Results 11 to 20 of about 5,366 (188)
Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy [PDF]
Journal of Diabetes Research, 2016 Objective. Diabetic nephropathy is a life-threatening complication in patients with long-standing diabetes. Hemodynamic, inflammatory, and metabolic factors are considered as developmental factors for diabetic nephropathy.
Tarek Kamal Abouzed +7 more
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Reduction of Methylglyoxal-Induced Glycation by Pyridoxamine Improves Adipose Tissue Microvascular Lesions [PDF]
Journal of Diabetes Research, 2013 Background and Aims. Adipose tissue dysfunction results from many factors, including glycation-induced microvascular damages. We tested the usefulness of inhibiting methylglyoxal-induced glycation to adipose tissue microvasculature in this work, using ...
Tiago Rodrigues +4 more
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Repurposing pyridoxamine for therapeutic intervention of intravascular cell-cell interactions in mouse models of sickle cell disease [PDF]
Haematologica, 2019 Adherent neutrophils on vascular endothelium positively contribute to cell-cell aggregation and vaso-occlusion in sickle cell disease. In the present study, we demonstrated that pyridoxamine, a derivative of vitamin B6, might be a therapeutic agent to ...
Jing Li +7 more
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Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation [PDF]
Molecular Metabolism, 2019 Objective: The impact of diabetes mellitus on the central nervous system is less widely studied than in the peripheral nervous system, but there is increasing evidence that it elevates the risk of developing cognitive deficits.
Sarah Kassab +12 more
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Effect of dyes on the photodecomposition of pyridoxine and pyridoxamine
Journal of Pharmacy and Pharmacology, 1981 Abstract Erythrosine, eosine Y, rose bengal, mercurochrome, methylene blue, azure A and azure B accelerated the photodecomposition of pyridoxine and pyridoxamine at pH 5–9, but fluorescein and acid red did not. The photodecomposition of pyridoxine in the presence of erythrosine was greatest at pH 9·0, The singlet oxygen generated by ...
N, Mizuno, A, Fujiwara, E, Morita
openaire +3 more sources
Molecular Pain, 2020 Diabetic neuropathic pain is a common complication of diabetes mellitus and requires a substantial amount of societal resources. Pyridoxamine is an inhibitor of advanced glycation and lipoxidation end products.
Xin Zhang +5 more
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B6 vitamers as generators and scavengers of reactive oxygen species
Journal of Photochemistry and Photobiology, 2021 B6 vitamers are important natural compounds for human life, principally for amino acid metabolism, and have been reported as potent scavenger molecules of both endogenous and exogenous reactive oxygen species (ROS).
Italo Rodrigo Calori +2 more
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Scientific opinion on the tolerable upper intake level for vitamin B6
EFSA Journal, 2023 Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the tolerable upper intake level (UL) for vitamin B6.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) +20 more
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Antioxidants, 2021 Recent studies have shown that carbonyl stress is a causative factor of schizophrenia, categorized as carbonyl stress-related schizophrenia (CS-SCZ).
Shin Koike +8 more
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Prebiotic Synthesis of Aspartate Using Life’s Metabolism as a Guide
Life, 2023 A protometabolic approach to the origins of life assumes that the conserved biochemistry of metabolism has direct continuity with prebiotic chemistry. One of the most important amino acids in modern biology is aspartic acid, serving as a nodal metabolite
Stuart A. Harrison +3 more
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