Results 221 to 230 of about 181,145 (327)

Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants. [PDF]

Mol Cells, 2022
Lee Y, Kim J, Kim H, Han JE, Kim S, Kang KH, Kim D, Kim JM, Koh H.   +8 more
europepmc   +1 more source

Discrete and cell‐specific hypoxic responses in Arabidopsis roots resolved by single‐nuclei transcriptomics

New Phytologist, EarlyView.
Summary With the intensification of unpredictable flooding events because of global warming, there is a need to understand how root cells perceive and respond to oxygen deprivation. The use of high‐throughput single‐nuclei RNA‐sequencing (snRNA‐Seq) allows the examination of gene expression profiles in discrete cell types.
Robert D. Hill, Sean M. Robertson, Abir U. Igamberdiev, Mohammed M. Mira, Olivia Wilkins, Claudio Stasolla   +5 more
wiley   +1 more source

Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure. [PDF]

J Am Heart Assoc
Hua X, Sun Z, Wang C, Cui H, Shan D, Tao M, Cui Z, Chang Y, Bao M, Mo H, Chen X, Song J.   +11 more
europepmc   +1 more source

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity. [PDF]

Anim Nutr, 2022
Luo Y, Zhou W, Li R, Limbu SM, Qiao F, Chen L, Zhang M, Du ZY.   +7 more
europepmc   +1 more source

Optimization of carbon and nitrogen utilization for enhanced photosynthesis, biomass and yield by coexpression of phosphoenolpyruvate carboxylase, aspartate aminotransferase and glutamine synthetase in Brassica juncea

Plant Biotechnology Journal, EarlyView.
Summary Coexpression of genes involved in carbon (C) and nitrogen (N) metabolism offers a promising avenue for improving crop yield. This study investigated the impact of coexpressing phosphoenolpyruvate carboxylase [ZmPEPC (P)], aspartate aminotransferase [GmAspAT (A)] and glutamine synthetase [NtGS (G)] in Brassica juncea to enhance plant yield ...
Mamta, Shiv Shanker Pandey, Anish Kaachra, Sachin Vashisath, Dinesh Kumar, Sanjay Kumar   +5 more
wiley   +1 more source

Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4. [PDF]

BMC Nephrol
Areloegbe SE, Atuma CL, Aturamu A, Ajadi IO, Adelekan OE, Ajadi MB, Akintayo CO, Omoruyi GO, Onyekweli SO, Anifowose OF, Amusa OA, Ajayi K, Oyewole PA, Adegoke TE, Olaniyi KS.   +14 more
europepmc   +1 more source

Corrigendum to "Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis" [Liver Res. 2 (2018) 100-107]. [PDF]

Liver Res, 2023
Choiniere J, Lin MJ, Wang L, Wu J.
europepmc   +1 more source

Engineering Cyanobacteria for High‐Yield Photosynthetic Isoprene Production With Long‐Term Phenotypic Stability

Plant Biotechnology Journal, EarlyView.
Center: Cyanobacterial isoprene production from CO2 and sunlight. Top: CRISPR‐editing for generation of markerless production strains. Top right: Long‐term production assay for strain stability assessment. Bottom right: Engineering of MEP pathway and surrounding metabolism for bottleneck idenfication. Bottom left: Relief of bottleneck by overproduction
Kim N. Janssen, Paul Bolay, Adrian Tüllinghoff, Jörg Toepel, Daniel Spindler, Bruno Bühler, Pia Lindberg   +6 more
wiley   +1 more source

The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice. [PDF]

Hepatol Commun
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE.   +12 more
europepmc   +1 more source

Hsa_circ_0000418 promotes the progression of glioma by regulating microRNA-409-3p / pyruvate dehydrogenase kinase 1 axis. [PDF]

Bioengineered, 2022
Ma Z, Chen Z, Zhou Y, Li Y, Li S, Wang H, Feng J.   +6 more
europepmc   +1 more source