Results 41 to 50 of about 55,156 (263)

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions

Beilstein Journal of Organic Chemistry, 2015
Stable heterocyclic hydroperoxide can be easily prepared as a product of fast oxidation of a 1,2,3,4-tetrahydropyridine by 3O2 if the solution is exposed to sunlight.
Baiba Turovska, Henning Lund, Viesturs Lūsis, Anna Lielpētere, Edvards Liepiņš, Sergejs Beljakovs, Inguna Goba, Jānis Stradiņš   +7 more
doaj   +1 more source

Crystal structure of 4′-(2-methoxyquinolin-3-yl)-1′-methyldispiro[indan-2,2′-pyrrolidine-3′,3′′-indoline]-1,3,2′′-trione

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C30H23N3O4, the central 1-methylpyrrolidine ring adopts a twist conformation on the N—CH2 bond. The pyrrolidin-2-one ring of the indolin-2-one ring system also has a twist conformation on the C—C bond involving the spiro C atom and
Sadasivam Mathusalini, Vijayan Viswanathan, Palathurai Subramaniam Mohan, Chia-Her Lin, Devadasan Velmurugan   +4 more
doaj   +1 more source

1-Ethyl 2-methyl 3,4-bis(acetyloxy)pyrrolidine-1,2-dicarboxylate: crystal structure, Hirshfeld surface analysis and computational chemistry

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C13H19NO8, is based on a tetra-substituted pyrrolidine ring, which has a twisted conformation about the central C—C bond; the Cm—Ca—Ca—Cme torsion angle is 38.26 (15)° [m = methylcarboxylate, a = acetyloxy and me = methylene].
Sofia Dallasta Pedroso, Ignez Caracelli, Julio Zukerman-Schpector, Monica Soto-Monsalve, Regina H. De Almeida Santos, Carlos Roque D. Correia, Ariel L. Llanes Garcia, Huey Chong Kwong, Edward R. T. Tiekink   +8 more
doaj   +1 more source

Syn-Ethyl 1-hydroxy-7-methoxy-2,3-dihydro-1H-pyrrolo[3,4-b]quinolone-3-carboxylate HCl Salt

Molbank, 2015
This short note describes a one-step synthesis of the title compound from commercially available starting materials and reports its full spectroscopic characterization data.
Marcus Baumann, Ian R. Baxendale
doaj   +1 more source

Nickel-catalyzed transamidation of aliphatic amide derivatives. [PDF]

, 2017
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained ...
Baker, Emma L, Dander, Jacob E, Garg, Neil K   +2 more
core   +1 more source

Glycine-Based [3+2] Cycloaddition for the Synthesis of Pyrrolidine-Containing Polycyclic Compounds

Molecules
The synthesis of pyrrolidine compounds with biological interest is an active research topic. Glycine could be a versatile starting material for making pyrrolidine derivatives.
Tieli Zhou, Xiaofeng Zhang, Desheng Zhan, Wei Zhang   +3 more
doaj   +1 more source

Crystal structure of 3′-(1H-indole-3-carbonyl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro[indoline-3,2′-pyrrolidine]-3′-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C31H22N4O4, the pyrrolidine ring adopts a twist conformation on the N—CH2 bond. The indolin-2-one and the 1H-indole rings are nearly planar (r.m.s.
M. P. Savithri, R. Raja, D. Kathirvelan, B. S. R. Reddy, A. SubbiahPandi   +4 more
doaj   +1 more source

Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
The treatment of neuropathic pain is one of the urgent unmet medical needs and T-type calcium channels are promising therapeutic targets for neuropathic pain.
Hak Kyun Yang, Woo Seung Son, Keon Seung Lim, Gun Hee Kim, Eun Jeong Lim, Changdev G. Gadhe, Jae Yeol Lee, Kyu-Sung Jeong, Sang Min Lim, Ae Nim Pae   +9 more
doaj   +1 more source

Crystal structure of (−)-(5R,7R,8S,9R,10S)-8-methyl-7-[(5R)-3-methyl-2-oxooxolan-3-en-5-yl]-1-aza-6-oxatricyclo[8.3.0.05,9]tridecan-13-one monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The title compound, C17H23NO4·H2O, is an epimer of the natural tetracyclic alkaloid isosaxorumamide which consists of a fused 5–7–5 tricyclic core and a dihydrofuranone substituent.
Takeshi Oishi, Makoto Yoritate, Takaaki Sato, Noritaka Chida   +3 more
doaj   +1 more source

Purification and structure elucidation of three naturally bioactive molecules from the new terrestrial Streptomyces sp. TN17 strain [PDF]

, 2011
Thirty litres of fermentation broth was extracted from the newly isolated Streptomyces sp. strain TN17 and various separation and purification steps led to the isolation of three pure bioactive compounds (1–3).
Coppel, Yannick, Fourati Ben Fguira, Lilia, Lebrihi, Ahmed, Mathieu, Florence, Mellouli, Lofti, Smaoui, Slim   +5 more
core   +2 more sources