Results 211 to 220 of about 314,968 (285)

Synthesis, <i>in silico</i> and <i>in vitro</i> studies of aminopyrimidine hybrids as EGFR TK inhibitors and anti-proliferative agents. [PDF]

RSC Adv
Shehta W, Farag B, Youssif S, El-Kalyoubi S, Elfeky SM.   +4 more
europepmc   +1 more source

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

Oxidatively Generated Lesions as Internal Photosensitizers for Pyrimidine Dimerization in DNA

, 2018
Isabel Aparici‐Espert, Guillermo García‐Laínez, Inmaculada Andreu, Miguel A. Miranda, Virginie Lhiaubet‐Vallet   +4 more
openalex   +2 more sources

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

Switchable pathways of multicomponent heterocyclizations of 5-amino-1,2,4-triazoles with salicylaldehydes and pyruvic acid. [PDF]

Beilstein J Org Chem
Sakhno YI, Buravov OV, Yurkov KY, Andryushchenko AY, Shishkina SV, Chebanov VA.   +5 more
europepmc   +1 more source

Intramolecular Inverse Electron-Demand [4 + 2] Cycloadditions of Ynamides with Pyrimidines: Scope and Density Functional Theory Insights

, 2017
Guillaume Duret, Robert Quinlan, Boyang Yin, Rainer E. Martin, Philippe Bisseret, Markus Neuburger, Vincent Gandon, Nicolas Blanchard   +7 more
openalex   +1 more source

Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers

Journal of Clinical Investigation, 2017
A. Okazaki, P. Gameiro, Danos C. Christodoulou, Laura Laviollette, Meike Schneider, Frances Chaves, A. Stemmer-Rachamimov, Stephanie A. Yazinski, Richard Lee, G. Stephanopoulos, L. Zou, O. Iliopoulos   +11 more
semanticscholar   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Pyrimidine Nucleos(t)ide Therapy in Patients With Thymidine Kinase 2 Deficiency: A Multicenter Retrospective Chart Review Study. [PDF]

Neurology
Domínguez-González C, Chiang C, Colson AO, Rebollo Mesa I, Baixauli E, Quan J, VanMeter S, Hirano M.   +7 more
europepmc   +1 more source