Results 211 to 220 of about 172,292 (284)
In vitro biological studies and computational prediction-based analyses of pyrazolo[1,5-a]pyrimidine derivatives. [PDF]
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Receptors for Purines and Pyrimidines
Pharmacological Reviews, 1998### A. Overview Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are important signaling molecules that mediate diverse biological effects via cell-surface receptors termed purine receptors.
Vera Ralevic, Geoffrey Burnstock
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Synthetic chemistry of pyrimidines and fused pyrimidines: A review [PDF]
Synthetic Communications, 2016 AbstractReview: 100 refs.
Selvaraj Mohana Roopan, Rajesh Sompalle
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Skeletal Editing of Pyrimidines to Pyrazoles by Formal Carbon Deletion
Journal of the American Chemical Society, 2022 A method for the conversion of pyrimidines into pyrazoles by a formal carbon deletion has been achieved guided by computational analysis. The pyrimidine heterocycle is the most common diazine in FDA-approved drugs, and pyrazoles are the most common ...
Richmond Sarpong
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RSC Advances, 2021 Pyrimidines are aromatic heterocyclic compounds that contain two nitrogen atoms at positions 1 and 3 of the six-membered ring. Numerous natural and synthetic pyrimidines are known to exist.
Adriana Pereira Duarte +2 more
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The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines
Current Topics in Medicinal Chemistry, 2016This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures,
M. S. Sanap +10 more
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Manganese‐Catalyzed Multicomponent Synthesis of Pyrimidines from Alcohols and Amidines
Angewandte Chemie - International Edition, 2017The development of catalytic reactions for synthesizing different compounds from alcohols to save fossil carbon feedstock and reduce CO2 emissions is of high importance. Replacing rare noble metals with abundantly available 3d metals is equally important.
Rhett Kempe, James L Kennedy
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Sustainable Synthesis of Quinolines and Pyrimidines Catalyzed by Manganese PNP Pincer Complexes
Journal of the American Chemical Society, 2016This study represents the first example an environmentally benign, sustainable, and practical synthesis of substituted quinolines and pyrimidines using combinations of 2-aminobenzyl alcohols and alcohols as well as benzamidine and two different alcohols,
Matthias Mastalir +2 more
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Pyrimidines. XIII. Novel pyrimidine to pyrimidine transformation reactions
Journal of Heterocyclic Chemistry, 1977AbstractNovel pyrimidine to pyrimidine transformation reactions are described. 1,3‐Dimethyl‐(or diethyl)‐uracil(1) are converted into isocytosine, 2‐thiouracil or uracil derivatives by treatment with guanidine, thiourea or urea, respectively. The latter two cases require base catalysis. The effects of some substituents at C‐5 and C‐6 of 1,3‐dialkylated
Kyoichi A. Watanabe +2 more
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An overview on synthetic and pharmaceutical prospective of pyrido[2,3‐d]pyrimidines scaffold
Chemical Biology and Drug Design, 2020Pyrido[2,3‐d]pyrimidine, a fused hetero‐bicyclic nucleus containing pyridine and pyrimidine rings has attained the momentary attention in the sphere of multicomponent synthetic protocol and medicinal chemist.
P. Yadav, K. Shah
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