Results 51 to 60 of about 2,422 (193)
Inonotus obliquus attenuates histamine-induced microvascular inflammation.
Cell-to-cell communication is a key element of microvascular blood flow control, including rapidly carrying signals through the vascular endothelium in response to local stimuli.
Sumreen Javed +8 more
doaj +1 more source
Proanthocyanidins are condensed tannins present in fruits, vegetables, and flowers, consumed in the human diet. These compounds are believed to decrease coronary heart disease.
Silvia DalBó +6 more
doaj +1 more source
Indometh acin-antihistamine combination for gastric ulceration control [PDF]
An anti-inflammatory and analgesic composition containing indomethacin and an H2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin was developed.
Brown, P. A., Vernikos, J.
core +1 more source
Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep [PDF]
Pharmacological studies in mammals and zebrafish suggest that histamine plays an important role in promoting arousal. However, genetic studies using rodents with disrupted histamine synthesis or signaling have revealed only subtle or no sleep/wake ...
Chen, Audrey +3 more
core +1 more source
The role of GABA-B in sensorigating processing disorders in rat models, an autoradiographic study [PDF]
INTRODUCTION: The process of sensorimotor gating is a neurological phenomenon referring to the brain’s ability to process and filter out stimuli in order to prevent an overflow of information.
Zhuang, Alex
core
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery
Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi +2 more
wiley +1 more source
Background The efficiency and quality of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are crucial for regenerative medicine, disease modeling, drug screening, and the study of the development events during cardiac specification.
Xiaowei Zhu +9 more
doaj +1 more source
Endometriotic cell‐derived HBD‐2 mediated the secretion of histamine from mast cells by binding to MRGPRX2. Histamine sensitized TRPV1 via the activation of HRH1 in pain sensory neurons, thus aggravating hyperalgesia in an endometriosis model. ABSTRACT The studies on how mast cells mediate endometriosis pain are still limited.
Xinqi Mao +6 more
wiley +1 more source
Objective: The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast +2 more
doaj +2 more sources
Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway
Despite pharmacotherapeutic advances, cardiovascular disease (CVD) remains the primary cause of global mortality. Alternative approaches, such as herbal medicine, continue to be sought to reduce this burden.
Adnan Badran +7 more
doaj +1 more source

