Results 211 to 220 of about 72,841 (281)

Ultraviolet C (UV‐C) Light Therapy Inhibits Pathogens Associated With Equine Keratomycosis at Different Corneal Depths—An Ex Vivo Study

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To assess if an inexpensive, commercially available ultraviolet C (UV‐C) light device with a peak emission of 275 nm can inhibit equine keratomycosis‐associated pathogens located at different corneal depths in an ex vivo model. Methods A controlled, randomized experimental design.
Mona Hoerdemann, Dipak K. Sahoo, Rachel A. Allbaugh, Melissa A. Kubai   +3 more
wiley   +1 more source

In Vitro Evaluation of Sugar-Conjugated Thienopyrimidinone Derivatives with Possible Neuroprotective and Antioxidant Effects. [PDF]

Int J Mol Sci
Alshamari AK, Aboulthana WM, Mansour H, Abu-Zied KM, Alshammari OAO, Morsy NM, Alsaif NOS, Alshammari MZ, Nossier ES, Hassan NA.   +9 more
europepmc   +1 more source

Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors

, 2019
Benjamin N. Atkinson, David Steadman, William Mahy, Yuguang Zhao, James Sipthorp, Elliott D. Bayle, Fredrik Svensson, George Papageorgiou, Fiona Jeganathan, Sarah E Frew, Amy E. Monaghan, Magda Bictash, E. Yvonne Jones, Paul V. Fish   +13 more
openalex   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

The RNA demethylase FTO promotes glutamine metabolism in clear cell renal cell carcinoma through the regulation of SLC1A5. [PDF]

Sci Adv
Zhao M, Zhang D, Jiang H, Kuganesan N, Natarajan S, Pu L, Thakkar KN, Zhao H, Le QT, Giaccia AJ, Brooks JD, Peehl DM, Ye J, Rankin EB.   +13 more
europepmc   +1 more source

On why cancer cells require a great amount of glucose

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu, Aoran Liu, Rui Shi, Long Xu, Zhenyu Huang, Ye Zhang, Ying Xu   +6 more
wiley   +1 more source

Response of <i>Escherichia coli</i> chemotaxis pathway to pyrimidine deoxyribonucleosides. [PDF]

Microbiol Spectr
Shah M, Xu W, Sourjik V.
europepmc   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

N-acetylaspartate from fat cells regulates postprandial body temperature. [PDF]

Nat Metab
Felix JB, Saha PK, de Groot EL, Tan L, Sharp R, Anaya ES, Li Y, Quang H, Saidi N, Abushamat L, Ballantyne CM, Amos CI, Lorenzi PL, Klein S, Gao X, Hartig SM.   +15 more
europepmc   +1 more source

Adrenal pheochromocytoma impacts three main pathways: cysteine-methionine, pyrimidine, and tyrosine metabolism

Chong Lai, Qingling Yang, Yunuo Zhang, Renjie Gong, Majie Wang, Jiankang Li, Maode Lai, Qingrong Sun   +7 more
openalex   +2 more sources