Reciprocal diurnal changes of phosphoenolpyruvate carboxylase expression and cytosolic pyruvate kinase, citrate synthase and NADP‐isocitrate dehydrogenase expression regulate organic acid metabolism during nitrate assimilation in tobacco leaves [PDF]
Wolf‐Rüdiger Scheible+2 more
openalex +1 more source
PGC‐1α Activation by Polyphenols: A Pathway to Thermogenesis
Polyphenols, derived from dietary sources such as berries, undergo digestion and interact with gut microbiota, leading to their metabolization in the liver. This process influences bile acid composition, which in turn activates PGC1α, a key regulator of mitochondrial biogenesis and thermogenesis.
Nicholas Vannuchi, Luciana Pisani
wiley +1 more source
Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer. [PDF]
Woolbright BL+7 more
europepmc +1 more source
Red cell glucose‐6‐phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population [PDF]
Jürgen May+8 more
openalex +1 more source
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo+2 more
wiley +1 more source
Pyruvate dehydrogenase kinase from Arabidopsis thaliana: a protein histidine kinase that phosphorylates serine residues [PDF]
Jay J. Thelen+2 more
openalex +1 more source
ABSTRACT Metaproteomics is a valuable approach to characterize the biological functions involved in the gut microbiota (GM) response to dietary interventions. Ketogenic diets (KDs) are very effective in controlling seizure severity and frequency in drug‐resistant epilepsy (DRE) and in the weight loss management in obese/overweight individuals.
Alessandro Tanca+3 more
wiley +1 more source
Selective Modification of Pyruvate Dehydrogenase Kinase Isoform Expression in Rat Pancreatic Islets Elicited by Starvation and Activation of Peroxisome Proliferator–Activated Receptor-α [PDF]
Mary C. Sugden+3 more
openalex +1 more source
Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre+3 more
wiley +1 more source
Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle
Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production. In many types of cancers this leads, even in the presence of oxygen, to the secretion of carbon equivalents ...
Capuani, Fabrizio+3 more
core +1 more source