Dietary phytochemical indole-3-carbinol regulates metabolic reprogramming in mouse prostate tissue. [PDF]
Pharm ResPeter RM +7 more
europepmc +1 more source
A point mutation in IAA34 confers resistance to the auxin herbicide 2,4‐D in Sisymbrium orientale
Pest Management Science, EarlyView.A point mutation in domain IV of SoAux/IAA34‐R provides resistance to 2,4‐D. Abstract BACKGROUND Sisymbrium orientale has evolved resistance to 2,4‐D in Australia due to a 27 bp deletion in SoIAA2. However, one population of Sisymbrium orientale resistant to 2,4‐D (R1) did not contain the SoIAA2Δ27, suggesting another 2,4‐D resistance mechanism was ...
Yuanlin Qi +3 more
wiley +1 more source
mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase. [PDF]
Cell RepPham BQ, Yi SA, Ordureau A, An H.
europepmc +1 more source
Influence of Cosolvents on the Pressure Stability of Human Serum Albumin
physica status solidi (a), EarlyView.Human serum albumin is able to bind various hydrophobic substances and drugs. To investigate this interaction, the protein structure is analyzed using small‐angle X‐ray scattering under high hydrostatic pressure. The resulting radius of gyration (see picture) indicates that hydrophobic substances influence the pressure stability of HSA differently ...
Jaqueline Savelkouls +3 more
wiley +1 more source
Identification of pyrimidine metabolism-based molecular subtypes and prognostic signature to predict immune landscape and guide clinical treatment in prostate cancer. [PDF]
Ann MedYu YZ +11 more
europepmc +1 more source
Small Science, EarlyView.Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos +2 more
wiley +1 more source
Aminoquinoline-Pyrimidine-Based Alkyl-Piperazine Tethered Hybrids: Synthesis, Antiplasmodial Activity, and Mechanistic Studies. [PDF]
ACS OmegaRawat S +6 more
europepmc +1 more source
Recent Advances in Biosensors Based on Hybridization Chain Reaction and Silver Nanoclusters
Small Methods, EarlyView.This review explores the integration of hybridization chain reaction (HCR) with silver nanoclusters (AgNCs) to form hybrid HCR‐AgNCs biosensors, highlighting advancements in their design, performance, and practical applications. It covers recent innovations, methodological improvements, and the potential of HCR‐AgNCs systems as detectors across various
Zheng Wei Wong, Siu Yee New
wiley +1 more source