Results 31 to 40 of about 5,366 (188)

A Potent Polymer/Pyridoxamine Enzyme Mimic

, 2016
An enzyme mimic consisting of pyridoxamines covalently linked to polyethyleneimine carrying long-chain alkyl groups converts pyruvic acid to dl-alanine with as much as an 8000-fold acceleration relative to the reaction with simple pyridoxamine at the ...
Ronald Breslow (1835350), Lei Liu (5074)
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The Effect of Pyridoxamine on Large Artery Stiffening and Brain Oxidative Stress and Inflammation with Age [PDF]

, 2019
39 pagesAs people age, large elastic arteries become stiffer and cerebral arteries become dysfunctional. This research sought to determine whether treatment with pyridoxamine, a form of vitamin B6, prevents age-related arterial stiffening by limiting the
Kronquist, Elise Kendall
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Pyridoxamine Limits Mitochondria-Dependent Ferroptosis in a Rat Model of Doxorubicin-Induced Cardiotoxicity

, 2023
15199: Pyridoxamine Limits Mitochondria-Dependent Ferroptosis in a Rat Model of Doxorubicin-Induced Cardiotoxic… https://www.ahajournals.org/doi/abs/ Abstract Background: The use of doxorubicin (DOX) chemotherapy is limited by cardiotoxicity ...
BITO, Virginie, WOLFS, Esther, DELUYKER, Dorien, HAESEN, Sibren, VERGHOTE, Eline, Delaet, Anouk   +5 more
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Pyridoxamine Attenuates Doxorubicin-Induced Cardiomyopathy without Affecting Its Antitumor Effect on Rat Mammary Tumor Cells

Cells
Doxorubicin (DOX) is commonly used in cancer treatment but associated with cardiotoxicity. Pyridoxamine (PM), a vitamin B6 derivative, could be a cardioprotectant.
Sibren Haesen, Eline Verghote, Ellen Heeren, Esther Wolfs, Dorien Deluyker, Virginie Bito   +5 more
doaj   +1 more source

Dietary Reference Values for vitamin B6

EFSA Journal, 2016
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derives Dietary Reference Values (DRVs) for vitamin B6. The Panel considers that plasma pyridoxal 5′‐phosphate (PLP) concentration is the
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Biosynthesis of food constituents: Vitamins. 2. Water-soluble vitamins: Part 1 - a review

Czech Journal of Food Sciences, 2007
This review article gives a survey of the generally accepted biosynthetic pathways that lead to water-soluble vitamins in microorganisms, plants and some animals.
Jan Velíšek, Karel Cejpek
doaj   +1 more source

The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model. [PDF]

PLoS ONE, 2013
BACKGROUND: Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6.
Monique Albersen, Marjolein Bosma, Nine V V A M Knoers, Berna H B de Ruiter, Eugène F Diekman, Jessica de Ruijter, Wouter F Visser, Tom J de Koning, Nanda M Verhoeven-Duif   +8 more
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Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice

, 2023
Methylglyoxal (MGO) is a reactive glucose metabolite linked to diabetic cardiovascular disease (CVD). MGO levels surge during intermittent hyperglycemia.
Wouters, K., Murphy, A.J., Wouters, K.; id_orcid, Block, T., Tikellis, C., Schalkwijk, C.G.; id_orcid, Thomas, M.C., Hanssen, N.M.J., Miyata, T., Cooper, M.E., Schalkwijk, C.G., Dragoljevic, D., Lee, M.K.S., Scheijen, J.L.J.M., Scheijen, J.L.J.M.; id_orcid, Pickering, R.J.   +15 more
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Impact of Dissolved Oxygen during UV-Irradiation on the Chemical Composition and Function of CHO Cell Culture Media.

PLoS ONE, 2016
Ultraviolet (UV) irradiation is advantageous as a sterilization technique in the biopharmaceutical industry since it is capable of targeting non-enveloped viruses that are typically challenging to destroy, as well as smaller viruses that can be difficult
Sarah M Meunier, Biljana Todorovic, Emma V Dare, Afroza Begum, Simon Guillemette, Andrew Wenger, Priyanka Saxena, J Larry Campbell, Michael Sasges, Marc G Aucoin   +9 more
doaj   +1 more source

Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet-Induced Kidney Dysfunction [PDF]

, 2017
Pyridoxamine, a structural analog of vitamin B6 that exerts antiglycative effects, has been proposed as supplementary approach in patients with initial diabetic nephropathy.
Nigro, D, Mastrocola, R, V. Bitonto, M. Aragno, D. Collotta, G. Rosa, F. Baratta, M. Collino, Aragno, M, J. C. Cutrin, ROSA, GIANLUCA, D. Nigro, Cento, A. S, Collotta, D, Collino, M., Cutrin, J. C, F. Chiazza, A. S. Cento, R. Mastrocola, Bitonto, V, Chiazza, F, Baratta, F   +21 more
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