Results 11 to 20 of about 70,295 (294)

4-Pyridoxic Acid/Pyridoxine Ratio in Patients with Type 2 Diabetes is Related to Global Cardiovascular Risk Scores

Diagnostics, 2019
Background: Vascular diseases are multifactorial and several risk factors may have synergetic effect on the global vascular risk. Among patients with diabetes, we investigated whether vitamin B6 species differ according to global cardiovascular risk ...
Rima Obeid, Juergen Geisel, Wilfred A. Nix   +2 more
doaj   +2 more sources

8-Way Randomized Controlled Trial of Doxylamine, Pyridoxine and Dicyclomine for Nausea and Vomiting during Pregnancy: Restoration of Unpublished Information. [PDF]

PLoS ONE, 2017
OBJECTIVESWe report information about an unpublished 1970s study ("8-way" Bendectin Study) that aimed to evaluate the relative therapeutic efficacy of doxylamine, pyridoxine, and dicyclomine in the management of nausea and vomiting during pregnancy.
Rujun Zhang, Navindra Persaud
doaj   +2 more sources

POTENTIOMETRIC AND CONDUCTIMETRIC STUDIES OF CHEMICAL EQUILIBRIA FOR PYRIDOXINE HYDROCHLORIDE IN AQUEOUS SOLUTIONS: SIMPLE EXPERIMENTAL DETERMINATION OF PKA VALUES AND ANALYTICAL APPLICATIONS TO PHARMACEUTICAL ANALYSIS

Eclética Química, 2018
The combination of two low-cost classical procedures based on titrimetric techniques is presented for the determination of pyridoxine hydrochloride in pharmaceuticals samples.
Thiago de Almeida Drumond dos Santos, Diego Oliveira da Costa, Samuel Silva da Rocha Pita, Felipe Silva Semaan   +3 more
doaj   +2 more sources

Doxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: Prespecified analyses and reanalysis

PLoS ONE, 2018
Background Doxylamine-pyridoxine is recommended as a first line treatment for nausea and vomiting during pregnancy and it is commonly prescribed. We re-analysed the findings of a previously reported superiority trial of doxylamine-pyridoxine for the ...
Navindra Persaud, Christopher Meaney, Khaled El-Emam, Rahim Moineddin, Kevin E. Thorpe   +4 more
openalex   +3 more sources

SP, CGRP changes in pyridoxine induced neuropathic dogs with nerve growth factor gene therapy [PDF]

BMC Neuroscience, 2016
Nerve growth factor (NGF) is known not only as a major factor for neuronal plasticity but also as a pain stimulator. Although there have been several trials with NGF for its application in the regeneration or protection of the nervous system, the pain ...
Jooyeon Kang, Dae Young Yoo, Kwon-Young Lee, Wooseok Im, Manho Kim, Jung Hoon Choi, Hwa‐Young Youn, Sae Hoon Kim, In Koo Hwang, Jin Young Chung   +9 more
openalex   +2 more sources

Association Between Lysine Reduction Therapies and Cognitive Outcomes in Patients With Pyridoxine-Dependent Epilepsy

Neurology, 2022
Background and Objectives Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is a developmental epileptic encephalopathy characterized by seizure improvement after pyridoxine supplementation.
C. Coughlin, L. Tseng, L. Bok, H. Hartmann, E. Footitt, P. Striano, B. Tabarki, R. Lunsing, S. Stockler-Ipsiroglu, S. Gordon, J. V. Van Hove, J. Abdenur, M. Boyer, N. Longo, A. Andrews, M. Janssen, A. V. van Wegberg, C. Prasad, A. Prasad, M. Lamb, F. Wijburg, S. Gospe, C. V. van Karnebeek   +22 more
semanticscholar   +1 more source

New Derivatives of Pyridoxine Exhibit High Antibacterial Activity against Biofilm-EmbeddedStaphylococcusCells [PDF]

BioMed Research International, 2015
Opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on tissues and inorganic surfaces. In the biofilm bacterial cells are embedded in a self-produced polysaccharide matrix and thereby are inaccessible to ...
Airat R. Kayumov, Aliya A. Nureeva, Elena Y. Trizna, Guzel R. Gazizova, Mikhail I. Bogachev, Nikita V. Shtyrlin, Mikhail V. Pugachev, Sergey V. Sapozhnikov, Yurii G. Shtyrlin   +8 more
openalex   +2 more sources

Impact of vitamin B6 deficiency on the severity of diabetic peripheral neuropathy – A cross sectional study

Saudi Pharmaceutical Journal, 2023
Background: Diabetic Peripheral Neuropathy is one of the most important and significantly prevalent microvascular complications of Diabetes Mellitus. Pyridoxine is a key nutrient for protecting nerve health. The objective of this research is to study the
Moteb Khobrani, Geetha Kandasamy, Rajalakshimi Vasudevan, AbdulAziz Alhossan, Ranadheer Chowdary Puvvada, Praveen Devanandan, Rajeshri Dhurke, Manusri Naredla   +7 more
doaj   +1 more source

Pyridoxine deficiency modulates benzene inhalation-induced hematotoxicity associated with hepatic CYP2E1 activity in B6C3F1 mice

Toxicology Reports, 2021
Pyridoxine is a co-factor in many enzymatic reactions and impacts of deficiency have been observed in affected populations. A possible modifying effect of pyridoxine deficiency on benzene toxicity was assessed in male B6C3F1 mice fed either a pyridoxine ...
Chanthana Tangjarukij, Daam Settachan, Judith T. Zelikoff, Panida Navasumrit, Mathuros Ruchirawat   +4 more
doaj   +1 more source

The Impacts of Graded Doses of Pyridoxine on the Biomarkers, Aspartate Aminotransferase, lactate Dehydrogenase and Total Antioxidant Capacity in Doxorubicin-Induced Cardiotoxicity in Female Rats

Iraqi Journal of Pharmaceutical Sciences, 2017
:        The aim of the current study was to investigate the possible protective effect of graded doses (5, 10, and 15mg/kg) of pyridoxine hydrochloride intraperitoneally injected against (15mg/kg) doxorubicin-induced cardiotoxicity in female rats ...
Doaa Kadhim Abdul Ridha, Nada Naji Al-Shawi   +1 more
doaj   +3 more sources