Results 191 to 200 of about 237,828 (335)

Studies on the dietary regulation of jejunal pyruvate kinase and sucrase activities [PDF]

, 1971
Reuben S. Dubois, Ronald W. Gotlin, Denis O. Rodgerson, Donough OʼBrien   +3 more
openalex   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Potent Fluorescent Probe for Target-Engagement Studies of Allosteric Pyruvate Kinase Modulators. [PDF]

Angew Chem Int Ed Engl
Nilsson O, Valaka AP, Håversen L, Bogucka A, Köteles I, Brear P, Rutberg M, Gunnarsson A, Hyvönen M, Grøtli M.   +9 more
europepmc   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Immunoassay for pyruvate kinase M1/2 as an Alzheimer's biomarker in CSF. [PDF]

Open Life Sci
de Geus MB, Kivisäkk P, Trombetta BA, Tijms BM, Visser PJ, Arnold SE, Carlyle BC.   +6 more
europepmc   +1 more source

Pyruvate Kinase [PDF]

, 2020
openaire   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Mitapivat therapy in a patient with nonsense homozygous mutation of the Pyruvate Kinase L/R gene: a case report. [PDF]

Blood Transfus
Ceglie S, Valentini CG, Pellegrino C, Massini G, Teofili L.   +4 more
europepmc   +1 more source

Phosphoenolpyruvate carboxylase kinase involved in C₄ photosynthesis in Flaveria trinervia: cDNA cloning and characterization¹ [PDF]

, 2001
Yuhei Tsuchida, Tsuyoshi Furumoto, Atsushi Izumida, Shingo Hata, Katsura Izui   +4 more
openalex   +1 more source