Results 281 to 290 of about 240,985 (333)
Halicin Reduces the Warburg Effect and Overcomes Drug Resistance by Activating the Pyruvate Kinase M2 Pathway for Triple-Negative Breast Cancer Treatment. [PDF]
Gu H +9 more
europepmc +1 more source
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte +3 more
wiley +1 more source
Red Cell Pyruvate Kinase Deficiency With Hypertriglyceridemia: A Case Report. [PDF]
Hinge DV +3 more
europepmc +1 more source
Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA
Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP‐2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that the viscous properties of the cellular microenvironment play a crucial role in the mechanosensitive regulation of growth factor activity.
Finlay Cunniffe +5 more
wiley +1 more source
How We Treat Hemolytic Anemia Due to Pyruvate Kinase Deficiency. [PDF]
Tama-Shekan S +3 more
europepmc +1 more source
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu +8 more
wiley +1 more source
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Targeting pyruvate kinase M2 for the treatment of kidney disease. [PDF]
Chen DQ, Han J, Liu H, Feng K, Li P.
europepmc +1 more source

