Results 91 to 100 of about 12,861 (208)

Microbial−mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations [PDF]

, 2013
Understanding the metabolic processes associated with aging is key to developing effective management and treatment strategies for age-related diseases. We investigated the metabolic profiles associated with age in a Taiwanese and an American population.
Beckonert O., Bell J. D., Cannon J. G., Carmel R., Carol D. Ryff, Chadeau-Hyam M., Cho S., Christopher L. Coe, Clarke R., Coe C. L., Dana A. Glei, Davies K. M., Dean M., Elaine Holmes, Elsden S. R., Fukushima T., Goldman N., Hammar M. L., He F., Hebuterne X., Hehemann J. H., Holmes E., Hopkins M. J., Houtkooper R. H., Hurley B. F., Jeremy K. Nicholson, Jonathan R. Swann, Kaiser L. G., Kochhar S., Konstantina Spagou, Laidlaw S. A., Mariat D., Marmot M. G., Matthew Lewis, Maxine Weinstein, Mishur R. J., Muangpaisan W., Nicholson J. K., Noreen Goldman, Okuda Y., O’Sullivan O., Partridge L., Perrone R. D., Piper M. D., Psihogios N. G., Ramakrishna B. S., Ramakrishna B. S., Regitz-Zagrosek V., Robert L., Saude E. J., Slupsky C. M., Stanley E. G., Takiyama N., Teresa E. Seeman, Tiihonen K., Triantafyllou K., van den Bussche H., Veselkov K. A., Veselkov K. A., Vukovich M. D., Wald A., Walston J., Wang Y., Wang Z., Want E. J., Welshman S. G., Wijeyesekera A., Willets J. M., Williams A., Wolfe R. R., Yap I. K., Yasuda M., Zhang A. Q., Zhang F.   +73 more
core   +1 more source

Crystal structures of three hydrogen-bonded 1:2 compounds of chloranilic acid with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine

Acta Crystallographica Section E: Crystallographic Communications, 2017
The crystal structures of the 1:2 compounds of chloranilic acid (systematic name: 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone) with 2-pyridone, 3-hydroxypyridine and 4-hyroxypyridine, namely, bis(2-pyridone) chloranilic acid, 2C5H5NO·C6H2Cl2O4, (I), bis ...
Kazuma Gotoh, Hiroyuki Ishida
doaj   +1 more source

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

International Journal of Cosmetic Science, Volume 48, Issue 1, Page 1-15, February 2026.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin, Béatrice Le Varlet, Claire Regazzetti, Thierry Passeron, Jinhua Wang, David E. Fisher, Philippe Schaison, Braham Shroot   +7 more
wiley   +1 more source

Acceleration of hemiacetal cleavage through hydrogen bonding : a new synthetic catalyst with balanced conformational flexibility and preorganization [PDF]

, 1991
Hemiacetal cleavage catalyst 1 was designed, synthesized, and shown to be effective in promoting glycolaldehyde dimer dissociation and tetramethylglucose ...
Bartoletti M., Gennari C., Molinari F., PIARULLI, UMBERTO, Potenza D.   +4 more
core   +1 more source

Supramolecular Potential of Vanadium β-Diketonate and Picolinate Compounds and The First One-dimensional Oxidovanadium(IV) Complex with β-Diketonate Ligand

Acta Chimica Slovenica, 2014
Three vanadium compounds with β-diketonato or picolinato ligands were prepared and structurally characterized. In compounds [VO(tfpb)2]∞ (1) (tfpb = 4,4,4-trifluoro-1-phenylbutane-1,3-dionate) and [VO(acac)2(2-pyridone)] (2) the coordination of vanadium ...
Tanja Koleša Dobravc, Anton Meden, Franc Perdih   +2 more
doaj   +1 more source

SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. [PDF]

, 2017
Pericyclic reactions-which proceed in a concerted fashion through a cyclic transition state-are among the most powerful synthetic transformations used to make multiple regioselective and stereoselective carbon-carbon bonds.
Chen, Mengbin, Hai, Yang, Houk, KN, Liu, Fang, Ohashi, Masao, Sato, Michio, Tang, Man-Cheng, Tang, Yi, Watanabe, Kenji, Yang, Zhongyue   +9 more
core   +1 more source

Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor [PDF]

, 2019
Nicotinic acetylcholine receptors (nAChRs) are crucial for communication between synapses in the central nervous system. As such, they are also implicated in several neuropsychiatric and addictive diseases.
Blom, Annet E. M., Dougherty, Dennis A., Gallagher, Timothy, Lester, Henry A., Rego Campello, Hugo   +4 more
core   +4 more sources

Nickel‐Catalyzed cine‐Substitution Toward Carbonyl Dance

Chemistry – An Asian Journal, Volume 21, Issue 1, January 2026.
A nickel‐catalyzed cine‐substitution enables a 1,2‐carbonyl translocation (“carbonyl dance”) at tetralone derivatives under mild conditions. This transformation proceeds through enolization and selective amination, followed by hydrolysis, to afford β‐tetralones bearing migrated carbonyl groups.
Eito Moriya, Kei Muto, Junichiro Yamaguchi   +2 more
wiley   +1 more source

Rapid changes in Atlantic grey seal milk from birth to weaning – immune factors and indicators of metabolic strain [PDF]

, 2017
True seals have the shortest lactation periods of any group of placental mammal. Most are capital breeders that undergo short, intense lactations, during which they fast while transferring substantial proportions of their body reserves to their pups ...
Bawazeer, Sami, Burchmore, Richard J.S., Kennedy, Malcolm W., Lowe, Amanda D., McGill, Suzanne, Pomeroy, Patrick, Watson, David G.   +6 more
core   +3 more sources

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions [PDF]

, 2018
Kirromycin is the main product of the soil-dwelling Streptomyces collinus Tü 365. The elucidation of the biosynthetic pathway revealed that the antibiotic is synthesised via a unique combination of trans-/cis-AT type I polyketide synthases and non ...
Ding, Ling, Grond, Stephanie, Hofeditz, Torben, Laiple, Kristina J., Lee, Sang Yup, Musiol-Kroll, Ewa M., Robertsen, Helene L., Weber, Tilmann, Wohlleben, Wolfgang   +8 more
core   +2 more sources