Results 281 to 290 of about 237,828 (335)

Podocyte SIRPα reduction in diabetic nephropathy aggravates podocyte injury by promoting pyruvate kinase M2 nuclear translocation. [PDF]

Redox Biol
Chen Y, Zhang M, Jia R, Qian B, Jing C, Zeng C, Zhu D, Liu Z, Zen K, Li L.   +9 more
europepmc   +1 more source

[Pyruvate kinase].

Postepy higieny i medycyny doswiadczalnej, 1987
openaire   +1 more source

Mitochondrial Respiratory Supercomplex Assembly Factor COX7RP Contributes to Lifespan Extension in Mice

Aging Cell, EarlyView.
Mitochondrial respiratory supercomplex assembly factor COX7RP improves metabolic homeostasis and contributes to lifespan extension in mice. The overexpression of COX7RP reduces white adipose tissue mass and downregulates senescence‐associated secreted phenotype‐related genes in the tissue, suggesting that COX7RP plays a role in preventing aging through
Kazuhiro Ikeda, Sachiko Shiba, Masataka Yokoyama, Masanori Fujimoto, Kuniko Horie, Tomoaki Tanaka, Satoshi Inoue   +6 more
wiley   +1 more source

Response to Mitapivat: A Quinolone Sulfonamide to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency. [PDF]

Am J Ther
Boscoe A, McCracken R, Marathe P, Osman K.   +3 more
europepmc   +1 more source

Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species‐Specific Allergen in King Crab

Allergy, EarlyView.
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li, Jingyuan Bian, Qing Xiong, Brian Shing‐Hei Wong, Stephen Kwok‐Wing Tsui, Kin‐Ming Kwan, Nicki Yat‐Hin Leung, Ting‐Fan Leung, Patrick S. C. Leung, Ka‐Hou Chu, Xiaojun Xiao, Christine Yee‐Yan Wai   +11 more
wiley   +1 more source

The Efficacy of Mitapivat in Case of Transfusion Dependence Linked to Beta Thalassemia Trait Associated with Pyruvate Kinase Deficiency. [PDF]

J Cell Mol Med
Fatigati C, Costantini S, Spasiano A, Ziello B, Gambale A, Ricchi P.   +5 more
europepmc   +1 more source

The Search for Pyruvate Kinase-R Activators; from a Hts Screening Hit Via an Impurity to the Discovery of a Lead Series

C. Yu, L Setti, Shah Nilar, Zhe Li, Soheila Bahmanjah, Yekaterina Myslovaty, Ming Yu, James Patridge, Rebeca Choy, Vincent Siu, Steven Strutt, Richard Zang, Peter Rademacher, Manuel Zancanella   +13 more
openalex   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Flawed Value Assessment of Mitapivat to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency. [PDF]

Am J Ther
Boscoe A.
europepmc   +1 more source