Results 241 to 250 of about 216,078 (374)

Pyruvate kinase M2 modulates mitochondrial dynamics and EMT in alveolar epithelial cells during sepsis-associated pulmonary fibrosis. [PDF]

J Transl Med
Feng J, Huang X, Peng Y, Yang W, Yang X, Tang R, Xu Q, Gao Y, He Z, Xing S, Mei S.   +10 more
europepmc   +1 more source

Isolation and characterization of a Saccharomyces cerevisiae mutant deficient in pyruvate kinase activity [PDF]

, 1977
G. F. Sprague
openalex   +1 more source

Functional and evolutionary characterization of potential auxiliary metabolic genes of the global RNA virome

iMetaOmics, EarlyView.
We generated the first comprehensive view of RNA viral auxiliary metabolic genes (AMGs), expanding the known functional type of AMGs by 75%. RNA viruses encode a remarkably high diversity of AMGs, spanning 25 distinct functional categories. Most of these genes are linked to environmental regulation and genetic information processing, with fewer ...
Yang Zhao, Zhihao Zhang, Meiling Feng, Rong Wen, Pengfei Liu   +4 more
wiley   +1 more source

Red Cell Pyruvate Kinase Deficiency With Hypertriglyceridemia: A Case Report. [PDF]

Cureus
Hinge DV, Muranjan M, Taksande A, Hampe P.   +3 more
europepmc   +1 more source

Modulation of the phosphorylation state of rat liver pyruvate kinase by allosteric effectors and insulin.

, 1979
T.H. Claus, M. Raafat El‐Maghrabi, S.J. Pilkis   +2 more
openalex   +1 more source

Leveraging core enzyme structures for microbiota targeted functional regulation: Urease as an example

iMeta, EarlyView.
We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao, Huiyue Zhong, Yue He, Xiaojiao Li, Li Zhu, Zhanbo Xiong, Xiaoyin Zhang, Nan Zheng, Diego P. Morgavi, Jiaqi Wang   +9 more
wiley   +1 more source

How We Treat Hemolytic Anemia Due to Pyruvate Kinase Deficiency. [PDF]

Hematol Rep
Tama-Shekan S, Moreno V, Saba L, Chaulagain CP.   +3 more
europepmc   +1 more source

Interactions of fluorescent analogs of adenine nucleotides with pyruvate kinase [PDF]

, 1973
Jorge R. Barrio, John A. Secrist, Yueh‐hsiu Chien, Peggy Jo Taylor, James L. Robinson, Nelson J. Leonard   +5 more
openalex   +1 more source

Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut

iMeta, EarlyView.
The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen, Wenxin Qu, Mengdi Song, Tianyu Zhang, Chang Liu, Xiaofeng Shi, Xinxin Xu, Jingjing Jiang, Liguo Ding, Fangyu Mo, Zheying Mao, Mingzhu Huang, Ziye Xu, Jiaye Chen, Enhui Shen, Jian Ruan, Jiong Liu, Michael P. Timko, Yu Chen, Longjiang Fan, Shufa Zheng, Yongcheng Wang   +21 more
wiley   +1 more source

Targeting pyruvate kinase M2 for the treatment of kidney disease. [PDF]

Front Pharmacol
Chen DQ, Han J, Liu H, Feng K, Li P.
europepmc   +1 more source