Results 91 to 100 of about 314,968 (285)

Blocked dihydropteridines as nitric oxide synthase activators [PDF]

open access: yes, 2010
It has been shown that 6-acetyl-7,7-dimethyl-5,6,7,8-tetrahydropteridin-4(3H)-one can act as a competent cofactor for the production of nitric oxide by neuronal nitric oxide synthase (nNOS).
Daff, Simon   +5 more
core  

DES‐Promoted Synthesis of 3,4‐Dihydropyrimidinones and Their Antidiabetic and Antioxidant Evaluation Supported With Computational Studies

open access: yesChemistry &Biodiversity, EarlyView.
DES‐promoted synthesis and antidiabetic evaluation of 3,4‐dihydropyrimidinones and their complementation with computational studies are reported. ABSTRACT A series of 3,4‐dihydropyrimidinone (DHPM) derivatives was synthesized using a green deep eutectic solvent (DES) system composed of ZnCl2 and urea, which acted simultaneously as solvent, catalyst ...
Gobind Kumar   +10 more
wiley   +1 more source

Recent progress of pyrimidine derivatives for high-performance organic light-emitting devices

open access: yes, 2018
. Pyrimidine is an electron-deficient azaaromatic compound containing two nitrogen atoms at 1, 3-positions that plays a key role as an organic semiconductor or semiconducting material. Because of the high electron-accepting property induced by C═N double
Ryutaro Komatsu   +2 more
semanticscholar   +1 more source

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

open access: yesChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source

Photoreactivation of Lethal Damage Induced in Hamster X Xenopus Hybrid Cells and Their Parentals by UV Light [PDF]

open access: yes, 1987
A85 Xenopus cells that exhibited a high level of photoreactivation (PR) and V79B2 hamster cells that exhibited little PR were fused to produce the V79B2 x A85 cell line — a hybrid line which possessed a relatively stable karyotype, with most cells ...
Bohlender, David   +3 more
core   +2 more sources

Gankyrin‐Protein Interactions in GI Cancers: A Novel Target of New Therapeutics

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Gankyrin (PSMD10) is a 25 kDa oncogenic protein and regulatory subunit of the 26S proteasome, characterized by a sevenfold ankyrin repeat domain. Gankyrin is overexpressed in various malignancies, particularly gastrointestinal (GI) cancers. Gankyrin contributes to tumorigenesis by modulating key signaling pathways and engaging in oncogenic ...
Shuang Li   +4 more
wiley   +1 more source

Unlocking Biomolecule Modification with Light‐Promoted Photocatalyst‐Free Approaches: Current Tools, Challenges, and Perspectives

open access: yesChemistryEurope, EarlyView.
This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink   +3 more
wiley   +1 more source

Pyrimidine-based twisted donor–acceptor delayed fluorescence molecules: a new universal platform for highly efficient blue electroluminescence

open access: yesChemical Science, 2016
High-efficiency deep blue thermally activated delayed fluorescence (TADF) emitters consisting of acridan–pyrimidine donor–acceptor motifs are developed.
In Seob Park   +2 more
semanticscholar   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

open access: yesChemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

A Growth model for DNA evolution

open access: yes, 1996
A simple growth model for DNA evolution is introduced which is analytically solvable and reproduces the observed statistical behavior of real sequences.Comment: To be published in Europhysics ...
Herrmann, H. J., Vieira, M. de Sousa
core   +1 more source

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