Results 241 to 250 of about 237,828 (335)

Pyruvate kinase splice variants in fibroblasts influence cardiac remodeling after myocardial infarction in male mice. [PDF]

J Mol Cell Cardiol
Wells CK, Nguyen DC, Brainard RE, McNally LA, De Silva M, Brittian KR, Garrett L, Taylor MS, Martinez-Ondaro Y, Howard C, Suluru S, Dassanayaka S, Mohamed TMA, Singhal R, Gibb AA, Lorkiewicz PK, Moore JB, Jones SP, Hill BG.   +18 more
europepmc   +1 more source

Determining the Age-Related Levels of Fecal M2-Pyruvate Kinase in Children with Cystic Fibrosis During the First Decade of Life

, 2017
Millie Garg, Steven T. Leach, Bronwen Needham, Michael J. Coffey, Tamarah Katz, Roxanne Strachan, John Widger, Penelope Field, Yvonne Belessis, Sandra Chuang, Andrew S. Day, Adam Jaffé, Chee Y. Ooi   +12 more
openalex   +2 more sources

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Translational Aspects of DNA Damage Repair in Optimizing Cancer Chemotherapy

Advanced Genetics, EarlyView.
This review systematically delineates the fundamental role and recent advancements in DNA damage response (DDR) within the context of cancer chemotherapy. Particular emphasis is directed toward exploring the interplay between DDR status and chemosensitivity.
Anqi Lin, Jinyue He, Aimin Jiang, Jian Zhang, Quan Cheng, Hengguo Zhang, Wenjun Mao, Peng Luo   +7 more
wiley   +1 more source

Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion. [PDF]

FASEB J
Murao N, Morikawa R, Seino Y, Shimomura K, Maejima Y, Ohno T, Yokoi N, Yamada Y, Suzuki A.   +8 more
europepmc   +1 more source

Ubiquitin-specific protease 7 regulates macrophage polarization via pyruvate kinase M2-mediated metabolic reprogramming in severe acute pancreatitis. [PDF]

Cell Death Dis
Wu Y, Yao X, Yu Q, Yan Q, Huang X, Ke H, Peng C, Xia L.   +7 more
europepmc   +1 more source

Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator

, 2017
Yumi Matsui, Isao Yasumatsu, Takashi Asahi, Takahiro Kitamura, Kazuo Kanai, Osamu Ubukata, Hitoshi Hayasaka, Sachiko Takaishi, Hiroyuki Hanzawa, SHINICHI KATAKURA   +9 more
openalex   +1 more source

High-Resolution Molecular-Dynamics Simulations of the Pyruvate Kinase Muscle Isoform 1 and 2 (PKM1/2). [PDF]

Chemistry
Delobelle Q, Inizan TJ, Adjoua O, Lagardère L, Célerse F, Maréchal V, Piquemal JP.   +6 more
europepmc   +1 more source

Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons

, 2011
Zhenxun Wang, Deblina Chatterjee, Hyun Yong Jeon, Martin Akerman, Matthew G. Vander Heiden, Lewis C. Cantley, Adrian R. Krainer   +6 more
openalex   +2 more sources

The novelty of profilin 2 in regulating pyruvate kinase M2 nuclear translocation and promoting tumor angiogenesis in lung adenocarcinoma. [PDF]

Respir Res
Du X, Ma C, Wang Y, Xu M, Kuang Y, Li M, Wen S, He P, Zhao H, Wang Q.   +9 more
europepmc   +1 more source