Results 211 to 220 of about 282,247 (397)

A Robust Strategy for Introducing Amino‐Modifiers in Nucleic Acids: Enabling Novel Amino Tandem Oligonucleotide Synthesis in DNA and RNA

open access: yesChemistry – A European Journal, EarlyView.
We report a simple, efficient, and cost‐effective methodology for introducing amino‐modifiers into DNA and RNA using a commercially available solid support. By incorporating a base‐labile sulfonyl linker within the strand, we developed an amino‐containing tandem oligonucleotide synthesis (aTOS) methodology, which enables the introduction of multiple ...
Jagandeep S. Saraya   +3 more
wiley   +1 more source

Molecular Rectangles Featuring Two Parallel NCN‐Coordinated Platinum Units: Enhancing Near‐Infrared Emission Through Excimer Formation

open access: yesChemistry – A European Journal, EarlyView.
Macro‐cycling into the near‐infrared: By incorporating two cyclometallated Pt(II) units into opposite sides of a molecular rectangle, the formation of near‐infrared‐emitting excited states that span the two units is promoted in solution, compared to the corresponding, acyclic, tweezer‐like complexes. A degree of molecular reorganization is nevertheless
Rebecca J. Salthouse   +4 more
wiley   +1 more source

Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate and Imidazole Functional Groups in the Major Groove

open access: yesChemistry – A European Journal, Accepted Article.
We designed and synthesized a set of six 2’‐deoxyribonucleoside 5’‐O‐triphosphates (dNTPs) bearing functional groups mimicking amino acid side chains in enzyme active sites (OH, SH, COOH and imidazole) attached to position 5 of pyrimidines or position 7 of 7‐deazapurines through different linkers.
Lukáš Kaiser   +4 more
wiley   +1 more source

Light‐Responsive Mononucleotide Coacervates

open access: yesChemistry – A European Journal, EarlyView.
Light‐responsive mononucleotide coacervates undergo reversible phase transitions via azobenzene photoisomerization. Coacervates with high‐valency azobenzenes remain stable under UV light, while those with low‐valency azobenzenes dissolve, enabling nucleotide release. This minimal system highlights the potential role of light for exploring energy‐driven
Edison Rafael Jimenez Granda   +4 more
wiley   +1 more source

Investigations into the characterization, degradation, and applications of biodegradable polymers by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli   +2 more
wiley   +1 more source

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