Results 91 to 100 of about 161,675 (297)

Synthesis and Antimicrobial Evaluation of Novel Pyrazole, Imidazole and Pyrimidine Derivatives Possessing Imidazo[4,5-b]indol Moiety

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
In this study, novel pyrazole, imidazole, pyrimidine derivatives bearing imidazo[4,5-b]indol moiety were successfully synthesized and their chemical structures were identified and confirmed by different spectral techniques.
Nadia Ali Ahmed Elkanzi   +2 more
doaj   +1 more source

Synthesis of new organochalcogen (Se or Te) based multifunctional pyrimidine derivatives: X-ray structure determination of 2,4-bis (arylchalcogenyl)pyrimidine and 2-chloro-4,6-bis(arylchalcogenyl) pyrimidine compounds

open access: yes
A new class of multinucleate pyrimidine chalcogen (Se/Te) derivatives, i.e. 2,4-bis(arylchalcogenyl)pyrimidine and 2-chloro-4,6-bis(arylchalcogenyl)pyrimidine compounds, has been synthesized for the first time by the nucleophilic substitution of chlorine
Mehta, S. K.   +7 more
core   +1 more source

pyrimidine metabolism-png

open access: yes, 2014
unigenes related to pyrimidine ...
Karen Fugate (480954)
core   +1 more source

The evolution of pyrimidine bases

open access: yes
Evolution occurs when genes in a population of cells change in sequence and frequency over time and dominate by modification. However, in the evolutionary process, before the formation of cells, there must also be compounds that form these cells.
Kebabci, Özgür, Tüzün, Burak
core   +1 more source

Über die Bindungsstelle hinausgedacht: Ein sich selbsteinkapselnder Kinase‐Inhibitor modelliert seine Bindetasche und erzielt so Selektivität

open access: yesAngewandte Chemie, EarlyView.
Um außergewöhnlich wirksame Wirkstoffe zu entwickeln, ist es erforderlich, über die Bindungsstelle hinaus zu denken. Diese Arbeit zeigt, dass die auf den ersten Blick kontraintuitive Adressierung einer konservierten Region der Kinase zu einer hochselektiven Bindung führen kann.
Nico J. Seidler   +20 more
wiley   +1 more source

pyrimidine metabolism-html

open access: yes, 2014
unigenes related to pyrimidine ...
Karen Fugate (480954)
core   +1 more source

DNA Backbone Conformation in Cis-Syn Pyrimidine[ ]Pyrimidine Cyclobutane Dimers [PDF]

open access: yes, 1980
A theoretical calculation involving minimization of energy functions was made to determine the conformation of a deoxydinucleoside monophosphate pyrimidine[ ]pyrimidine cis-syn cyclobutane dimer. Such single-stranded moieties are useful models for the in
Broyde, Suse B.   +2 more
core   +1 more source

The study of the antimicrobial activity of the derivatives of 6-(1,2,4-oxadizol-3-yl)- and 6-(2-aminothiazol-4-yl)thieno[2,3-d]pyrimidin-4-ones by the double dilution method

open access: yesЖурнал органічної та фармацевтичної хімії, 2019
Aim. To study profoundly the antimicrobial activity of the derivatives of 6-(1,2,4-oxadizol-3-yl)- and 6-(2-aminothiazol-4-yl)thieno[2,3-d]pyrimidin-4-ones by the double dilution method. Results and discussion. For the derivatives of 6-heterylthieno[2,3-
Sergiy V. Vlasov   +3 more
doaj   +1 more source

]pyrimidine

open access: yes, 2012
International audienceAbstract An efficient and original synthesis of various 2,4,7‐trisubstituted pyrido[3,2‐ d ]pyrimidines is reported. The first access to and the chemical interest of 2,4,7‐trichloropyrido[3,2‐ d ]pyrimidine is described.
Massip, Stéphane   +13 more
core   +1 more source

4-Substituted derivatives of pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine and uses thereof [PDF]

open access: yes, 2013
The present invention relates to a compound 4-substituted derivative of pyrazolo[3,4-d]pyrimidine or of pyrrolo[2,3-d]pyrimidine having the formula (I) and uses thereof, in particular for the treatment of bone related diseases and ...
Bruno Olga   +13 more
core  

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