Results 101 to 110 of about 29,743 (315)

Interaction of pyrrolobenzodiazepine (PBD) ligands with parallel intermolecular G-quadruplex complex using spectroscopy and ESI-MS.

PLoS ONE, 2012
Studies on ligand interaction with quadruplex DNA, and their role in stabilizing the complex at concentration prevailing under physiological condition, has attained high interest.
Gajjela Raju, Ragampeta Srinivas, Vangala Santhosh Reddy, Mohammed M Idris, Ahmed Kamal, Narayana Nagesh   +5 more
doaj   +1 more source

Semiconducting Polymers Post‐Functionalized With Ureido‐Pyrimidinone for Robust Stretchable Transistors

Advanced Functional Materials, EarlyView.
The design of intrinsically robust stretchable semiconducting polymers was achieved through OTBS‐mediated post‐functionalization of PDPP2T side chains with UPy units, generating dual hydrogen‐bonding motifs comprising weaker urethane linkages and strong quadruple UPy interactions along the long alkyl side chain, which is crucial for achieving desirable
Dinda Bazliah, Livy Laysandra, Kosuke Terayama, Xingyu Yang, Atsushi Isobe, Tai‐Chin Chiang, Tsuyoshi Michinobu, Yu‐Cheng Chiu   +7 more
wiley   +1 more source

Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes

Journal of Nucleic Acids, 2010
C-myc and Bcl2 are well characterized oncogenes that are capable of forming G-quadruplex structures. Promoter regions of C-myc and Bcl2 forming G-quadruplex structures are chemically synthesized and G-quadruplex structure is formed in presence of 100 mM ...
Narayana Nagesh, Varun K. Sharma, A. Ganesh Kumar, Edwin A. Lewis   +3 more
doaj   +1 more source

Development of Multifunctional Hierarchically Restructured Antibacterial Neural Interfacing Electrodes via Plasma‐Enhanced Atomic Layer Deposition of Zinc Oxide Thin Films

Advanced Functional Materials, EarlyView.
ABSTRACT Next‐generation implantable neural‐interfacing devices are increasingly constrained by the coupled demands of electrode miniaturization, electrochemical performance, and implantation infection risk. Femtosecond laser–based hierarchical surface restructuring (HSR) technology has emerged as a scalable, manufacturing‐compatible platform for ...
Henna Khosla, Wesley Seche, Kriti Panchal, Steven J. May, Ekaterina Pomerantseva, Jacob Elmer, Tyler Cooper, Matthew J. Urban, Hailey Y. Maurer, Gregory A. Caputo, Jeffrey Hettinger, Shahram Amini, Gang Feng   +12 more
wiley   +1 more source

Nanodiamond Sensing in Dynamic Environments With Fast‐Tracking Through Four‐Point Positioning

Advanced Functional Materials, EarlyView.
A four‐point positioning tracking (4PPT) platform enables fast 3D feedback translational tracking of fluorescent nanodiamonds while simultaneously recording ODMR spectra. By integrating real‐time translational tracking with quantum sensing, mobile nanodiamonds are used for in‐situ nanothermometry, nanorheometry, and 6D translation–rotation tracking in ...
Guoli Zhu, Ming‐Zhong Ai, Zhi‐Yu Zhao, Weng‐Hang Leong, Shi‐Ning Chen, Xi Liu, Jing‐Wei Fan, Xi Feng, Ren‐Bao Liu, Yue Cui, Quan Li   +10 more
wiley   +1 more source

Chronic RNA G-quadruplex accumulation in aging and Alzheimer’s disease

eLife
As the world population ages, new molecular targets in aging and Alzheimer’s disease (AD) are needed to combat the expected influx of new AD cases. Until now, the role of RNA structure in aging and neurodegeneration has largely remained unexplored.
Lena Kallweit, Eric Daniel Hamlett, Hannah Saternos, Anah Gilmore, Ann-Charlotte Granholm, Scott Horowitz   +5 more
doaj   +1 more source

Intrinsic Interfacial Energy Alignment Enables ETL‐Free Organic Solar Cells

Advanced Functional Materials, EarlyView.
Molecular orientation of the small‐molecule donor BTR‐Cl induces a vacuum‐level shift that pins the Fermi level at ∼4.4 eV at the active layer/Ag interface, enabling Ohmic contact formation without an electron transport layer. This strategy is extended to ternary PM6:Y6:BTR‐Cl devices, achieving an ETL‐free efficiency of 18.6% with enhanced operational
Heng Liu, Yuang Fu, Cangyu Wang, Luhang Xu, Xian‐Kai Chen, Man Chung Tang, Xinhui Lu   +6 more
wiley   +1 more source

Catalyzing Protein Folding by Chaperones

Biology
Protein folding is a fundamental process essential for cellular growth and health, yet it is also susceptible to errors that can result in misfolding and disease.
Zijue Huang, Scott Horowitz
doaj   +1 more source

Memristive‐Gated RC‐Delay Synaptic Transistors for Time‐Encoded Analog in‐Memory Computing

Advanced Functional Materials, EarlyView.
A Memristive‐Gated Transistor for Time‐Encoded Analog In‐Memory Computing — By exploiting the RC delay of a self‐rectifying interface‐type memristor, nonlinear I–V distortion is structurally bypassed, enabling 3‐bit nonvolatile memory, spike‐timing‐based analog encoding, and hardware‐calibrated reservoir‐computing validation within a unified device ...
Yun‐Seo Shin, Eunjoo Yoo, Ki‐Hoon Son, Hyun‐Sik Kim, Dae‐Hee Han, Jeong Hyeon Son, Seung Hwan Lee, Hong‐Sub Lee   +7 more
wiley   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source