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Luminescent G-quadruplex Probes

Current Pharmaceutical Design, 2012
G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature.
Yang, H   +4 more
openaire   +4 more sources

Research Progress of RNA Quadruplex

Oligonucleotides, 2011
RNA/DNA sequences rich in guanine (G) can form a 4-strand structure, G-quadruplex, which has been extensively researched and observed in mammalian, fungi, and plants, with in vivo existence in eukaryotic cells. Compared with DNA quadruplex, the potential existence of RNA quadruplex appears to
Xiaohui, Ji   +5 more
openaire   +3 more sources

Macrocyclic G-Quadruplex Ligands

Current Medicinal Chemistry, 2010
G-quadruplex stabilizing compounds have recently received increased interest due to their potential application as anticancer therapeutics. A significant number of structurally diverse G-quadruplex ligands have been developed. Some of the most potent and selective ligands currently known are macrocyclic structures which have been modeled after the ...
Nielsen, M C, Ulven, Trond
openaire   +3 more sources

Higher-Order Quadruplex Structures

2012
Structural studies have shown that four G-tracts along a DNA strand are the minimal requirement for intramolecular G-quadruplex formation. Longer DNA sequences containing multiples of four G-tracts could, in principle, form higher-order structures based on multiple G-quadruplex blocks.
openaire   +3 more sources

Recent advances on G-quadruplex for biosensing, bioimaging and cancer therapy

TrAC - Trends in Analytical Chemistry, 2021
Jiaqi Xu, Hailun He, Changbei Ma
exaly  

Selective Interactions of Cationic Porphyrins with G-Quadruplex Structures

Journal of the American Chemical Society, 2001
Haiyong Han   +2 more
exaly  

A Model of Smart G-Quadruplex Ligand

Journal of the American Chemical Society, 2013
Romain Haudecoeur   +2 more
exaly  

Visualizing the quadruplex

Nature Chemistry, 2013
Adam Siddiqui-Jain, Laurence H. Hurley
openaire   +1 more source

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