Results 41 to 50 of about 3,638 (238)

Efeito analgésico de antagonistas do receptor da histamina H1 em modelo de dor provocada por formalina em ratos Efecto analgésico de antagonistas del receptor de la histamina H1 en un modelo de dolor provocado por formalina en ratones Analgesic effects of H1 receptor antagonists in the rat model of formalin-induced pain

Revista Brasileira de Anestesiologia, 2009
JUSTIFICATIVA E OBJETIVOS: Os receptores de histamina mediam vias nociceptivas principalmente no sistema nervoso central. Alguns estudos mostraram efeito analgésico de antagonistas de receptor de histamina no sistema nervoso periférico. Não está claro se
Hazem Adel Ashmawi, Leandro Mamede Braun, Angela Maria Sousa, Irimar de Paula Posso   +3 more
doaj   +1 more source

Unicompartmental knee arthroplasty: A PearlDiver study evaluating complications rates, opioid use and utilization in the Medicare population

Journal of Experimental Orthopaedics, Volume 8, Issue 1, 2021., 2021
Abstract Purpose Despite increased utilization of unicompartmental knee arthroplasty (UKA) for unicompartmental knee osteoarthritis, outcomes in Medicare patients are not well‐reported. The purpose of this study is to analyze practice patterns and outcome differences between UKA and TKA in the Medicare population.
Brandon L. Morris, Jack M. Ayres, Daniel Reinhardt, Armin Tarakemeh, Scott Mullen, J. Paul Schroeppel, Bryan G. Vopat   +6 more
wiley   +1 more source

Cytokine responses of intraepithelial lymphocytes are regulated by histamine H2 receptor [PDF]

, 2009
Backgrounds. Histamine participates in the immune regulation of several gastrointestinal diseases. However, the effect of histamine on intestinal intraepithelial lymphocytes (IELs), the front line of intestinal mucosal immune system, is not well ...
A Di Sabatino, A Hayday, A Mazzoni, Akira Hishida, B Lagier, C Lundqvist, CA Akdis, CA Akdis, CC Fox, D Montufar-Solis, E Bolton, E Masini, G Barbara, G Caron, G Monteleone, H Cheroutre, H Cheroutre, H Kiyono, HD Lim, HK Takahashi, IJ Elenkov, K Hoshino, K Takahashi, K Tomita, Kosuke Takagaki, L Knutson, L Lefrancois, LB Hough, LB Svendsen, LE Sander, M Jutel, M Kawaguchi, M Watanabe, Mutsuhiro Ikuma, N Osna, N Osna, P Parronchi, R Boismenu, R Leurs, RL Mosley, S Bischoff, S Kapoor, S Matsumoto, S Takamatsu, S Winterkamp, Satoshi Osawa, T Morichika, T Taguchi, T Taguchi, TA Barrett, Takahisa Furuta, Takanori Yamada, WJ Adams, WJ Adams, Y Horio, Y Sonobe, Yasuhiro Takayanagi, Yasushi Hamaya, Yoshiaki Horio   +58 more
core   +4 more sources

Carrier-Mediated Delivery of Low-Molecular-Weight N-Containing Drugs across the Blood–Brain Barrier or the Blood–Retinal Barrier Using the Proton-Coupled Organic Cation Antiporter

Future Pharmacology, 2023
While it is true that pharmacotherapy has achieved desired health outcomes, significant unmet medical needs persist in the field of central nervous system (CNS) drugs, particularly for neurodegenerative diseases such as Alzheimer’s disease, as well as ...
Toshihiko Tashima
doaj   +1 more source

Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation. [PDF]

PLoS ONE, 2014
The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing,
Liliana Purón-Sierra, María Isabel Miranda   +1 more
doaj   +1 more source

Histamine inhibits adrenocortical cell proliferation but does not affect steroidogenesis. [PDF]

, 2014
Histamine (HA) is a neurotransmitter synthesized in most mammalian tissues exclusively by histidine decarboxylase enzyme. Among the plethora of actions mediated by HA, the modulatory effects on steroidogenesis and proliferation in Leydig cells (LCs) have
Mondillo, Carolina, Monzón, Casandra Margarita, Pagotto, Romina María del Luján, Pereyra, Elba Nora, Pignataro, Omar Pedro   +4 more
core   +2 more sources

Prokinetic and laxative effects of the crude methanolic extract of Viola betonicifolia whole plant in rodents [PDF]

, 2013
Background: The present study was aimed to provide ethnopharmacological basis for the medicinal use of Viola betonicifolia whole plant in indigestion and constipation.
Gilani, Anwar, Khan, Haroon, Muhammad, Naveed, Rehman,, Najeeb, Saeed, Muhammad   +4 more
core   +2 more sources

Uptake Study in Lysosome-Enriched Fraction: Critical Involvement of Lysosomal Trapping in Quinacrine Uptake but Not Fluorescence-Labeled Verapamil Transport at Blood-Retinal Barrier

Pharmaceutics, 2020
Lysosomal trapping at the blood–retinal barrier (BRB) was investigated through quinacrine and fluorescence-labeled verapamil (EFV) uptake. Quinacrine uptake by conditionally immortalized rat retinal capillary endothelial (TR-iBRB2) cells suggested ...
Yoshiyuki Kubo, Miki Yamada, Saki Konakawa, Shin-ichi Akanuma, Ken-ichi Hosoya   +4 more
doaj   +1 more source

Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS. [PDF]

, 2017
Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis.
Aguilera-Lizarraga, J, Balemans, D, Boeckxstaens, GE, Bulmer, DC, Cibert-Goton, V, Dooley, J, Liston, A, Mondelaers, SU, Stakenborg, N, Vanden Berghe, P, Wouters, MM   +10 more
core   +2 more sources

Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II

E-Journal of Chemistry, 2010
Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug ...
V. Annapurna, G. Jyothi, T. Rohini Kumari, B. B. V. Sailaja   +3 more
doaj   +1 more source