Results 71 to 80 of about 55,156 (263)
IUCrData, 2016 In the title solvate, C35H25ClN2O3·0.5CH3OH, the conformation of the central 1-methylpyrrolidine ring is best described as an envelope with the N atom as the flap.
J. M. Joseph +2 more
doaj +1 more source
Stereochemical Studies on a New Ciramadol Analogue by NMR-Spectroscopy [PDF]
, 1994 The absol. configuration of a Ciramadol analogue obtained from (-)-menthone is established by 'H-NMR-. simulated NMR-, COSY-90-, and NOEmeasurements. The final compound 2-(a-1 -pyrrolidino)benzy 1-4-isopropyl- 1 -methyl-cyclohexan-3-one (4b), e.g..
Akgün, H. +4 more
core
Ethyl 1-benzyl-1,2,3,3a,4,10b-hexa-hydro-pyrrolo-[2',3':3,4]pyrrolo-[1,2-a]benzimidazole-2-carboxyl-ate. [PDF]
, 2011 The title mol-ecule, C(22)H(23)N(3)O(2), was obtained via an intra-molecular cyclo-addition of an azomethine ylide and an alkene tethered by a benzimidazole unit. The benzoimidazole unit is essentially planar, with an r.m.s.
Fettinger, James C +2 more
core +2 more sources
Insights into the mechanism for gold catalysis: behaviour of gold(i) amide complexes in solution [PDF]
, 2013 We report the synthesis and activity of new mononuclear and dinuclear gold amide complexes . The dinuclear complexes and were characterised by single crystal X-ray analysis.
Alker +34 more
core +1 more source
Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]
, 2017 The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto +5 more
core +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2019 The title compound, C35H27ClN4O3, crystallized with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran and pyridine rings adopt envelope and chair conformations, respectively.
S. Syed Abuthahir +4 more
doaj +1 more source
Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines [PDF]
, 2014 The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
Antonow +9 more
core +2 more sources
Chemistry – A European Journal, EarlyView.5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
Novel sulfur and selenium containing bis-α-amino acids from 4-hydroxyproline [PDF]
, 2010 The synthesis of new substituted prolines carrying at C-4 a second α-amino acid residue is reported. The amino acid, l-cysteine or l-selenocysteine, is linked to the proline ring through the sulfur or the selenium atom, respectively.
CAPUTO, ROMUALDO +4 more
core +1 more source