Results 31 to 40 of about 491,749 (238)

Genes for asparagine metabolism in Lotus japonicus : differential expression and interconnection with photorespiration [PDF]

, 2017
Background: Asparagine is a very important nitrogen transport and storage compound in plants due to its high nitrogen/carbon ratio and stability.
Betti, Marco, Credali, Alfredo, García Calderón, Margarita, Márquez Cabeza, Antonio José, Pérez Delgado de Torres, Carmen María, Vega Piqueres, José María   +5 more
core   +1 more source

MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation [PDF]

, 2019
Mesenchymal stromal cells (hMSCs) display a pleiotropic function in bone regeneration. The signaling involved in osteoblast commitment is still not completely understood, and that determines the failure of current therapies being used.
Alessandro, Riccardo, Bellavia, Daniele, Carina, Valeria, Conigliaro, Alice, Costa, Viviana, De Luca, Angela, Fini, Milena, Giavaresi, Gianluca, Raimondi, Lavinia, Salamanna, Francesca   +9 more
core   +1 more source

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]

, 2018
Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Bartolomeo S., Di Benedetto P., Giacomelli R., Guggino G., Liakouli V., Panzera N., Ruscitti P., Triolo G.   +11 more
core   +1 more source

M gene targeted qRT-PCR approach for SARS-CoV-2 virus detection

Scientific Reports, 2023
Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) is the gold standard method for SARS-CoV-2 detection, and several qRT-PCR kits have been established targeting different genes of the virus.
Md. Murshed Hasan Sarkar, Showti Raheel Naser, Sanjana Fatema Chowdhury, Md. Salim Khan, Md. Ahashan Habib, Shahina Akter, Tanjina Akhtar Banu, Barna Goswami, Iffat Jahan, Maksudur Rahman Nayem, Md. Akibul Hassan, Md. Imran Khan, Mohammad Fazle Alam Rabbi, Chowdhury Rafiqul Ahsan, Md. Ibrahim Miah, Afzalun Nessa, S. M. Rashed Ul Islam, Mohammed Atiqur Rahman, Md. Aftab Ali Shaikh, Md. Sharfuddin Ahmed   +19 more
doaj   +1 more source

Development of a qRT - PCR Diagnostic Kit for the Detection of FCoV

Cyprus Journal of Medical Sciences
BACKGROUND/AIMS: In recent years, feline infectious peritonitis (FIP), which led to the death of more than 3,000 cats on the island of Cyprus, has become a significant concern. FIP is a fatal disease in cats caused by feline coronavirus (FCoV).
Gülten Tuncel Dereboylu, Gökçe Akan, Melis Kalaycı, Cenk Serhan Özverel, Tamer Şanlıdağ   +4 more
doaj   +1 more source

Evaluation of the performance of a multiplex reverse transcription polymerase chain reaction kit as a potential diagnostic and surveillance kit for rotavirus in Kenya

Tropical Diseases, Travel Medicine and Vaccines, 2019
Background Diarrhea is a serious concern worldwide, especially in developing countries. Rotavirus is implicated in approximately 400,000 infant deaths annually.
Cliff Odhiambo Philip, Margaret Koech, Nancy Kipkemoi, Ronald Kirera, Janet Ndonye, Abigael Ombogo, Mary Kirui, Erick Kipkirui, Brook Danboise, Christine Hulseberg, Stacey Bateman, Alexander Flynn, Brett Swierczewski, Esther Magiri, Elizabeth Odundo   +14 more
doaj   +1 more source

Analytical comparisons of SARS-COV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets

Emerging Microbes and Infections, 2020
Different primers/probes sets have been developed all over the world for the nucleic acid detection of SARS-CoV-2 by quantitative real time polymerase chain reaction (qRT-PCR) as a standard method.
Xinjin Liu, Jiangpeng Feng, Qiuhan Zhang, Dong Guo, Lu Zhang, Tao Suo, Wenjia Hu, Ming Guo, Xin Wang, Zhixiang Huang, Yong Xiong, Guozhong Chen, Yu Chen, Ke Lan   +13 more
doaj   +1 more source

Experimental assessment of robust reference genes for qRT-PCR in lung cancer studies

Frontiers in Oncology, 2023
Stable internal reference genes are crucial for quantitative real-time PCR (qRT-PCR) analyses in lung cancer studies. Widely used reference genes are mostly chosen by intuition or from pan-cancer transcriptome data and lack experimental validation by qRT-
Wei Gu, Wei Gu, Yubin Wang, Ran Xu, Jiamin Li, Jingjie Jin, Jing Zhao, Yang Chen, Yuanzhi Lu, Gong Zhang   +9 more
doaj   +1 more source

Identification of a Proliferation Gene Cluster Associated with HPV E6/E7 Expression Level and Viral DNA Load in Invasive Cervical Carcinoma

, 2005
Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by disrupting TP53 and RB pathways. To investigate molecular mechanisms involved
Anne de La Rochefordière, Christophe Rosty, Dafna Tsafrir, Eytan Domany, F Ferlay, François Radvanyi, Ilan Tsafrir, Jean Paul Thiery, Jérôme Couturier, Martine Peter, Michal Sheffer, Nicolas Stransky, Patricia de Crémoux, Rémy Salmon, Thierry Dorval, Xavier Sastre-Garau   +15 more
core   +1 more source

Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium [PDF]

, 2011
Background: Stromal signalling increases the lateral cell adhesions of prostate epithelial cells grown in 3D culture. The aim of this study was to use microarray analysis to identify significant epithelial signalling pathways and genes in this process ...
Chambers, Karen F., Pearson, Joanna F., Pellacani, Davide, Aziz, Naveed, Gužvić, Miodrag, Klein, Christoph A., Lang, Shona H.   +6 more
core   +4 more sources