Results 51 to 60 of about 70,546 (390)

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions

Beilstein Journal of Organic Chemistry, 2015
Stable heterocyclic hydroperoxide can be easily prepared as a product of fast oxidation of a 1,2,3,4-tetrahydropyridine by 3O2 if the solution is exposed to sunlight.
Baiba Turovska, Henning Lund, Viesturs Lūsis, Anna Lielpētere, Edvards Liepiņš, Sergejs Beljakovs, Inguna Goba, Jānis Stradiņš   +7 more
doaj   +1 more source

A mechanochemical approach to access the proline–proline diketopiperazine framework

Beilstein Journal of Organic Chemistry, 2017
Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides ...
Nicolas Pétry, Hafid Benakki, Eric Clot, Pascal Retailleau, Farhate Guenoun, Fatima Asserar, Chakib Sekkat, Thomas-Xavier Métro, Jean Martinez, Frédéric Lamaty   +9 more
doaj   +1 more source

Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.02,6]decane skeleton

Beilstein Journal of Organic Chemistry, 2009
An enantioselective route to four tricyclic amino acids and N-tosylamides, composed of a central norbornane framework with a 2-endo,3-endo-annelated pyrrolidine ring and a 5-endo-C1 or -C2 side chain, has been developed. A key intermediate was the chiral,
Matthias Breuning, Tobias Häuser, Christian Mehler, Christian Däschlein, Carsten Strohmann, Andreas Oechsner, Holger Braunschweig   +6 more
doaj   +1 more source

Crystal structure of (1′S,2′S,3S)-1′-benzoyl-2′-(4-methoxyphenyl)-1-methyl-2′,5′,6′,10b′-tetrahydro-1′H-spiro[indoline-3,3′-pyrrolo[2,1-a]isoquinolin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2020
In the title spiro compound, C34H30N2O3, the central pyrrolidine ring is fused with the tetrahydroisoquinoline ring, both having distorted envelope conformations, with the flap atoms being C and N, respectively. The methoxyphenyl group is attached to the
Janet Priyavathani Selvaraj, Stella Mary, Jyoti Boruah Dhruba, Birkumar Singh Huidrom, Yuvaraj Panneerselvam, Kannan Piskala Subburaman   +5 more
doaj   +1 more source

Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination [PDF]

, 2010
Gold-ilocks and the 3 mol % catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant.
Benitez, Diego, Brenzovich, William E., Jr., Goddard, William A., III, Lackner, Aaron D., Shunatona, Hunter P., Tkatchouk, Ekaterina, Toste, F. Dean   +6 more
core   +1 more source

5′′-Benzylidene-5-chloro-1′,1′′-dimethyl-4′-phenyldispiro[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

Acta Crystallographica Section E, 2014
The title compound, C30H28ClN3O2, features two spiro links, one connecting the piperidine and pyrrolidine rings, and the other connecting the pyrrolidine ring and indole residue. The configuration about the ethene bond is E.
I. S. Ahmed Farag, Adel S. Girgis, A. A. Ramadan, A. M. Moustafa, Edward R. T. Tiekink   +4 more
doaj   +1 more source

Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
The present study describes the synthesis of a novel series of thiazolidin-4-one and thiazinan-4-one using 1-(2-aminoethyl)pyrrolidine as amine precursor. All compounds were synthesised by one-pot three component cyclocondensation reaction from the amine,
Adriana M. das Neves, Gabriele A. Berwaldt, Cinara T. Avila, Taís B. Goulart, Bruna C. Moreira, Taís P. Ferreira, Mayara S. P. Soares, Nathalia S. Pedra, Luiza Spohr, Anita A. A. dE Souza, Roselia M. Spanevello, Wilson Cunico   +11 more
doaj   +1 more source

N-Sulfinylpyrrolidine-containing ureas and thioureas as bifunctional organocatalysts

Beilstein Journal of Organic Chemistry, 2021
The synthesis of bifunctional N-sulfinylureas and thioureas with an appended pyrrolidine unit is presented. These organocatalysts were evaluated in Michael additions of aldehydes to nitroalkenes both under solvent-free conditions and in solution.
Viera Poláčková, Dominika Krištofíková, Boglárka Némethová, Renata Górová, Mária Mečiarová, Radovan Šebesta   +5 more
doaj   +1 more source

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

Journal of Neuroinflammation, 2016
BackgroundEndogenous defense against oxidative stress is controlled by nuclear factor erythroid 2-related factor 2 (Nrf2). The normal compensatory mechanisms to combat oxidative stress appear to be insufficient to protect against the prolonged exposure ...
J. R. Liddell, Š. Lehtonen, Clare Duncan, V. Keksa-Goldsteine, A. Levonen, G. Goldsteins, T. Malm, Anthony R. White, J. Koistinaho, K. Kanninen   +9 more
semanticscholar   +1 more source

Diquaternary Ammonium Compounds in Zeolite Synthesis: Cyclic and Polycyclic N-Heterocycles Connected by Methylene Chains [PDF]

, 2009
An additional dimension has been added to our long-standing studies in high silica zeolite synthesis via a guest/host synergism. We have created and studied the impact of making symmetric diquaternary ammonium compounds, by varying the chain length ...
Burton, Allen W., Hwang, Son-Jong, Jackowski, Anna, Zones, Stacey I.   +3 more
core   +1 more source