mixture of LiTMP (the base) and tris(trimethylsilylmethyl)gallium [Ga(CH2SiMe3)3, GaR3] (the trap) that, operating in a tandem manner, is effective for the regioselective ...
Hevia, Eva, Kennedy, Alan R., Mulvey, Robert E., Uzelac, Marina   +3 more
core   +1 more source

Hydrogen Bonding is Key Factor in Reversible NH3 Uptake Causing Vapochromic and Magnetochemical Switching in Ni(II) Paddlewheel Complexes

ChemistryEurope, EarlyView.
Nickel complexes showing reversible vapochromic and spin crossover behaviors upon coordination and release of NH3 were synthesized. They bear bidentate pyridazine ligands, which allows for formation of hydrogen bonds between NH3 and the ligand in the second coordination sphere.
Sebastian Rücker, Jörg A. Schachner, Sergey M. Borisov, Ferdinand Belaj, Silvia Carlotto, Lidia Armelao, Antoine Dupé, Nadia C. Mösch‐Zanetti   +7 more
wiley   +1 more source

Study On Synthesis and Biological Activity of Some Pyridopyridazine Derivatives

Acta Chimica Slovenica, 2018
In this study, new pyrido[3,4-d]pyridazine derivatives were synthesized and evaluated for their in vitro antibacterial, antifungal and antimycobacterial activities.
Sevilay Akçay, Mahmut Ülger, Fatma Kaynak Onurdağ, Yasemin Dündar   +3 more
doaj   +1 more source

Impact of a pyridazine derivative on tripartite synapse ultrastructure in hippocampus: a three-dimensional analysis

Frontiers in Cellular Neuroscience, 2023
IntroductionWe previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer’s disease.
Zan Xu, Joshua B. Foster, Rashelle Lashley, Xueqin Wang, Emily Benson, Grahame Kidd, Chien-liang Glenn Lin   +6 more
doaj   +1 more source

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Microwave Assisted Reactions of Fluorescent Pyrrolodiazine Building Blocks

Molecules, 2019
We report here the synthesis and optical spectral properties of several new pyrrolodiazine derivatives. The luminescent heterocycles were synthesized by 1,3-dipolar cycloaddition reactions between N-alkylated pyridazine and methylpropiolate or dimethyl ...
Costel Moldoveanu, Dorina Amariucai-Mantu, Violeta Mangalagiu, Vasilichia Antoci, Dan Maftei, Ionel I. Mangalagiu, Gheorghita Zbancioc   +6 more
doaj   +1 more source