Results 231 to 240 of about 128,438 (311)

Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2. [PDF]

Nat Commun
Wang RH, Chen PR, Chen YT, Chen YC, Chu YH, Chien CC, Chien PC, Lo SY, Wang ZL, Tsou MC, Chen SY, Chiu GS, Chen WL, Wu YH, Wang LH, Wang WC, Lin SY, Kung HJ, Wang LH, Cheng HC, Lin KT.   +20 more
europepmc   +1 more source

An ecological framework for microbial metabolites in the ocean ecosystem

Limnology and Oceanography Letters, EarlyView.
Abstract The ocean microbe‐metabolite network involves thousands of individual metabolites that encompass a breadth of chemical diversity and biological functions. These microbial metabolites mediate biogeochemical cycles, facilitate ecological relationships, and impact ecosystem health. While analytical advancements have begun to illuminate such roles,
Bryndan P. Durham, Winifred M. Johnson, Catherine C. Bannon, Erin M. Bertrand, Anitra E. Ingalls, Bethanie R. Edwards, Amy Apprill, Angela K. Boysen, Randelle M. Bundy, Huan Chen, Frank X. Ferrer‐González, Cara Fiore, Katherine R. Heal, Constanze Kuhlisch, Shuting Liu, Kaijun Lu, Laurel E. Meke, Sammy Pontrelli, Prabavathy Vaiyapuri Ramalingam, Alicia M. Reigel, Joshua S. Sacks, Jeremy E. Schreier, Jegan Sekar, Mario Uchimiya, Elizabeth B. Kujawinski   +24 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova, Jaroslava Bezdekova, Marketa Vaculovicova   +2 more
wiley   +1 more source

Evaluation of Glucose 6-Phosphate Dehydrogenase, Pyruvate Kinase, and New Generation Inflammation Biomarkers in Prolonged Neonatal Jaundice. [PDF]

Medicina (Kaunas)
Okuyan O, Dumur S, Elgormus N, Uzun H.
europepmc   +1 more source

Effects of Quercetin Metabolites on Glucose‐Dependent Lipid Accumulation in 3T3‐L1 Adipocytes

Molecular Nutrition &Food Research, EarlyView.
Quercetin metabolites (QMs), found in foods like fruits and vegetables, can influence how fat cells process fats and sugars. This study shows that QMs help reduce fat storage and sugar uptake in fat cells when sugar levels are high. Under conditions mimicking caloric restriction, they boost sugar use for energy.
Marco Rendine, Samuele Venturi, Mirko Marino, Claudio Gardana, Peter Møller, Daniela Martini, Patrizia Riso, Cristian Del Bo   +7 more
wiley   +1 more source

Unveiling the anticancer potential of plumbagin: targeting pyruvate kinase M2 to induce oxidative stress and apoptosis in hepatoma cells. [PDF]

RSC Med Chem
Wu J, Ding Z, Tu J, Osama A, Nie Q, Cai W, Zhang B.   +6 more
europepmc   +1 more source

Overexpression of m7G writers METTL1 and BUD23 confers oncogenicity in kidney renal clear cell carcinoma

The Journal of Pathology, EarlyView.
Abstract Emerging evidence shows that N7‐methylguanosine (m7G) modification and its writers contribute to the development of diverse cancers. However, the role of m7G writers in kidney renal clear cell carcinoma (KIRC) remains unclear. In this study we show that the catalytic components of m7G writers, METTL1 and BUD23, are overexpressed in advanced ...
Anni Su, Jessica Tieng, Xueying S Xu, Richard P Tan, Yuchen Feng, Justin J‐L Wong   +5 more
wiley   +1 more source

Defining the Molecular Impacts of Humalite Application on Field‐Grown Wheat (Triticum aestivum L.) Using Quantitative Proteomics

PROTEOMICS, Volume 25, Issue 14, July 2025.
ABSTRACT Increasing global food production demands have resulted in increased fertilizer usage, causing detrimental environmental impacts. Biostimulants, such as humic substances, are currently being applied as a strategy to increase plant nutrient‐use efficiency and minimize environmental impacts within cropping systems.
Lauren E. Grubb, Mohana Talasila, Linda Y. Gorim, Richard Glen Uhrig   +3 more
wiley   +1 more source

Pyruvate Kinase M2: A Potential Regulator of Cardiac Injury Through Glycolytic and Non-glycolytic Pathways. [PDF]

J Cardiovasc Pharmacol
Zeng C, Wu J, Li J.
europepmc   +1 more source