Results 171 to 180 of about 81,237 (352)

Synthesis, Anticonvulsant Properties, and SAR Analysis of Differently Substituted Pyrrolidine‐2,5‐diones and Piperidine‐2,6‐diones

, 2014
Krzysztof Kamiński, Beata Wiklik, Jolanta Obniska   +2 more
openalex   +2 more sources

Tracking Propagating Perturbations in Chemical Reactions

ChemistryEurope, Volume 4, Issue 1, January 2026.
Tracking the propagation of periodic concentration perturbations within chemical reactions is presented as a powerful strategy for probing reaction connectivity and the kinetics of individual reaction steps. This approach is demonstrated here for the organocatalytic Michael‐type addition of cyclopentadiene to α,β‐unsaturated aldehydes, based on ...
Charlotte Lefebvre, Quentin Duez
wiley   +1 more source

Well‐Defined Rhodium and Iridium Complexes Containing Chiral Cyclic(Alkyl)(Amino)Carbenes for Asymmetric Hydrogenation

ChemistryEurope, Volume 4, Issue 1, January 2026.
A set of fourteen well‐defined rhodium and iridium complexes containing various enantiopure cyclic(alkyl)(amino)carbene (ChiCAAC) ligands (>96% ee to > 99.5% ee) has been synthesized and fully characterized. While no enantioselectivity is observed with chiral Rh‐CAAC, the Ir‐CAAC counterparts demonstrated good performances in the asymmetric ...
Fanny Morvan, Meng Liu, Thomas Vives, Thierry Roisnel, Nicolas Vanthuyne, Rodolphe Jazzar, Joanna Wencel‐Delord, Marc Mauduit   +7 more
wiley   +1 more source

Palladium-catalyzed, pyrrolidine-mediated arylmethylation of ketones and aldehydes with coumarinyl(methyl) acetates

, 2012
Kalicharan Cattopadhyay, Antonio Recio, Jon A. Tunge   +2 more
openalex   +2 more sources

Unlocking Biomolecule Modification with Light‐Promoted Photocatalyst‐Free Approaches: Current Tools, Challenges, and Perspectives

ChemistryEurope, Volume 4, Issue 1, January 2026.
This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink, Maria Eduarda C. Thedy, Eugénie Romero, Gary A. Molander   +3 more
wiley   +1 more source

Synthesis and Reactions of Pyrrolidine Derivatives from Succinimide

, 1982
Tatsuo Nagasaka, Fumiko Hamaguchi, N. OZAWA, Yoshiyuki Kosugi, Sayuri Esumi, S. OHKI   +5 more
openalex   +1 more source

Design, Synthesis, Molecular Docking and in vitro Evaluation ofN-(4-Ethoxyphenylsulfonyl)pyrrolidine-2-carboxylic Acid Analogues asAntiangiogenic and Anticancer Agents on Multiple Myeloma

, 2021
Avijit Ghosh, Abhijit Saha, Koushik Sarker, Suvasish Mishra, Subrata Sen   +4 more
openalex   +1 more source

Development of New Benzo[b]Thiophene‐2‐Carboxamide Derivatives as Advanced Glycation End‐Products Receptor (RAGE) Antagonists

ChemMedChem, Volume 21, Issue 1, January 2026.
A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin, Matthieu Hedouin, Christophe Furman, Ophélie Not, Steve Lancel, Mona Bensalah, Gael Coadou, Eric Boulanger, Sergiu Shova, Hassan Oulyadi, Alina Ghinet   +10 more
wiley   +1 more source

Tetrasubstituted Pyrrolidines via a Tandem Aza‐Payne/Hydroamination Reaction.

, 2007
Jennifer M. Schomaker, Andrea R. Geiser, Rui Huang, Babak Borhan   +3 more
openalex   +2 more sources

Pyrrolidine Dithiocarbamate Suppresses Cutibacterium acnes-Induced Skin Inflammation [PDF]

, 2023
Jin Hak Shin, Seon Sook Kim, Su Ryeon Seo   +2 more
openalex   +1 more source