Results 81 to 90 of about 14,691 (260)
Higginsianins A and B, two fungal diterpenoid α-pyrones with cytotoxic activity against human cancer cells [PDF]
, 2019 Two new diterpenoid α-pyrones, named higginsianins A and B, were isolated from the mycelium of the microbial fungus Colletotrichum higginsianum grown in liquid culture.
Calabrò, Viola +7 more
core +1 more source
T‐Shaped 8‐Aryl(ethynyl)‐Substituted Psoralens With Tunable Charge‐Transfer Absorption
European Journal of Organic Chemistry, Volume 29, Issue 8, 25 February 2026.Starting from 8‐methoxypsoralen, new 8‐arylated and 8‐alkynylated psoralen derivatives are accessible by cross‐coupling. These T‐shaped π‐expanded chromophores are luminescent and photophysics reveal a highly polar excited state with tunable charge‐transfer character.
Lena T. Leusch, Thomas J. J. Müller
wiley +1 more source
A Biosynthetic Numbering System for Diterpene Pyrones
Natural Product Communications, 2019 Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to ...
Amjad Ayad Qatran Al-Khdhairawi +3 more
doaj +1 more source
Two new -Methoxy--Pyrones From the Mangrove Sediment-Derived SCSIO NS126
Natural Product Communications, 2021 Two new α -methoxy- γ -pyrone analogs, 2-methoxy-3-methyl-5,6-diethyl- γ -pyrone ( 2 ) and 2-methoxy-3,5-dimethyl-6-propyl- γ -pyrone ( 3 ), together with 2-methoxy-3,5-dimethyl-6-ethyl- γ -pyrone ( 1 ), firstly isolated from natural sources, were ...
Kunlong Li +6 more
doaj +1 more source
Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]
, 2018 Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael +8 more
core +3 more sources
Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance
Advanced Science, Volume 13, Issue 8, 9 February 2026.Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao +5 more
wiley +1 more source
Isoflavonoids and Epigenetic Modulation: Therapeutic Insights for Cancer Treatment
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.Venn diagram illustrating the epigenetic roles of three phytochemical groups—flavonoids, isoflavonoids, and pterocarpans. ABSTRACT Isolavonoides represent the second largest subgroup of flavonoids and have an influence on critical molecular pathways and restore cellular homeostasis, through the reprogramming of epigenetic regulatory mechanisms.
Eduardo de Moraes e Sousa +8 more
wiley +1 more source
Chemistry of Pyrones, Part 3: New Podands of 4H-Pyran-4-ones
Molecules, 2000 New derivatives of 3,5-disubstituted 4H-Pyran-4-one podands (9-15) were prepared by transesterification reaction of dimethyl or diethyl 2,6-dimethyl-4H-pyran-4-one-3,5-dicarboxylate with some glycol, glycol ethers or by nucleophilic substitution of some ...
Aziz Shahrisa, Alireza Banaei
doaj +1 more source
eFood, Volume 7, Issue 1, February 2026.From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley +1 more source
DEVELOPMENT OF NEW ACCESS ROUTES TO PYRAZOLO[1,5-a]PYRIMIDINE USING 4-HYDROXY-6-METHYLPYRAN-2-ONE
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2011 In this work, we propose a new and fast strategy giving the pyrazolo[1,5-a]pyrimidines substituted at positions 5 and 7 via condensation of 3-amino-5-arylpyrazoles with 2-hydroxy-6-methylpyran-2-one in both conventional heating and microwave irradiation.
El Mokhtar Essassi +3 more
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