Results 81 to 90 of about 1,108,829 (262)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

qRT-PCR confirmation of snoRNA expression.

, 2016
SNORD46 and SNORD89 were confirmed to be down–regulated in tumor, relative to normal samples using qRT-PCR platform. The Ct values obtained for snoRNAs were normalized to Ct values obtained for RNU6.
Bo Wang (86769), Mieke Heyns (3123006), Sambasivarao Damaraju (102523), Olga Kovalchuk (381590), Preethi Krishnan (1833976), John R. Mackey (102521), Sunita Ghosh (102512), Kathryn Graham (192363)   +7 more
core   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

qRT-PCR, antigen ELISA, and serology results, Lagos, Nigeria.

, 2018
qRT-PCR, antigen ELISA, and serology results, Lagos, Nigeria.
Onikepe Folarin (305194), Bobby Brooke Herrera (814469), Christian T. Happi (305230), Philomena Eromon (5278073), Yichen Lu (111597), Rolake Akinsola (5278064), Donald J. Hamel (5278079), Folasade Ogunsola (269175), Phyllis J. Kanki (459676), Philip Oshun (5278070), Charlotte A. Chang (3232419), Kayode T. Adeyemi (5278076), Alani S. Akanmu (5278067)   +12 more
core   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF & INH Resistance of M. tuberculosis

Frontiers in Microbiology, 2016
Background: Failure to early detect multidrug-resistant tuberculosis (MDR-TB) results in treatment failure and poor clinical outcomes, and highlights the need to rapidly detect resistance to rifampicin (RIF) and isoniazid (INH)Methods: In Multi ...
Jingfu ePeng, Xiaoli eYu, Zhenglin eCui, Wenfei eXue, Ziyi eLuo, Zilu eWen, Minghua eLiu, Danqing eJiang, Heping eZheng, Hai eWu, Shulin eZhang, Yao eLi   +11 more
doaj   +1 more source

qRT-PCR validation of DEGs involved in tryptophan biosynthesis.

, 2019
qRT-PCR validation of DEGs involved in tryptophan biosynthesis.
Shuju Ning (5484932), Xiaogui Gong (6453707), Wei Huang (36889), Daozhi Wei (5484926), Wenjin Lin (5484929), Qi Ye (243032)   +5 more
core   +1 more source

qRT-PCR analysis of AA and LA metabolism-related genes.

, 2023
(A) Among the 15 SNL-dependent up-regulated genes, the expression levels of Cyp2c37, Cyp2c50, Cyp2c54, and Ptgds were analyzed by qRT-PCR. (B) The expression levels of the 5 AA and LA metabolism-related genes were analyzed by qRT-PCR.
Koji Nagao (89791), Sayaka Iizasa (4725381), Keisuke Tsuge (2021161), Teruyoshi Yanagita (89797), Yukio Nagano (284292)   +4 more
core   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida

Journal of Tropical Medicine, 2017
Background. The proper management of patients infected with dengue virus requires early detection. Here, real-time molecular assays have proven useful but have limitations, whereas ELISAs that detect antibodies are still favored but results are obtained ...
Jason H. Ambrose, Shamala Devi Sekaran, Azliyati Azizan   +2 more
doaj   +1 more source