Results 211 to 220 of about 216,078 (374)
Overall Survival of Patients With Pyruvate Kinase Deficiency in the UK: A Real-World Study. [PDF]
Foy P+11 more
europepmc +1 more source
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard+29 more
wiley +1 more source
Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion. [PDF]
Murao N+8 more
europepmc +1 more source
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley +1 more source
Hexokinase and Pyruvate Kinase Activities in Human and Rat Uterus
Yoshihiro Takahashi+3 more
openalex +2 more sources
Pyruvate Kinase, a Possible Regulatory Enzyme in Higher Plants [PDF]
Ronald G. Duggleby, David T. Dennis
openalex +1 more source
In this study, A04, a compound targeting the degradation of metabolic enzyme PDK1, was developed by PROTAC technology, which significantly inhibited tumor proliferation by disrupting the Warburg effect in cancer cells. In the mouse model, A04 could prolong postoperative survival, and also remodel the immunosuppressive microenvironment, which could ...
Aohua Deng+9 more
wiley +1 more source
High-Resolution Molecular-Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2). [PDF]
Delobelle Q+6 more
europepmc +1 more source
Comparison of the properties of two forms of pyruvate kinase in rat liver and determination of their separate activities during development [PDF]
Marshall C. Middleton, Deryck G. Walker
openalex +1 more source