Results 31 to 40 of about 54,719 (255)

A mechanochemical approach to access the proline–proline diketopiperazine framework

Beilstein Journal of Organic Chemistry, 2017
Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides ...
Nicolas Pétry, Hafid Benakki, Eric Clot, Pascal Retailleau, Farhate Guenoun, Fatima Asserar, Chakib Sekkat, Thomas-Xavier Métro, Jean Martinez, Frédéric Lamaty   +9 more
doaj   +1 more source

Vibrational signatures of gaseous Meisenheimer complexes bonded at carbon and nitrogen [PDF]

, 2017
Anionic adducts of 1,3,5-trinitrobenzene (TNB) with deprotonated pyrrolidine (Pyr), imidazole (Im), acetone (Ac) and acetylacetone (Acac) have been delivered into the gas phase by electrospray ionization.The so-formed ions, TNB-Nu−(Nu = Pyr, Im, Ac, Acac)
Chiavarino, Barbara, Crestoni, Maria Elisa, Fornarini, Simonetta   +2 more
core   +1 more source

Crystal structure and Hirshfeld surface analysis of 4′-(2-chlorophenyl)-1′-methyl-3′′-phenyl-7′′,8′′-dihydro-5′′H-dispiro[indoline-3,2′-pyrrolidine-3′,6′′-isoquinoline]-2,5′′-dione

Acta Crystallographica Section E: Crystallographic Communications, 2018
In the title dispiro compound, C32H26ClN3O2, the cyclohexanone ring of the isoquinoline unit has a distorted envelope conformation, with the methylene C atom adjacent to the spiro C atom as the flap.
R. Vishnupriya, C. Selva Meenatchi, J. Suresh, R. V. Sumesh, R. Ranjith Kumar, P. L. Nilantha Lakshman   +5 more
doaj   +1 more source

One-Pot Synthesis, X-ray Single Crystal and Molecular Insight of Enaminone-Based β-Morpholino-/N-Methylpiperazinyl-/Pyrrolidinylpropiophenone

Crystals, 2020
One-pot synthesis of three enaminones, (E)-1-(4-chlorophenyl)-3-morpholinoprop-2-en-1-one 1, (E)-1-(4-chlorophenyl)-3-(4-methylpiperazin-1-yl)prop-2-en-1-one 2, and (E)-1-(4-chlorophenyl)-3-(pyrrolidin-1-yl)prop-2-en-1-one 3 were achieved.
Assem Barakat, Saied M. Soliman, Matti Haukka, Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, M. Ali, Mohammed Rafi Shaik   +6 more
doaj   +1 more source

Nickel-catalyzed transamidation of aliphatic amide derivatives. [PDF]

, 2017
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained ...
Baker, Emma L, Dander, Jacob E, Garg, Neil K   +2 more
core   +1 more source

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions

Beilstein Journal of Organic Chemistry, 2015
Stable heterocyclic hydroperoxide can be easily prepared as a product of fast oxidation of a 1,2,3,4-tetrahydropyridine by 3O2 if the solution is exposed to sunlight.
Baiba Turovska, Henning Lund, Viesturs Lūsis, Anna Lielpētere, Edvards Liepiņš, Sergejs Beljakovs, Inguna Goba, Jānis Stradiņš   +7 more
doaj   +1 more source

Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C30H23N3O4, the central 1-methylpyrrolidine ring adopts a twist conformation on the N—CH2 bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and
Sadasivam Mathusalini, Vijayan Viswanathan, Palathurai Subramaniam Mohan, Chia-Her Lin, Devadasan Velmurugan   +4 more
doaj   +1 more source

1-Ethyl 2-methyl 3,4-bis(acetyloxy)pyrrolidine-1,2-dicarboxylate: crystal structure, Hirshfeld surface analysis and computational chemistry

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C13H19NO8, is based on a tetra-substituted pyrrolidine ring, which has a twisted conformation about the central C—C bond; the Cm—Ca—Ca—Cme torsion angle is 38.26 (15)° [m = methylcarboxylate, a = acetyloxy and me = methylene].
Sofia Dallasta Pedroso, Ignez Caracelli, Julio Zukerman-Schpector, Monica Soto-Monsalve, Regina H. De Almeida Santos, Carlos Roque D. Correia, Ariel L. Llanes Garcia, Huey Chong Kwong, Edward R. T. Tiekink   +8 more
doaj   +1 more source

Nickel‐Catalyzed Enantioconvergent Arylation of Unactivated Cyclic Electrophiles: Asymmetric Synthesis of 3‐Substituted Pyrrolidines

Angewandte Chemie, EarlyView.
Metal‐catalyzed enantioconvergent substitutions of unactivated cyclic electrophiles by organometallic nucleophiles have not previously been reported. Herein, a chiral nickel catalyst is described that achieves this objective, coupling 3‐iodopyrrolidine derivatives with arylzinc nucleophiles.
Ting Hei Matthew Wong, Xiaoyu Tong, Gregory C. Fu   +2 more
wiley   +2 more sources

Syn-Ethyl 1-hydroxy-7-methoxy-2,3-dihydro-1H-pyrrolo[3,4-b]quinolone-3-carboxylate HCl Salt

Molbank, 2015
This short note describes a one-step synthesis of the title compound from commercially available starting materials and reports its full spectroscopic characterization data.
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source