Results 21 to 30 of about 7,405 (269)

A facile synthesis of polysubstituted furo[2,3-d]pyrimidinones and 1,2,4-triazole-fused derivatives

Journal Chemical Research, 2020
In this paper, a series of polysubstituted furo[2,3-d]pyrimidinones, including 1,2,4-triazole-fused derivatives, are synthesized via aza-Wittig reactions of iminophosphoranes, under mild conditions.
Hai-Tao Gao, Jun-Kai Ma, Yanggen Hu, Hong-Mei Wang   +3 more
semanticscholar   +1 more source

Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones [PDF]

, 2009
A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively.
Bernardini, Martina, Botta, Maurizio, Castagnolo, Daniele, Pagano, Mafalda   +3 more
core   +1 more source

Synthesis of 6-Amino-5-cyano-1,4-disubstituted-2(1H)-Pyrimidinones via Copper-(I)-catalyzed Alkyne-azide ‘Click Chemistry’ and Their Reactivity

Molecules, 2010
In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presence of
Fethi Zribi, Romain Duval, Fakher Chabchoub, Françoise Nepveu, Ennaji Najahi, Jan Sudor   +5 more
doaj   +1 more source

1,2,3-Triazolyl-tetrahydropyrimidine Conjugates as Potential Sterol Carrier Protein-2 Inhibitors: Larvicidal Activity against the Malaria Vector Anopheles arabiensis and In Silico Molecular Docking Study

Molecules, 2022
Alteration of insect growth regulators by the action of inhibitors is becoming an attractive strategy to combat disease-transmitting insects. In the present study, we investigated the larvicidal effect of 1,2,3-triazolyl-pyrimidinone derivatives against ...
Katharigatta N. Venugopala, Pottathil Shinu, Christophe Tratrat, Pran Kishore Deb, Raquel M. Gleiser, Sandeep Chandrashekharappa, Deepak Chopra, Mahesh Attimarad, Anroop B. Nair, Nagaraja Sreeharsha, Fawzi M. Mahomoodally, Michelyne Haroun, Mahmoud Kandeel, Syed Mohammed Basheeruddin Asdaq, Viresh Mohanlall, Nizar A. Al-Shar’i, Mohamed A. Morsy   +16 more
doaj   +1 more source

Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis [PDF]

, 2010
Tetrazoles remain a challenge to photochemists. Photolysis leads to cleavage of the tetrazolyl ring, may involve various photodegradation pathways and may produce a diversity of photoproducts, depending on the structure and conformational flexibility of
Amin Ismael, Araujo, Brigas, Butler, Butler, Catalan, Cristiano, Elguero, Gómez-Zavaglia, Gómez-Zavaglia, Katritzky, Koldobskii, Koldobskii, Luís Miguel Teodoro Frija, Maier, Maria Lurdes Santos Cristiano, Moore, Ostrovskii, Ostrovskii   +18 more
core   +2 more sources

Five-Membered Heterocyclic Ring Via Dichalcones [PDF]

مجلة التربية والعلم, 2013
In this study some of dichalcone compounds (4-12) were prepared by the reaction of benzalacetone and its derivatives with a number of different ketones (acetophenone, acetanilide, 2-butanone).
N. Ahmad, O Ali
doaj   +1 more source

Succinimide-N-sulfonic acid as an efficient recyclable catalyst for the synthesis of some fused indolo pyrano pyrimidinone derivatives [PDF]

, 2014
A new, simple, thermally efficient and solvent-free condensation of 2-amino-4,5-dihydro-4-phenylpyrano[3,2-b]indole-3-carbonitrile derivatives with coumarin-3-carboxylic acid employing succinimide-N-sulfonic acid (SuSA) as catalyst for the synthesis of a
Aswin, K., Logaiya, K., P. N. Sudhan, S., S. Mansoor, S.   +3 more
core   +4 more sources

Continuous-flow retro-Diels–Alder reaction: an efficient method for the preparation of pyrimidinone derivatives

Beilstein Journal of Organic Chemistry, 2018
The syntheses of various pyrimidinones as potentially bioactive products by means of the highly controlled continuous-flow retro-Diels–Alder reaction of condensed pyrimidinone derivatives are presented.
Imane Nekkaa, Márta Palkó, István M. Mándity, Ferenc Fülöp   +3 more
doaj   +1 more source

A One-pot Multi-component Synthesis of some New Dihydropyrimidine Derivatives via Biginelli Condensations

Zanco Journal of Pure and Applied Sciences, 2023
The Biginelli Reaction is a one-pot acid catalyzed cyclocondensation of -keto ester, urea and aromatic aldehyde which leads to the synthesis of functionalized 3,4-dihydro-2(H)-pyrimidinones (DHPMs).
Rostam R. Braiem
doaj   +1 more source

Design, Synthesis and Anticancer Activity of New Polycyclic: Imidazole, Thiazine, Oxathiine, Pyrrolo-Quinoxaline and Thienotriazolopyrimidine Derivatives

Molecules, 2021
In this article, we showed the synthesis of new polycyclic aromatic compounds, such as thienotriazolopyrimidinones, N-(thienotriazolopyrimidine) acetamide, 2-mercapto-thienotriazolo-pyrimidinones, 2-(((thieno-triazolopyrimidine) methyl) thio) thieno ...
Ameen Ali Abu-Hashem, Sami A. Al-Hussain, Magdi E. A. Zaki   +2 more
doaj   +1 more source