Results 141 to 150 of about 161,675 (297)

Thermal Nickel‐Catalyzed N‐Arylation of Sulfonimidamides With (Hetero)aryl Chlorides Enabled by PAd‐DalPhos Ligation

European Journal of Organic Chemistry, EarlyView.
The nickel‐catalyzed S═NH N‐arylation of sulfonimidamides is described, with useful demonstrated substrate scope involving inexpensive and widely available (hetero)aryl chloride reaction partners, including the active pharmaceutical ingredient chlorpromazine.
Samuel A. Fisher, Patrick L. DeRoy, Mark Stradiotto   +2 more
wiley   +1 more source

Pyrimidine- and furo[2,3-<i>d</i>]pyrimidine-isoxazole hybrids and their Re(i) tricarbonyl complexes with antiproliferative activity against hematological malignancies. [PDF]

RSC Med Chem
Piškor Benković M, Ćorić I, Sačer L, Damjanović L, Mišković Špoljarić K, Perić B, Kirin SI, Glavaš-Obrovac L, Raić-Malić S.   +8 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Quinazoline-tethered thiazolo[3,2-<i>a</i>]pyrimidines and their cyclic chalcone derivatives as HIV-1 reverse transcriptase inhibitors: green synthesis, molecular docking, and <i>in silico</i> studies. [PDF]

RSC Adv
Gomha SM, Al-Hussain SA, Sulaiman YAM, Riyadh SM, Farag B, Alhilal M, Alhilal S, Zaki MEA.   +7 more
europepmc   +1 more source

Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes

FlexMat, EarlyView.
Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi, Shuyuan Ge, Futong Liu, Ping Lu   +3 more
wiley   +1 more source

Pyridine‐dicarbonitriles acceptor engineering in multi‐resonance thermally activated delayed fluorescence with hybridized short‐ and long‐range charge transfer for high‐performance electroluminescence

FlexMat, EarlyView.
Pyridine‐dicarbonitrile units integrated into a multiple‐resonance core engineer the excited state through cooperative short‐range charge transfer (SRCT) and long‐range charge transfer (LRCT), thereby enhancing the spin‐flipping process. Abstract Multi‐resonance (MR) thermally activated delayed fluorescence (TADF) materials exhibit narrowband emission ...
Jing Sun, Zezhu Xiao, Wei Li, Songqian Ni, Haorun Dai, Xiangyun Wang, Jiasen Zhang, Weiguo Zhu, Ziyi Ge, Xiugang Wu   +9 more
wiley   +1 more source

Host-pathogen pyrimidine metabolism drives cystic fibrosis lung disease. [PDF]

Nat Commun
Lohia GK, Chen YT, Chen S, Beg A, Theiller E, Cui A, Moustafa AM, Riquelme SA.   +7 more
europepmc   +1 more source

RESEARCHES ON PYRIMIDINES: PYRIMIDINE-NUCLEOSIDES

Journal of Biological Chemistry, 1913
Treat B. Johnson, Lewis H. Chernoff
openaire   +1 more source

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

iMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang, Fei Pan, Yachun Li, Yimeng Wang, Ze Wang, Zhiheng Huang, Ming Chen, Yun Li, Mengli Huang, Cheng Guo, Chubo Xie, Lina Dong, Yadong Gao, Zhuohang Yu   +13 more
wiley   +1 more source

Gut microbiome seasonality is associated with dietary plasticity and coexistence in three sympatric Pamir ungulates

iMetaOmics, EarlyView.
This graphical abstract outlines a multi‐omics framework investigating the seasonal dietary composition and gut microbial communities of three coexisting ungulate species inhabiting the extreme high‐altitude Pamir Plateau (Ovis ammon polii, Capra sibirica, and Pseudois nayaur). By integrating dietary DNA metabarcoding, 16S rRNA gene sequencing, shotgun
Dilala Tuoliu, Lijiao Zhang, Muyang Wang, Wenxuan Xu, Kathreen Ruckstuhl, António Alves da Silva, Joana Alves, Hongchen Jiang, Weikang Yang   +8 more
wiley   +1 more source