Results 71 to 80 of about 5,173 (205)

Investigation of furo[2,3-h]- and pyridazino[3,4-f]cinnolin-3-ol scaffolds as substrates for the development of novel HIV-1 integrase inhibitors [PDF]

, 2011
With the aim to develop novel HIV-1 integrase inhibitors, we obtained a set of condensed ring systems based on the furo[2,3-h]cinnolin-3(2H)-one and pyridazino[3,4-f]cinnolin-3-ol scaffolds bearing a potential chelating pharmacophore, which can be ...
Casule, Paola, Derudas, Marco, El-Tamany, El-Sayed H, Gomaa, Mohamed F Y, Hasanen, Jehan Abd-Elrazik, Mariani, Alberto, Pala, Nicolino, Sechi, Mario   +7 more
core   +1 more source

π‐Expanded Nitrogen‐Cation (N+)‐Doped Polycyclic Aromatic Hydrocarbons: A Review of Intramolecular Cyclization Routes to Benzo[c]Quinolizinium, Triazinium, Pyridoquinazolinium, and Pyridoquinoxalinium Frameworks

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro, Cyrille Monnereau, Laure Guy   +2 more
wiley   +1 more source

3,6-Dibromopyridazine-4,5-diamine

Molbank, 2019
Dihalogenated derivatives of 1,2,5-chalcogenadiazoles fused with benzene or heterocyclic rings are of interest as starting compounds for photovoltaic materials.
Timofey N. Chmovzh, Ekaterina A. Knyazeva, Olga O. Ustimenko, Oleg A. Rakitin   +3 more
doaj   +1 more source

Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters

Angewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
The intracellular delivery of trans‐cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron‐demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro) strategy. Once hydrolyzed inside cells, the modified uridines and cytidines are metabolically incorporated into nascent RNA, are labelled by a dual ...
J. Iven H. Knaack, Eileen List, Dörte Stalling, Vincente T. Sterrenberg, Chris Meier, Hans‐Achim Wagenknecht, Jens B. Bosse   +6 more
wiley   +1 more source

Utility of N-2-pyridyl-3-oxobutanamide in heterocyclic synthesis: Synthesis of new dihydropyridine, fused pyridine, pyridopyridine, pyridazine and pyridopyrimidinethione derivatives [PDF]

, 2010
2-Aminopyridine was fused with ethyl acetoacetate without solvent for two hours to yield the  N-2-pyridyl–3-oxobutanamide 1. However, when the reaction time was increased to 5 hours a structure 3 was obtained.
Abdel Hafiz, I., Baker, Safaa, Hussein, A.   +2 more
core  

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Microwave Assisted Condensation Reactions of 2-Aryl Hydrazonopropanals with Nucleophilic Reagents and Dimethyl Acetylenedicarboxylate

Molecules, 2007
The reaction of methyl ketones 1a-g with dimethylformamide dimethylacetal (DMFDMA) afforded the enaminones 2a-g, which were coupled with diazotized aromatic amines 3a,b to give the corresponding aryl hydrazones 6a-h.
Rita M. Borik, Khadijah M. Al-Zaydi
doaj   +1 more source

Reactions of pyridazines and pyridazine 1-oxides with nitrogen-containing nucleophiles [PDF]

In dit proefschrift is een orienterend onderzoek beschreven naar het chemisch gedrag van halogeen-pyridazinen en halogeen-pyridazine-N-oxiden met kaliumamide in vloeibare ammoniak, met methanolische ammoniak en met vloeibare ammoniak. Dit onderzoek hangt
Klinge, D.E.
core   +1 more source

Encapsulated pyridazine Cr(III) complexes prepared from biosorbents supported in zeolites [PDF]

, 2005
The encapsulation of a pyridazine Cr(III) complex was prepared from a robust biosorption system consisting of a bacterial biofilm supported on NaY or NaX zeolites. The maximum removal efficiency was 20% for Cr in both systems based in NaY or NaX.
Figueiredo, Hugo, Fonseca, A. Maurício C., Neves, Isabel C., Quintelas, C., Raposo, M. Manuela M., Tavares, M. T.   +5 more
core   +2 more sources

Pyridazine Derivatives. IV. The Structures of Aminopyridazines.

Chemical and Pharmaceutical Bulletin, 1963
The infrared absorption spectra of the two aminopyridazines were observed and compared with those of the three aminopyridines and aniline. The amino-form of the two aminopyridazines was confirmed, and at the same time the structural similarity of 4-aminopyridazine with 4-aminopyridine was shown by their infrared spectra.
Y, NITTA, R, TOMII, F, YONEDA
openaire   +3 more sources