Results 111 to 120 of about 36,836 (288)
Silyl-substituted pyrrolidines have gained increased interest for the design of new catalyst scaffolds. The molecular structures of four enantiomerically-pure 2-silylpyrrolidinium salts are reported.
Jonathan O. Bauer, Carsten Strohmann
doaj +1 more source
2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone serves as a versatile oxidant and redox catalyst for CC bond formation through hydride abstraction or single‐electron transfer. Stoichiometric and catalytic systems enable benzylic, allylic, and aromatic CH activation under mild, metal‐free conditions, providing sustainable routes to complex and bioactive ...
Dohoon Cha, Sun‐Joon Min
wiley +1 more source
Metal-mediated intramolecular hydroamination and hydro(acy)alkoxylation reactions [PDF]
This PhD thesis describes work undertaken to effect asymmetric catalysis in hydroamination and hydro(acy)alkoxylation reactions of allenes. The introductory Chapter provides an overview of recent advances in asymmetric heterofunctionalisation reactions ...
Arbour, Jannine Louise +1 more
core +1 more source
Energy Economical Annulation Reaction of 1,6‐Enynes with Thiosulfonates (Selenosulfonates): Efficient Synthesis of Multisubstituted Pyrrolidine Derivatives under Room Temperature [PDF]
Jing Yang +6 more
openalex +1 more source
This article presents the synthesis of new derivatives of spirooxindole-spiropiperidinone- pyrrolidines 6a–j and spirooxindole-spiropiperidinone-pyrrolizines 8a–j, through a 1,3-dipolar cycloaddition reaction of azomethineylides generated from isatin ...
Huwaida M. E. Hassaneen +4 more
doaj +1 more source
Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer
ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán +9 more
wiley +1 more source
Iodoaminations of alkenes [PDF]
The activation of alkenes and their subsequent functionalization is a frequently used methodology in synthetic chemistry. This review highlights recent iodine-mediated aminations and elaborates on the various strategies to bring about regio- or ...
Mizar, Pushpak, Wirth, Thomas
core +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Five-membered iminocyclitol a-glucosidase inhibitors: Synthetic,biological screening and in silico studies [PDF]
The design and synthesis of a small library of pyrrolidine iminocyclitol inhibitors with a structural similarity to 1,4-dideoxy-1,4-imino-D-arabitol (DAB-1) is reported.
Burke, A J +7 more
core +1 more source
A radical cascade process involving the activation of two aliphatic C–H bonds in a series of five elementary steps converts readily available terminal alkynes into functionalized cyclopentylmethyl arylsulfones. The methodology delivers flexible synthetic intermediates and was applied to the preparation of diquinanes and triquinanes possessing a rare ...
Lise Benoist +4 more
wiley +2 more sources

