Results 91 to 100 of about 161,675 (297)
In this study, novel pyrazole, imidazole, pyrimidine derivatives bearing imidazo[4,5-b]indol moiety were successfully synthesized and their chemical structures were identified and confirmed by different spectral techniques.
Nadia Ali Ahmed Elkanzi +2 more
doaj +1 more source
A new class of multinucleate pyrimidine chalcogen (Se/Te) derivatives, i.e. 2,4-bis(arylchalcogenyl)pyrimidine and 2-chloro-4,6-bis(arylchalcogenyl)pyrimidine compounds, has been synthesized for the first time by the nucleophilic substitution of chlorine
Mehta, S. K. +7 more
core +1 more source
The evolution of pyrimidine bases
Evolution occurs when genes in a population of cells change in sequence and frequency over time and dominate by modification. However, in the evolutionary process, before the formation of cells, there must also be compounds that form these cells.
Kebabci, Özgür, Tüzün, Burak
core +1 more source
Um außergewöhnlich wirksame Wirkstoffe zu entwickeln, ist es erforderlich, über die Bindungsstelle hinaus zu denken. Diese Arbeit zeigt, dass die auf den ersten Blick kontraintuitive Adressierung einer konservierten Region der Kinase zu einer hochselektiven Bindung führen kann.
Nico J. Seidler +20 more
wiley +1 more source
DNA Backbone Conformation in Cis-Syn Pyrimidine[ ]Pyrimidine Cyclobutane Dimers [PDF]
A theoretical calculation involving minimization of energy functions was made to determine the conformation of a deoxydinucleoside monophosphate pyrimidine[ ]pyrimidine cis-syn cyclobutane dimer. Such single-stranded moieties are useful models for the in
Broyde, Suse B. +2 more
core +1 more source
Aim. To study profoundly the antimicrobial activity of the derivatives of 6-(1,2,4-oxadizol-3-yl)- and 6-(2-aminothiazol-4-yl)thieno[2,3-d]pyrimidin-4-ones by the double dilution method. Results and discussion. For the derivatives of 6-heterylthieno[2,3-
Sergiy V. Vlasov +3 more
doaj +1 more source
International audienceAbstract An efficient and original synthesis of various 2,4,7‐trisubstituted pyrido[3,2‐ d ]pyrimidines is reported. The first access to and the chemical interest of 2,4,7‐trichloropyrido[3,2‐ d ]pyrimidine is described.
Massip, Stéphane +13 more
core +1 more source
4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof [PDF]
The present invention relates to a compound 4-substituted derivative of pyrazolo[3,4-d]pyrimidine or of pyrrolo[2,3-d]pyrimidine having the formula (I) and uses thereof, in particular for the treatment of bone related diseases and ...
Bruno Olga +13 more
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