Substituent-controlled visible light photoisomerization and cyclodimerization of styryl pyrimidinones. [PDF]
Polynski MV +4 more
europepmc +1 more source
Zero‐dimensional organic–inorganic hybrid materials (Cyt)2ZnX4·H2O (X = Cl, Br) were synthesized using cytosine (Cyt) and zinc halides, enabling effective regulation of room‐temperature phosphorescence (RTP) through halogen substitution in the inorganic [ZnX4]2− unit.
Chenxin Fan +6 more
wiley +1 more source
Purine and pyrimidine analogs differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin-resistant <i>Staphylococcus aureus</i>. [PDF]
Nolan AC, Byrne S, Zeden MS, O'Gara JP.
europepmc +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Effects of Combined Aerobic and Resistance Exercise on Liver Metabolomics in Mice Fed a High-Fat Diet. [PDF]
Wang Y, Gao P, Hao Z, Wu L.
europepmc +1 more source
Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri +2 more
wiley +1 more source
UV mutagenesis of Streptomyces sp. KRA0514‐6 yielded HL‐3, a novel streptothricin‐like compound (C17H29N7O8) with N‐methylglycine replacing β‐lysine, achieving 100% cabbage soft rot control at >1 ppm concentration. Abstract BACKGROUND A total of 1000 soil‐derived actinomycetes were isolated and screened for antibacterial activity against Pectobacterium
Young Sook Kim +5 more
wiley +1 more source
Application of aiAtlas Version 1.2 to Simulate Variant Gene Function Restoration and Rescue Thresholds in Rare Diseases: Validation Case Study. [PDF]
Danter W.
europepmc +1 more source
Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano +7 more
wiley +1 more source
HSV-1 UL42 and UL47 hijack cellular nucleotide synthetic enzyme CAD to promote lytic replication. [PDF]
Qin C +5 more
europepmc +1 more source

