Results 71 to 80 of about 13,199 (173)

Asymmetric Synthesis of Polyfunctionalized Pyrrolidines from Sulfinimine-Derived Pyrrolidine 2-Phosphonates. Synthesis of Pyrrolidine 225C

, 2016
The Horner−Wadsworth−Emmons reaction of aldehydes with sulfinimine-derived 3-oxo pyrrolidine phosphonates represents a new method for the asymmetric synthesis of ring-functionalized cis-2,5-disubstituted 3-oxo ...
Franklin A. Davis (2108398), Junyi Zhang (290426), He Xu (147776), Yongzhong Wu (697252)   +3 more
core   +3 more sources

Photochromic Donor–Acceptor Naphthalenediimides Enabling Near‐Infrared Photothermal Conversion for Seawater Desalination

Chemistry – A European Journal, EarlyView.
Photoinduced radical formation in donor–acceptor NDI molecules generates strong near‐infrared absorption, enabling efficient photothermal conversion and solar‐driven seawater desalination. ABSTRACT Photochromic donor–acceptor molecules that produce near‐infrared (NIR) absorption upon light activation offer promising platforms for organic photothermal ...
Sotaro Kusumoto, Soushi Kurihara, Masaya Shimabukuro, Naoki Ogiwara, Nobutsugu Hamamoto, Jack Harrowfield, Yang Kim, Yoshihiro Koide   +7 more
wiley   +1 more source

Ambient temperature zincation of N-Boc pyrrolidine and its solvent dependency

, 2012
Sodium TMP-zincate, [(TMEDA)Na(TMP)(Bu-t)Zn(Bu-t)], can deproto-zincate N-Boc pyrrolidine at ambient temperature in hexane solution, whereas in toluene the captured alpha-carbanion of the heterocycle attacks the solvent setting off a cascade of reactions
Garden, Jennifer A., Mulvey, Robert E., Kennedy, Alan R., Robertson, Stuart D.   +3 more
core   +3 more sources

5-Chloro-5′′-(4-chlorobenzylidene)-4′-(4-chlorophenyl)-1′′-ethyl-1′-methyldispiro[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione

Acta Crystallographica Section E, 2014
Two spiro links are found in the title compound, C31H28Cl3N3O2, one connecting the piperidine and pyrrolidine rings, and the other connecting the pyrrolidine ring and indole residue.
I. S. Ahmed Farag, Adel S. Girgis, A. A. Ramadan, A. M. Moustafa, Edward R. T. Tiekink   +4 more
doaj   +1 more source

Pyrrolidine Inhibitors of Human Cytosolic Phospholipase A₂

, 2016
Pyrrolidine Inhibitors of Human Cytosolic Phospholipase ...
Tomoyuki Ogawa (3024411), Takashi Ono (520294), Shin-ichiro Hara (3024435), Fumihiko Watanabe (3021447), Yasushi Murakami (2052799), Makoto Kii (3023577), Masaaki Wada (3024429), Kaoru Seno (3024420), Tetsuo Okada (1432183), Shozo Nakamoto (3024417), Yasuhiko Fujii (2469802), Hiroshi Hashizume (188480), Mitsuaki Ohtani (3015495), Katsutoshi Yamada (3024423), Isao Teshirogi (3024426), Sanji Hagishita (3023565), Takayuki Okuno (3024408), Yukiko Chikazawa (3024414), Koichi Nishi (2145793), Takaharu Matsuura (3004341), Masahiko Ueno (3024432), Masaaki Yamada (3024405)   +21 more
core   +1 more source

A Solid‐Phase Approach to Chiral C2‐Substituted Cyclen and DOTA‐Like Lanthanoid Ligands

Chemistry – A European Journal, EarlyView.
Chiral C2‐substituted cyclen derivatives have been designed and synthesized from chiral cyclic peptoids. Their conversion into the corresponding DOTA‐type ligands opens new avenues for the development of high‐relaxivity MRI contrast agents. ABSTRACT Magnetic resonance imaging (MRI) is a powerful diagnostic modality that relies on Gd+3‐based contrast ...
Rosaria Schettini, Roberta Napolitano, Alberto Fringuello Mingo, Federica Buonsanti, Giovanni Pierri, Consiglia Tedesco, Chiara Costabile, Giorgio Della Sala, Irene Izzo, Francesco De Riccardis   +9 more
wiley   +1 more source

Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1

EcoEnergy, EarlyView.
A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang, Fangshu Han, Yamin Dong, Liangting Wu, Wenchao Tang, Changyan Guo, Jide Wang, Ablimit Abdukader, Chenjiang Liu, Yonghong Zhang   +9 more
wiley   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source

A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones

Molecules, 2012
A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure.
Rositca D. Nikolova, Nevena I. Petkova, Eleonora D. Ilieva   +2 more
doaj   +1 more source

Nucleophilic Reactions of Cyclobutenones and the Related 4,4‐Dichlorocyclobutenone Derivatives

European Journal of Organic Chemistry, EarlyView.
Cyclobutenone derivates and their 4,4‐dichloro counterparts have an uninterrupted attention as useful synthons in the synthesis of complex organic molecules. Their nucleophilic reactions remain underexplored. This review brings attention to these reactions, whose outcome is not straightforward.
Sarah J. Wright, Muhluri H. Mthombeni, Songeziwe Ntsimango   +2 more
wiley   +1 more source