Results 21 to 30 of about 4,298 (230)
Molecular Metabolism, 2019 Objective: The impact of diabetes mellitus on the central nervous system is less widely studied than in the peripheral nervous system, but there is increasing evidence that it elevates the risk of developing cognitive deficits.
Sarah Kassab +12 more
doaj +1 more source
Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy
Journal of Diabetes Research, 2016 Objective. Diabetic nephropathy is a life-threatening complication in patients with long-standing diabetes. Hemodynamic, inflammatory, and metabolic factors are considered as developmental factors for diabetic nephropathy.
Tarek Kamal Abouzed +7 more
doaj +1 more source
Molecules, 2018 [13C3]-labelled vitamers (PN, PL and PM) of the B6 group were prepared starting from [13C3]-propionic acid. [13C3]-PN was synthesized in ten linear steps with an overall yield of 17%.
Thomas Bachmann, Michael Rychlik
doaj +1 more source
Frontiers in Pharmacology, 2019 Neonatal epileptic encephalopathy (NEE), as a result of pyridoxine 5′-phosphate oxidase (PNPO) deficiency, is a rare neural disorder characterized by intractable seizures and usually leads to early infant death.
Po-Yuan Chen +5 more
doaj +1 more source
All-enzymatic HPLC method for determination of individual and total contents of vitamin B6 in foods
Food & Nutrition Research, 2012 Background : There is a need for a reliable and accurate method for quantification of each of the seven individual vitamin B6 compounds including pyridoxine-β-glucoside in foods.
Huong Thi Viet Do +3 more
doaj +1 more source
Asymmetric biomimetic transamination of α-keto amides to peptides
Nature Communications, 2021 Asymmetric transamination of α-keto amides could provide an efficient strategy to synthesise peptides, but has not been well developed yet. Here, the authors design chiral pyridoxamine catalyst and realize the asymmetric biomimetic transamination of α ...
Weiqi Cai +7 more
doaj +1 more source
Molecules, 2014 The purpose of this study was to examine the application of the coordinated cis-[Cr(C2O4)(pm)(OH)2]+ cation where pm denotes pyridoxamine, as a specific sensing ion for the detection of hydrogen peroxide (H2O2).
Dagmara Jacewicz +5 more
doaj +1 more source
Molecules, 2020 Water-soluble vitamins like B3 (nicotinamide), B6 (pyridoxine), and B9 (folic acid) are of utmost importance in human health and disease, as they are involved in numerous critical metabolic reactions. Not surprisingly, deficiencies of these vitamins have
Ghada Rashad Ibrahim +5 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Biointegrated Battery‐Based Electroceuticals
Advanced Materials, EarlyView.Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou +6 more
wiley +1 more source