Results 21 to 30 of about 5,110,049 (220)

Vitamin B-6 Status Indices Are Lower in Pregnant than in Nonpregnant Women but Urinary Excretion of 4-Pyridoxic Acid Does Not Differ

Journal of NutriLife, 1993
The cause of reduced plasma pyridoxal-5'-phosphate (PLP) concentration and the validity of plasma PLP concentration as a vitamin B-6 status indicator during pregnancy are not well understood.
Paula R. Trumbo, Jing Wen Wang
openalex   +2 more sources

Identification and impact of microbiota-derived metabolites in ascites of ovarian and gastrointestinal cancer [PDF]

Cancer & Metabolism
Background Malignant ascites is a common complication of advanced ovarian cancer (OC) and gastrointestinal cancer (GI), significantly impacting metastasis, quality of life, and survival.
Sisi Deng, Wooyong Kim, Kefan Cheng, Qianlu Yang, Yogesh Singh, Gyuntae Bae, Nicolas Bézière, Lukas Mager, Stefan Kommoss, Jannik Sprengel, Christoph Trautwein   +10 more
doaj   +2 more sources

Associations between systemic inflammation and cognitive trajectories post-stroke [PDF]

Scientific Reports
Our objective was to explore whether plasma inflammatory biomarkers and related metabolites in acute phase and 3 months after stroke were associated with different cognitive trajectories and with changes in cognition post-stroke.
Heidi Vihovde Sandvig, Ingvild Saltvedt, Trine Holt Edwin, Stina Aam, Katinka Nordheim Alme, Rannveig Sakshaug Eldholm, Stian Lydersen, Tom Eirik Mollnes, Ragnhild Munthe-Kaas, Per Magne Ueland, Arve Ulvik, Torgeir Wethal, Anne-Brita Knapskog   +12 more
doaj   +2 more sources

Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner [PDF]

Gut Microbes
Chronic stress can result in various conditions, including psychological disorders, neurodegenerative diseases, and accelerated brain aging. Gut dysbiosis potentially contributes to stress-related brain disorders in individuals with chronic stress ...
Wenxiang Qing, Huimin Chen, Xin Ma, Jie Chen, Yuan Le, Hui Chen, Jianhua Tong, Kaiming Duan, Daqing Ma, Wen Ouyang, Jianbin Tong   +10 more
doaj   +2 more sources

Vitamin B6 Group. XV. Urinary Excretion of Pyridoxal, Pyridoxamine, Pyridoxine, and 4-Pyridoxic Acid in Human Subjects.

Experimental Biology and Medicine, 1949
SummaryThe known metabolic products of vitamin B6—pyridoxal, pyridoxamine, pyridoxine and pyridoxic acid—were measured in normal human urine and in the urine of human subjects each fed one of the 3 forms of the vitamin.The chief product found, regardless of the form fed, was pyridoxic acid.
J C, RABINWITZ, E E, SNELL
openaire   +3 more sources

Metabolic dynamics and stage-specific biomarkers in chronic HBV infection: a metabolomics study [PDF]

BMC Gastroenterology
Objective This study was aimed to identify and investigate changes in serum metabolites across the natural progression of chronic hepatitis B (CHB) patients, discover differential metabolites and metabolic pathways in different disease phases, and ...
Lizhi Liu, Zifei Zhu, Wenwen Jin, Xi Su, Zhonghua Deng, Cunyan Li   +5 more
doaj   +2 more sources

Evaluation of Adefovir PBPK Model to Assess Biomarker‐Informed OAT1 Drug–Drug Interaction and Effect of Chronic Kidney Disease

CPT: Pharmacometrics & Systems Pharmacology
Evaluation of transporter‐mediated drug–drug interactions (DDI) with endogenous biomarkers, coupled with physiologically‐based pharmacokinetic modeling (PBPK) is envisioned to replace or reduce dedicated DDI clinical trials with clinical probe substrates.
Shawn Pei Feng Tan, Huaying Wu, Amin Rostami‐Hodjegan, Daniel Scotcher, Aleksandra Galetin   +4 more
doaj   +2 more sources

A Microprocedure for the Determination of 4-Pyridoxic Acid in Urine [PDF]

Clinical Chemistry, 1964
Muriel J Woodring, Dorothy H Fisher, Clara A. Storvick   +2 more
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Associations of serum vitamin B6 status with the risks of cardiovascular, cancer, and all-cause mortality in the elderly [PDF]

Frontiers in Immunology
BackgroundThere are few studies investigating the relationship between serum vitamin B6 and mortality risk in the elderly. This study hereby evaluated the associations between biomarkers of serum vitamin B6 status and cardiovascular, cancer, and all ...
Pengxi Wang, Pengxi Wang, Jia Huang, Feng Xue, Munire Abuduaini, Yuchang Tao, Hongyan Liu   +6 more
doaj   +2 more sources

The Determination of 4-Pyridoxic Acid in Human Urine

Journal of Biological Chemistry, 1958
Saranya Kumari Reddy, May S. Reynolds, J. M. Price   +2 more
openalex   +3 more sources