Results 221 to 230 of about 314,968 (285)

Pyrimidine-Dependent UV-Mediated Cross-Linking Magnifies Minor Genetic or Epigenetic Changes in Clinical Samples

Fangyan Yu, Farzana Ahmed, Stavroula Smilkou, Sayeda Yasmin‐Karim, Farzaneh Darbeheshti, Athina Markou, Martyn Bullock, Ioannis Boukovinas, Viktor A. Adalsteinsson, Evi Lianidou, G. Mike Makrigiorgos   +10 more
openalex   +2 more sources

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Masaki Tanito   +3 more
wiley   +1 more source

High tide or low tide: the transport and metabolism of mitochondrial nucleotides. [PDF]

Biochem J
MacVicar T.
europepmc   +1 more source

Application of quinazoline and pyrido[3,2-d]pyrimidine templates to design multi-targeting agents in Alzheimer's disease

, 2017
Tarek Mohamed, Mandeep Mann, Praveen P. N. Rao   +2 more
openalex   +2 more sources

Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222‐nm Far ultraviolet C

Photochemistry and Photobiology, EarlyView.
222‐nm Far UV‐C has a bactericidal effect and is less harmful to humans than 254‐nm UV‐C. This study investigated photoreactivation of Staphylococcus aureus irradiated with 222‐nm Far UV‐C. The proliferative effect of 222‐nm UV‐C irradiated S. aureus by photoreactivation was lower than with 254‐nm UV‐C.
Risako Fukushi, Kouji Narita, Kyosuke Yamane, Toru Koi, Krisana Asano, Akio Nakane   +5 more
wiley   +1 more source

Supramolecular Efficient Catalysis for Multicomponent Synthesis of Fused Indeno-pyrido[2,3‑<i>d</i>]pyrimidines as <i>Staphylococcal Thioredoxin Reductase</i> (<i>Sa</i>TrxR) Inhibitor Leads. [PDF]

ACS Omega
Bhosle MR, Belambe AV, Yadav VK, Bhati AS, Talekar SS, Bondle GM, Mane MV, Bhattacharyya S.   +7 more
europepmc   +1 more source

A skin explant model for studying UV‐induced DNA damage and repair

Photochemistry and Photobiology, EarlyView.
The study describes an ex vivo skin model that preserves the natural physiology of the skin while addressing ethical concerns related to animal research. We demonstrate this model maintains key characteristics and physiological responses of in vivo skin during short incubation periods. Moreover, this model requires fewer mice than in vivo testing, thus
Hailey Payne, Christina Athans, Shiyong Wu, Veronica Bahamondes Lorca   +3 more
wiley   +1 more source

ASS1 inhibits liver cancer by promoting CAD ubiquitination and reversing the urea cycle and pyrimidine synthesis imbalance. [PDF]

Hepatol Commun
Ming Z, Luo T, Zou Z, Luo W, Hu X, Chen L, Zhou J, Liu X, Liu M, Li J, Luo J, Ma D, Liu S, Luo Z.   +13 more
europepmc   +1 more source

Deciphering the role of HD52, a mitochondrial nucleotidase essential for pyrimidine homeostasis in Trypanosoma brucei

, 2019
Miriam Yagüe-Capilla, VM Castillo-Acosta, María Valente, Cristina Bosch‐Navarrete, Luis M. Ruiz‐Pérez, Dolores González‐Pacanowska   +5 more
openalex   +1 more source

The pyrimidine biosynthesis operon of the thermophile Bacillus caldolyticus includes genes for uracil phosphoribosyltransferase and uracil permease

, 1994
Sa‐Youl Ghim, Jan Neuhard
openalex   +2 more sources