Results 21 to 30 of about 4,162 (161)

Biosynthesis of proline in Pseudomonas aeruginosa. Properties of ;-glutamyl phosphate reductase and 1-pyrroline-5-carboxylate reductase [PDF]

Biochemical Journal, 1979
γ-Glutamyl phosphate reductase, the second enzyme of proline biosynthesis, catalyses the formation of l-glutamic acid 5-semialdehyde from γ-glutamyl phosphate with NAD(P)H as cofactor. It was purified 150-fold from crude extracts of Pseudomonas aeruginosa PAO 1 by DEAE-cellulose chromatography and hydroxyapatite adsorption chromatography. The partially
Krishna, Rangachar V., Beilstein, Paul, Leisinger, Thomas   +2 more
openaire   +3 more sources

Evolution of plant δ1-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives [PDF]

Frontiers in Plant Science, 2015
Proline plays a crucial role in cell growth and stress responses, and its accumulation is essential for the tolerance of adverse environmental conditions in plants. Two routes are used to biosynthesize proline in plants. The main route uses glutamate as a precursor, while in the other route proline is derived from ornithine.
FORLANI, Giuseppe, Makarova, Kira S, Ruszkowski, Milosz, BERTAZZINI, Michele, Nocek, Boguslaw   +4 more
openaire   +4 more sources

Functional Characterization of Four Putative δ1-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis [PDF]

Frontiers in Microbiology, 2017
In most living organisms, the amino acid proline is synthesized starting from both glutamate and ornithine. In prokaryotes, in the absence of an ornithine cyclodeaminase that has been identified to date only in a small number of soil and plant bacteria, these pathways share the last step, the reduction of δ1-pyrroline-5-carboxylate (P5C) catalyzed by ...
Giuseppe Forlani, Boguslaw Nocek, Srinivas Chakravarthy, Srinivas Chakravarthy, Andrzej Joachimiak   +4 more
openaire   +3 more sources

Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers [PDF]

Carcinogenesis, 2017
Human mitochondrial pyrroline-5-carboxylate reductase (PYCR) is a house-keeping enzyme that catalyzes the reduction of Δ1-pyrroline-5-carboxylate to proline. This enzymatic cycle plays pivotal roles in amino acid metabolism, intracellular redox potential and mitochondrial integrity.
Jiefeng, Ding, Mei-Ling, Kuo, Leila, Su, Lijun, Xue, Frank, Luh, Hang, Zhang, Jianghai, Wang, Tiffany G, Lin, Keqiang, Zhang, Peiguo, Chu, Shu, Zheng, Xiyong, Liu, Yun, Yen   +12 more
openaire   +2 more sources

Proline metabolism-related gene expression in four potato genotypes in response to drought stress

Biologia Plantarum, 2019
Drought severely limits potato yield. The aim of this work was to study a response of plantlets of four potato genotypes to polyethylene glycol (PEG 6000)-induced drought stress in both physiological and molecular levels. The drought-tolerant and drought-
Y. LIU, L. WANG, Y. LI, X. LI, J. ZHANG
doaj   +1 more source

Signaling molecule glutamic acid initiates the expression of genes related to methylglyoxal scavenging and osmoregulation systems in maize seedlings

Plant Signaling & Behavior, 2022
Glutamic acid (Glu) is not only a protein amino acid, but also a signaling molecule, which takes part in various physiological processes in plants. Our previous study found that root-irrigation with Glu could improve the heat tolerance of maize seedlings
Xue-Mei Qiu, Yu-Ying Sun, Zhong-Guang Li
doaj   +1 more source

Functional Characterization of Saccharomyces cerevisiae P5C Reductase, the Enzyme at the Converging Point of Proline and Arginine Metabolism

Microorganisms, 2022
The enzyme that, in Saccharomyces cerevisiae, catalyzes the last step in both proline synthesis and arginine catabolism, δ1-pyrroline-5-carboxylate (P5C) reductase, was purified to near homogeneity and characterized thoroughly.
Giuseppe Forlani, Giuseppe Sabbioni, Milosz Ruszkowski   +2 more
doaj   +1 more source

Overexpression of IbMIPS1 gene enhances salt tolerance in transgenic sweetpotato

Journal of Integrative Agriculture, 2016
: Myo-inositol-1-phosphate synthase (MIPS) is a key rate limiting enzyme in the de novo biosynthesis of myo-inositol in plants. In the present study, the IbMIPS1 gene was introduced into sweetpotato cultivar Xushu 18 and the transgenic plants exhibited ...
Fei-bing WANG, Hong ZHAI, Yan-yan AN, Zeng-zhi SI, Shao-zhen HE, Qing-chang LIU   +5 more
doaj   +1 more source

PYCR1 is associated with papillary renal cell carcinoma progression

Open Medicine, 2019
We aimed to determine the function of pyrroline-5-carboxylate reductase 1 (PYCR1) on progression of papillary renal cell carcinoma (PRCC) and related mechanism.
Wang Qiu-Li, Liu Ling
doaj   +1 more source

Gene Cloning and Expression of the Pyrroline-5-carboxylate Reductase Gene of Perennial Ryegrass (Lolium perenne)

Horticultural Plant Journal, 2015
Salt and drought limit the range of applications of perennial ryegrass (Lolium perenne L.), which is one of the important turf and forage grasses. Previous studies have suggested that pyrroline-5-carboxylate reductase (P5CR) might play a central role in ...
Cao Li, Wei Shuqiang, Han Lei, Qian Yongqiang, Zhang Huali, Xin Haibo, Sun Zhenyuan   +6 more
doaj   +1 more source