Results 241 to 250 of about 168,834 (385)

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

Biological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison, Josiane Hérault, Justine Marchand, Lionel Ulmann   +3 more
wiley   +1 more source

Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4. [PDF]

BMC Nephrol
Areloegbe SE, Atuma CL, Aturamu A, Ajadi IO, Adelekan OE, Ajadi MB, Akintayo CO, Omoruyi GO, Onyekweli SO, Anifowose OF, Amusa OA, Ajayi K, Oyewole PA, Adegoke TE, Olaniyi KS.   +14 more
europepmc   +1 more source

Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants. [PDF]

Mol Cells, 2022
Lee Y, Kim J, Kim H, Han JE, Kim S, Kang KH, Kim D, Kim JM, Koh H.   +8 more
europepmc   +1 more source

Exploring Long Noncoding RNAs as Regulators of Tumor Ferroptosis: Advances and Challenges

Cancer Science, EarlyView.
Long noncoding RNAs (lncRNAs) play pivotal roles in regulating gene expression and are closely associated with cancer progression, prognosis, and therapeutic resistance. This review highlights recent advancements in understanding how lncRNAs modulate ferroptosis, a regulated form of cell death characterized by iron‐dependent lipid peroxidation ...
Gang Li, Bing Wang, Lisha Ye, Guohua Wang   +3 more
wiley   +1 more source

Increased oxidative phosphorylation through pyruvate dehydrogenase kinase 2 deficiency ameliorates cartilage degradation in mice with surgically induced osteoarthritis. [PDF]

Exp Mol Med
Han J, Kim YH, Han S.
europepmc   +1 more source

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity. [PDF]

Anim Nutr, 2022
Luo Y, Zhou W, Li R, Limbu SM, Qiao F, Chen L, Zhang M, Du ZY.   +7 more
europepmc   +1 more source

Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin [PDF]

, 2009
Sara Connaughton, Farhana Chowdhury, Ramy R. Attia, Shulan Song, Yi Zhang, Marshall B. Elam, George A. Cook, Edwards A. Park   +7 more
openalex   +1 more source

Testis‐Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis

Cell Proliferation, EarlyView.
PDHA2, a testis‐specific subunit of pyruvate dehydrogenase, is required for the conversion of pyruvate to acetyl‐CoA. Its absence results in decreased acetyl‐CoA and precursors for metabolites and energy during spermatogenesis. This results in decreased histone acetylation, defective chromosome structure and moderately reduced crossovers, ultimately ...
Guoqiang Wang, Kailun Fang, Yongliang Shang, Xu Zhou, Qiqi Shao, Si Li, Ping Wang, Charlie Degui Chen, Liangran Zhang, Shunxin Wang   +9 more
wiley   +1 more source

The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice. [PDF]

Hepatol Commun
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE.   +12 more
europepmc   +1 more source

Hsa_circ_0000418 promotes the progression of glioma by regulating microRNA-409-3p / pyruvate dehydrogenase kinase 1 axis. [PDF]

Bioengineered, 2022
Ma Z, Chen Z, Zhou Y, Li Y, Li S, Wang H, Feng J.   +6 more
europepmc   +1 more source