Results 221 to 230 of about 197,991 (343)

Upregulation of ST3GAL5 predicts suppression of malignant biological behavior in bladder cancer

UroPrecision, EarlyView.
Abstract Background Bladder cancer (BLCA) is the most prevalent malignancy in the urinary tract system, while ST3GAL5 is a protein‐coding gene that catalyzes the formation of ganglioside monosialodihexosylganglioside 3 (GM3) synthase. GM3 synthase has been reported to significantly influence the malignant process of various cancers.
Song Ou‐Yang, Lei Tang, Lin Li, Yawei Zhao   +3 more
wiley   +1 more source

Pyrrolopyrimidines: Design, Synthesis and Antitumor Properties of Novel Tricyclic Pyrrolo [2,3-<i>d</i>]pyrimidine Derivatives. [PDF]

Molecules
Song B, Murtazaeva Z, Nie L, Kuryazov R, Gaybullaev S, Niu C, Bozorov K, Aisa HA, Zhao J.   +8 more
europepmc   +1 more source

THE FUNCTION OF OROTIC ACID IN THE BIOGENESIS OF PYRIMIDINES IN SLICES FROM REGENERATING LIVER

, 1952
Peter Reichard
openalex   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

VIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan, Wangzheqi Zhang, Yan Liao, Chenglong Zhu, Xiaojing Guo, Zui Zou, Mi Li   +6 more
wiley   +1 more source

Recent developments in the chemistry and enzyme inhibitory activity of fused thiazoles and thiadiazoles

Vietnam Journal of Chemistry, EarlyView.
Abstract The combination of cyclization reactions of thiadiazoles and benzothiazoles with Pd‐catalyzed cross‐coupling reactions provided a convenient synthesis of annulated, fluorinated and non‐fluorinated heterocycles, such as 1,3,4‐thiadiazolo[3,2‐a]pyrimidin‐5‐ones, benzothiazolo[3,2‐a]pyridimidin‐4‐ones, benzothiazolo[2,3‐b]quinazolin‐12‐ones and ...
Peter Langer
wiley   +1 more source

Analysis of the structural diversity of heterocycles amongst European medicines agency approved pharmaceuticals (2014-2023). [PDF]

RSC Med Chem
Ward M, O'Boyle NM.
europepmc   +1 more source

Hydrazino Derivatives of Pyrimidine. III

, 1955
Den-itsu Shiho, Noboru Takahayashi
openalex   +2 more sources

Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers

Journal of Clinical Investigation, 2017
A. Okazaki, P. Gameiro, Danos C. Christodoulou, Laura Laviollette, Meike Schneider, Frances Chaves, A. Stemmer-Rachamimov, Stephanie A. Yazinski, Richard Lee, G. Stephanopoulos, L. Zou, O. Iliopoulos   +11 more
semanticscholar   +1 more source

Quantifying Soil Microbiome Abundance by Metatranscriptomics and Complementary Molecular Techniques—Cross‐Validation and Perspectives

Molecular Ecology Resources, EarlyView.
ABSTRACT Linking meta‐omics and biogeochemistry approaches in soils has remained challenging. This study evaluates the use of an internal RNA extraction standard and its potential for making quantitative estimates of a given microbial community size (biomass) in soil metatranscriptomics. We evaluate commonly used laboratory protocols for RNA processing,
Mathilde Borg Dahl, Stella Brachmann, Andrea Söllinger, Marina Schnell, Laureen Ahlers, Magdalena Wutkowska, Katharina J. Hoff, Neetika Nath, Verena Groß, Haitao Wang, Micha Weil, Marc Piecha, Marc Schaffer, Corinna Jensen, Andreas W. Kuss, Christoph Gall, Erika Wimmer, Thomas Pribasnig, Alexander Tøsdal Tveit, Bjarni D. Sigurdsson, Christa Schleper, Andreas Richter, Tim Urich   +22 more
wiley   +1 more source

A pyrimidine metabolism-related gene signature for prognosis prediction and immune microenvironment description of breast cancer. [PDF]

J Transl Med
Wang H, Zhou Z, Zhong H, Wang S, Shen K, Huang R, Wang R, Wang Z.   +7 more
europepmc   +1 more source