Results 221 to 230 of about 151,536 (281)

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang   +7 more
wiley   +1 more source

Roles of nucleotide metabolism in pancreatic cancer. [PDF]

open access: yesFront Immunol
Liu Q   +5 more
europepmc   +1 more source

Metformin‐Mediated Glycaemic Regulation as a Potential Strategy for Breast Cancer Prevention

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
Metformin (MET), a common antihyperglycemic drug, shows promising anti‐cancer effects in breast cancer (BC). It activates adenosine monophosphate‐activated protein kinase (AMPK), regulating cellular energy and inducing cell cycle arrest, anti‐proliferation, and microenvironment alterations.
Ambulugala Gamage Rajika Greshamali Jinadasa   +4 more
wiley   +1 more source

Acaricidal activity of small molecule antagonists of the tick kinin receptor against Rhipicephalus microplus acaricide‐susceptible and resistant strains

open access: yesPest Management Science, Volume 82, Issue 2, Page 1618-1628, February 2026.
Two small molecules, SACC‐0039590 and SACC‐0428788, killed cattle fever tick, R. microplus, susceptible Deutch strain and pyrethroid resistant Arauquita strain larvae. SACC‐0039590 at 1 mM decreased the reproductive parameters of Deutch females. Abstract BACKGROUND Resistance to acaricides underscores the need for tick control alternatives.
Waleed M. Arafa   +2 more
wiley   +1 more source

Comparative Study of UVA Filtering Compounds 2‑Methyl/2-Amino Pyrimidine Derivatives of Avobenzone under Acidic Conditions. [PDF]

open access: yesACS Omega
Krishnappa R   +8 more
europepmc   +1 more source

Gut Microbiome Dysbiosis is Associated With Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Infection and Disease Progression to HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis: A Cross‐Sectional Study

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes   +8 more
wiley   +1 more source

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao   +6 more
wiley   +1 more source

From Chains to Chromophores: Tailored Thermal and Linear/Nonlinear Optical Features of Asymmetric Pyrimidine-Coumarin Systems. [PDF]

open access: yesMolecules
Nicolas P   +11 more
europepmc   +1 more source

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