Results 181 to 190 of about 197,991 (343)

Uncovering the Role of DNA Repair Impairment in UVA‐Induced Mutagenesis in Human Xeroderma Pigmentosum Variant Cells

Molecular Carcinogenesis, EarlyView.
ABSTRACT Ultraviolet A (UVA) radiation induces DNA damage both directly, by forming cyclobutane pyrimidine dimers (CPDs), and indirectly, by generating oxidative stress. Cells rely on nucleotide excision repair (NER) and translesion synthesis (TLS) to tolerate these lesions.
Camila Corradi, Natália Cestari Moreno, Nathalia Quintero‐Ruiz, Giovana da Silva Leandro, Marcela Teatin Latancia, Tiago Antonio de Souza, Veridiana Munford, Carlos Frederico Martins Menck   +7 more
wiley   +1 more source

One-Pot Synthesis of Novel Pyrimidine Derivatives with Potential Antidiabetic Activity Through Dual α-Glucosidase and α-Amylase Inhibitors. [PDF]

Molecules
Al-Shehri O, Abubshait S, Nawaz M, Gomaa MS, Abubshait HA.   +4 more
europepmc   +1 more source

Inability of two Hydantoins to act as Precursors of Pyrimidines in Ribonucleic Acid. [PDF]

, 1950
S. Bergström, E. Hammarsten, Peter Reichard   +2 more
openalex   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

Skeletal editing of 4-arylpyrimidines into diverse nitrogen heteroaromatics via four-atom synthons. [PDF]

Nat Commun
Li S, Shi Y, Tang J, Yan M, Huang S, Dou T, Wang S, Jin X, Su Z, Jiang W, Xu J, Zheng X, Li R, Chen H, Xue W, Fu H.   +15 more
europepmc   +1 more source

Studies on Pyrimidine Derivatives. I

, 1958
Kenzo Sirakawa
openalex   +2 more sources

A Comprehensive Review of Magnetic Nanocatalysts for C−S, C−Se Bond Formation

ChemistryOpen, EarlyView.
This review manuscript provides an exhaustive examination of magnetic nanocatalysts and their pivotal role in the formation of carbon‐sulfur (C−S) and carbon‐selenium (C−Se) bonds. The study delves into the latest advancements in the synthesis, characterization, and application of magnetic nanocatalysts, highlighting their unique advantages, including ...
Radwan Ali, Jianlin Han, Mosstafa Kazemi, Ramin Javahershenas   +3 more
wiley   +1 more source

Syntheses of Pyrimidine Compounds. IV

, 1949
Taizo Matsukawa, Buhachiro Ohta
openalex   +2 more sources

Evaluation of the Antifungal Properties of Azomethine‐Pyrazole Derivatives from a Structural Perspective

ChemistryOpen, EarlyView.
A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo, Andrés Camilo Restrepo‐Acevedo, Cristian Rocha‐Roa, Susana Zacchino, Laura Svetaz, Simón Hernández‐Ortega, Rodrigo Abonia, Ronan Le Lagadec, Fernando Cuenú‐Cabezas   +8 more
wiley   +1 more source

Preparation and characterization of kaolin-[TMS]-NH₂ ⁺C(NO₂)₃ ^- as a novel heterogeneous nano-catalyst and its use in the synthesis of imidazo[1,2-<i>a</i>]pyrimidine and 1,2,4-triazolo[4,3-<i>a</i>]pyrimidines. [PDF]

RSC Adv
Dorostkar M, Nazemi-Nasyrmahale L, Shirini F.   +2 more
europepmc   +1 more source