The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Japanese encephalitis virus reprograms host pyrimidine metabolism to facilitate viral replication. [PDF]
Gu J +6 more
europepmc +1 more source
Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence. [PDF]
Joshi R, McEwan AG, Kappler U.
europepmc +1 more source
Oxaziridines: Versatile Reagents in Modern Organic Synthesis
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra +2 more
wiley +1 more source
Recent Advances in Pyrimidine Molecular Hybrids, Green Synthetic Strategies, and Diverse Biological Applications. [PDF]
Belete M, Melaku Y, Mulugeta E.
europepmc +1 more source
Spatial Gene Expression in Fungi: mRNA Localization, Condensates, and Beyond
ABSTRACT Polarized growth and cellular asymmetry are broadly conserved properties of fungal life, from transient bud‐site selection in unicellular yeasts to sustained hyphal extension in filamentous and coenocytic species. While vesicle trafficking, cytoskeletal organization, and cell‐wall remodeling are well‐established contributors to these processes,
Sander van Otterdijk +3 more
wiley +1 more source
Thieno[3,2-<i>d</i>]pyrimidines in Anticancer Drug Discovery: Recent Advances in Drug Design and Molecular Targets. [PDF]
Buronov A +22 more
europepmc +1 more source
Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff +4 more
wiley +1 more source
Tunable Sulfenylnitrenes Enable Scaffold Hopping of Furans Into N-Heterocycles. [PDF]
Kafle P +8 more
europepmc +1 more source

