Pyrimidine biosynthesis is not an essential function for trypanosoma brucei bloodstream forms [PDF]
, 2013 <p>Background: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.</p> <p>Methodology/Principal ...
A Hofer +51 more
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Synthesis of Pyrimidines and Condensed Pyrimidines [PDF]
Bulletin of the Chemical Society of Japan, 1973 Abstract A new one-step synthesis of pyrimidines and condensed pyrimidines by heating carboxamides or cyclic lactams with formamide in the presence of POCl3 in a sealed tube is described.
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Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy [PDF]
, 2017 Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Ali, Juma A.M. +7 more
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Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]
, 1975 Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Inaba, Kozo, Oda, Takuzo
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13C n.m.r. investigation on the nitrogen methylation of some azabenzenes [PDF]
, 1977 The 1H and 13C n.m.r. spectra of N-methylated pyridine, pyridazine, pyrimidine and pyrazine and N,N-dimethylated pyrimidine and pyrazine have been recorded and analysed.
Mohan, Chandra, Weijer, Peter van de
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PURINE AND PYRIMIDINE ANTAGONISM IN A PYRIMIDINE-DEFICIENT MUTANT OF NEUROSPORA [PDF]
Journal of Biological Chemistry, 1948 The present study is concerned with the inhibition of growth of the pyrimidine-deficient Neurospora mutant, No. 1298, by the naturally occurring purine ribonucleotides and ribonucleosides. This experimentally produced strain, unlike the wild type, is unable to synthesize the pyrimidine ribonucleosides on a medium containing inorganic salts ...
Pierce, John G., Loring, Hubert S.
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Interactions of slow electrons with biomolecules [PDF]
, 2007 We report on results of computational studies of the interaction of slow electrons with the purine and pyrimidine bases of DNA, as well as with their associated nucleosides and nucleotides.
McKoy, Vincent, Winstead, Carl
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SPIRO-PYRIMIDINES. II. CYCLOHEXANE-1,5-SPIRO-PYRIMIDINES. [PDF]
Journal of the American Chemical Society, 1921 n ...
Dox, Arthur W., Yoder, Lester
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N—H⋯N hydrogen bonding in 4,6-diphenyl-2-pyrimidinylamine isolated from the plant Justicia secunda (Acanthaceae) [PDF]
, 2004 The title compound, C₁₆H₁₃N₃, isolated from Justicia secunda (Acanthaceae), comprises two molecules (which differ slightly in conformation) in the asymmetric unit of space group P\overline 1.
Chatterjee, Baidyanath +4 more
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Pyrimidine-2-carboxamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2007 In the crystal strucuture of the title compound, C(5)H(5)N(3)O, which was obtained upon recrystallization of 2-cyano-pyrimidine from aqueous sodium hydroxide, the amide group is twisted with respect to the aromatic ring by 24.9 (1)°. π-π stacking is observed between partially overlapped rings at a face-to-face separation of 3.439 (6) Å.
Jing-Jing Nie, Qian Yang, Bing-Yu Zhang
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