Design, synthesis, <i>in silico</i> studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine. [PDF]
Ataollahi E+9 more
europepmc +1 more source
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis
A key organismal response to overnutrition involves the development of new adipocytes through the process of adipogenesis. Preadipocytes sense changes in the systemic nutrient status and metabolites can directly modulate adipogenesis.
Julia A. Pinette+16 more
doaj
THE INCORPORATION OF THE PYRIMIDINE RING OF ADENINE INTO THE ISOALLOXAZINE RING OF RIBOFLAVIN
Walter S. McNutt
openalex +1 more source
Catalytic application of a bimetallic-organic framework with phosphorus acid groups in the preparation of pyrido[2,3-<i>d</i>]pyrimidines <i>via</i> cooperative vinylogous anomeric-based oxidation. [PDF]
Ataee-Najari AR+5 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Oxazolo[5,4-d]pyrimidines as Anticancer Agents: A Comprehensive Review of the Literature Focusing on SAR Analysis. [PDF]
Sochacka-Ćwikła A, Mączyński M.
europepmc +1 more source
THE PURINE AND PYRIMIDINE COMPOSITION OF THE TOBACCO MOSAIC VIRUS AND THE HOLMES MASKED STRAIN
William D. Cooper, Hubert S. Loring
openalex +1 more source
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang+15 more
wiley +1 more source
Our study observed a plausible association between CRF and gut microbiota composition, with increasing proinflammation taxa in severe CRF patients and anti‐inflammation taxa growing in mild CRF patients. Abstract Background Cancer survivors perceive cancer‐related fatigue (CRF) as one of the most common symptoms.
Hao Wei+6 more
wiley +1 more source