Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate
International Journal of Nanomedicine, 2012 Bioconjugates of a polyamidoamine (PAMAM) G3 dendrimer and an aldehyde were synthesized as carriers for vitamins A and B₆, and the bioavailability of these vitamins for skin nutrition was investigated.Nuclear magnetic resonance (NMR) and ultraviolet-visible methods were used to characterize the structure of the bioconjugates and for monitoring release ...
Stanisław Wołowiec +1 more
openaire +6 more sources
Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. [PDF]
, 2015 BackgroundIt is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage.
Cooper, Arthur JL +8 more
core +2 more sources
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
細胞プロファイリングシステムを用いた細胞、組織製品の特性解析 [PDF]
, 2019 博士(医学) 甲第687号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Ayako Tominaga・Masato Sato・Takumi Takahashi・Eriko Toyoda・Kenichi Toyoda・Takashi Suzuki・Masatoshi Takahashi・Masahiko Watanabe・Ken Okazaki，タイトル:Quality assessment of cellular and tissue-based products using liquid ...
冨永 絢子
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Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools. [PDF]
, 2016 This review discusses the use of molecular modeling tools, together with existing experimental findings, to provide a complete atomic-level description of enzyme dynamics and function.
Chang, Chia-En A +3 more
core +2 more sources
An Antihemolytic Action of Pyridoxal.
Experimental Biology and Medicine, 1954 SummaryPretreatment of erythrocytes with 10 mM pyridoxal makes the cells subsequently more resistant to lysis by hypotonic solutions. Indoleacetic acid shows the same behavior to a smaller degree. These effects are attributed to a net loss of cell solutes in the form of potassium and chloride which the agents produce.
Halvor N. Christensen +2 more
openaire +3 more sources
The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]
, 2009 Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Carson, Ray J. +4 more
core +5 more sources
Microbiome Single Cell Atlases Generated with a Commercial Instrument
Advanced Science, EarlyView.Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li +8 more
wiley +1 more source
Competition of Pyridoxal 5'-Phosphate with Ribulose 1,5-Bisphosphate and Effector Sugar Phosphates at the Reaction Centers of the Spinach Ribulose 1,5-Bisphosphate Carboxylase/Oxygenase [PDF]
, 1980 The Stimulation of the carboxylase reaction by effectors of ribulose 1,5-bisphosphate carboxyl ase/oxygenase displays higher sensitivity towards pyridoxal 5'-phosphate inhibition than the catalytical process itself. Pyridoxal 5'-phosphate binding to the
Gaudszun, Thomas +3 more
core +1 more source
Applied Artificial Intelligence in Materials Science and Material Design
Advanced Intelligent Systems, EarlyView.AI‐driven methods are transforming materials science by accelerating material discovery, design, and analysis, leveraging large datasets to enhance predictive modeling and streamline experimental techniques. This review highlights advancements in AI applications across spectroscopy, microscopy, and molecular design, enabling efficient material ...
Emigdio Chávez‐Angel +7 more
wiley +1 more source