Results 41 to 50 of about 3,728 (241)
Frontiers in Psychiatry, 2012 Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics.
Kjell A Svensson
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Future Pharmacology, 2023 While it is true that pharmacotherapy has achieved desired health outcomes, significant unmet medical needs persist in the field of central nervous system (CNS) drugs, particularly for neurodegenerative diseases such as Alzheimer’s disease, as well as ...
Toshihiko Tashima
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Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation. [PDF]
PLoS ONE, 2014 The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing,
Liliana Purón-Sierra +1 more
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Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II
E-Journal of Chemistry, 2010 Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug ...
V. Annapurna +3 more
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Fluids and Barriers of the CNS, 2013 Background Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs.
Shimomura Keita +6 more
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Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS. [PDF]
, 2017 Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis.
Aguilera-Lizarraga, J +10 more
core +2 more sources
Rodent models of complement activation-related pseudoallergy: Inducers, symptoms, inhibitors and reaction mechanisms [PDF]
, 2015 Complement activation-related pseudoallergy (CARPA) is a hypersensitivity reaction to intravenous administration of nanoparticle-containing medicines (nanomedicines).
Dézsi, László +4 more
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Mexican Journal of Medical Research ICSA, 2013 Dysmenorrhea is one of the cyclical processes in chronic pelvic pain. Dysmenorrhea in women causes a high psychosocial and economic impact. For this reason, we conducted a study to assess the prevalence, impact and use of drugs for the treatment of ...
Héctor A. Ponce-Monter +8 more
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A Simple Method for Determination of Chloropyramine in Tablets [PDF]
, 2015 A simple gas chromatography method with mass detection (GC-MS) for the determination of chloropyramine active pharmaceutical ingredient (API) in tablets was developed.
Andersson, Gerhard +3 more
core +6 more sources
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery [PDF]
FASEB JDeveloping an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Khosrowshahi D, Lagae L, Bolander J.
europepmc +2 more sources