Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. [PDF]
, 2015 Sirtuin (Sirt) 1 and Sirt 3 are nicotinamide adenine dinucleotide ((+))-dependent protein deacetylases that are important to a number of mitochondrial-related functions; thus, identification of sirtuin activators is important. Herein, we hypothesize that
Arguelles, Andrix +6 more
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Pyrroloquinoline quinone (PQQ) is the organic cofactor in soybean lipoxygenase‐1 [PDF]
FEBS Letters, 1988 Treatment of soybean lipoxygenase‐1 (SLO) with phenylhydrazine (PH) induced inactivation and a maximum (350 nm) in the absorption spectrum of the enzyme. To detach the product having this absorption maximum, proteolysis was required. The product appeared to be the C(5) phenylhydrazone of pyrroloquinoline quinone (PQQ).
van der Meer, Robert A. +1 more
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Transcriptional analysis of pqqD and study of the regulation of pyrroloquinoline quinone biosynthesis in Methylobacterium extorquens AM1 [PDF]
, 1995 Methanol dehydrogenase, the enzyme that oxidizes methanol to formaldehyde in gram-negative methylotrophs, contains the prosthetic group pyrroloquinoline quinone (PQQ).
Lidstrom, Mary E., Ramamoorthi, Roopa
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Methylobacterium sp. 2A is a plant growth-promoting rhizobacteria that has the potential to improve potato crop yield under adverse conditions [PDF]
, 2020 A Gram-negative pink-pigmented bacillus (named 2A) was isolated from Solanum tuberosum L. cv. Desirée plants that were strikingly more developed, presented increased root hair density, and higher biomass than other potato lines of the same age.
Fantino, Elisa Inés +5 more
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Journal of Animal Science and Biotechnology, 2019 Background Pyrroloquinoline quinone (PQQ), which is a water soluble, thermo-stable triglyceride-quinone, is widely distributed in nature and characterized as a mammalian vitamin-like redox cofactor.
Boru Zhang +6 more
doaj +1 more source
SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes [PDF]
, 2014 S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate isomerase (TIM) barrel fold with N- and C-terminal extensions that tailor the ...
Drennan, Catherine L. +2 more
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Bioelectrocatalytic activity of reconstituted peroxidase on hemin-terminated PQQ-modified electrodes
Sensors and Actuators Reports, 2022 Efficient direct electrical communication between an enzyme redox center and an electrode is of great interest from the viewpoints of application to reagentless biosensors and biofuel cells.
Kikuo Komori, Tomoki Aikawa
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Whole-genome sequence analysis of Bombella intestini LMG 28161T, a novel acetic acid bacterium isolated from the crop of a red-tailed bumble bee, Bombus lapidarius [PDF]
, 2016 The whole-genome sequence of Bombella intestini LMG 28161(T), an endosymbiotic acetic acid bacterium (AAB) occurring in bumble bees, was determined to investigate the molecular mechanisms underlying its metabolic capabilities.
Borremans, Wim +7 more
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Pyrroloquinoline Quinone Reprograms the Single-Cell Landscape of Immune Aging in Hematopoietic Immune System. [PDF]
Aging CellThis study demonstrates that aging induces oxidative stress and inflammation in the hematopoietic immune system, resulting in immune homeostasis dysfunction, including alterations in B cells and hematopoietic stem cells, senescent cells (SnCs) accumulation, and senescence‐associated secretory phenotypes (SASPs) production. Notably, the study highlights
Liu X +11 more
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Engineering thermal stability and solvent tolerance of the soluble quinoprotein PedE from Pseudomonas putida KT2440 with a heterologous whole-cell screening approach [PDF]
, 2018 Due to their ability for direct electron transfer to electrodes, the utilization of rare earth metals as cofactor, and their periplasmic localization, pyrroloquinoline quinone‐dependent alcohol dehydrogenases (PQQ‐ADHs) represent an interesting class of ...
Klebensberger, Janosch +1 more
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