Results 11 to 20 of about 28,111 (262)
Angewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022 Benzoxazolinate is a rare bis‐heterocyclic moiety that interacts with proteins and DNA. It was found that a putative acyl AMP‐ligase mediates the last cyclization step to afford benzoxazolinate. The enzyme was then used as a probe for genome mining, which led to the discovery of a new class of benzoxazolinate‐containing compounds in diverse bacteria ...
Yi‐Ming Shi +12 more
wiley +2 more sources
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 234-237, January 2023., 2023 Abstract Adenylosuccinase deficiency is a rare inborn error of metabolism. We present a newborn who died at 52 days of age with clinical features suggestive of severe epileptic encephalopathy and leukodystrophy of unknown cause. Post‐mortem examination showed an unusual vacuolar appearance of the brain.
Spatikha Sitaram +11 more
wiley +1 more source
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Considering the complications related to alcohol withdrawal syndrome (AWS) such as seizure, delirium tremens and cardiac arrhythmia, it is important to identify the risk of delirium tremens (DT) following AWS and enhance preventive strategies. We observed the characteristics of quantitative electroencephalography in patients with AWS, specifically who ...
Jee‐Eun Yoon +3 more
wiley +1 more source
ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022 Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley +1 more source
Pyridoxine‐responsive KCNQ2 epileptic encephalopathy: Additional cases and literature review
Molecular Genetics & Genomic Medicine, 2022 Background Typical patients with KCNQ2 (OMIM# 602235) epileptic encephalopathy present early neonatal‐onset intractable seizures with a burst suppression EEG pattern and severe developmental delay or regression, and those patients always fail first‐line ...
Jun Chen +8 more
doaj +1 more source
USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS
Сибирский онкологический журнал, 2017 We presented results of monotherapy and combination therapy of transplantable murine tumor models using methionine-gamma-lyase (MGL) and pyridoxine hydrochloride. We studied MGL from Clostridium sporogenes and Citrobacter freundii.
D. Zh. Davydov +8 more
doaj +1 more source
Cells, 2020 Pyridoxine, one of the vitamin B6 vitamers, plays a crucial role in amino acid metabolism and synthesis of monoamines as a cofactor. In the present study, we observed the effects of pyridoxine deficiency on novel object recognition memory.
Hyo Young Jung +9 more
doaj +1 more source
Pyridoxine: The ‘Ba.Six’ of use in Nausea and Vomiting of Pregnancy [PDF]
Journal of Clinical and Diagnostic Research, 2019 Over the centuries, the dietary and biochemical essentiality of pyridoxine in the humans has been well established. Apart from various physiological functions, pyridoxine is therapeutically important in Nausea and Vomiting of Pregnancy (NVP).
Abbas Hassan +2 more
doaj +1 more source
Brain Sciences, 2021 Pyridoxine-dependent epilepsy (PDE) is an autosomal recessive neurometabolic disorder due to a deficiency of α-aminoadipic semialdehyde dehydrogenase (mutation in ALDH7A1 gene), more commonly known as antiquitin (ATQ).
Konrad Kaminiów +3 more
doaj +1 more source
Effects of Pyridoxine on Growth Performance and Plasma Aminotransferases and Homocysteine of White Pekin Ducks [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 A dose-response experiment with seven supplemental pyridoxine levels (0, 0.66, 1.32, 1.98, 2.64, 3.30, and 3.96 mg/kg) was conducted to investigate the effects of pyridoxine on growth performance and plasma aminotransferases and homocysteine of White ...
Ming Xie +4 more
doaj +1 more source